4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

Product Name: 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
CAS No.: 27568-04-3
Chemical Name: 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
Synonyms: NSC 196905;BUTTPARK 20\09-65;ETHYL 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLATE;ETHYL 4-HYDROXY-8-METHOXY-3-QUINOLINECARBOXYLATE;ethyl 8-methoxy-4-oxo-1H-quinoline-3-carboxylate;2-ethyl-8-methoxy-4-oxo-1H-quinoline-3-carboxylate;Ethyl 8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate;Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate;4-keto-8-methoxy-1H-quinoline-3-carboxylic acid ethyl ester;4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
CBNumber: CB9673423
Molecular Formula: C13H13NO4
Formula Weight: 247.25
MOL File: 27568-04-3.mol

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4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Property

Boiling point:: 373.2±37.0 °C(Predicted)
Density: 1.277
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 2.72±0.50(Predicted)
Appearance: Light yellow to brown Solid

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26-24/25
WGK Germany: 3
HS Code: 29334900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BBO000182
Product name: 4-Hydroxy-8-methoxyquinoline-3-carboxylic acid ethyl ester
Purity: Aldrich
Packaging: 1g
Price: $58.6
Updated: 2025/07/31

TRC

Product number: E945523
Product name: Ethyl4-hydroxy-8-methoxyquinoline-3-carboxylate
Packaging: 500mg
Price: $115
Updated: 2021/12/16

TRC

Product number: E945523
Product name: Ethyl4-hydroxy-8-methoxyquinoline-3-carboxylate
Packaging: 1g
Price: $160
Updated: 2021/12/16

AK Scientific

Product number: V4866
Product name: Ethyl4-hydroxy-8-methoxyquinoline-3-carboxylate
Packaging: 1g
Price: $74
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H29-1-2N
Product name: Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate
Packaging: 1g
Price: $192
Updated: 2021/12/16

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4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Synthesis

104007-09-2

27568-04-3

Step B: Synthesis of ethyl 4-hydroxy-8-methoxyquinoline-3-carboxylate: Diethyl 2-(((2-methoxyphenyl)amino)methylene)malonate (47.6 g, 162 mmol) was suspended in Dowtherm (100 mL) and heated to 250 °C. The reaction mixture was kept in a sand bath overnight, subsequently cooled to room temperature and diluted with pentane (750 mL). The resulting solid product was collected by filtration and washed with hexane to afford the target compound (25.7 g, 64% yield). Mass spectrometry analysis (APCI) showed m/z 248.0 ([M + H]+).

References

[1] Patent: US2007/49603, 2007, A1. Location in patent: Page/Page column 66

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

o-Anisidine Diethyl ethoxymethylenemalonate Diphenyl ether PETROLEUM ETHER

Preparation Products

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4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Suppliers

China 57 Germany 1 India 3 Switzerland 2 United Kingdom 8 United States 12 Global 83

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View Lastest Price from 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co

Product: 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 27568-04-3
Price: US $3.00/KG
Min. Order: 1KG
Purity: 90%-99.9%
Supply Ability: 1000kg
Release date: 2019-07-04

27568-04-3, 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTERRelated Search:

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate 7-BROMO-1-CYCLOPROPYL-8-(DIFLUOROMETHOXY)-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER 4-HYDROXY-6-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester 4-HYDROXY-8-METHOXYQUINOLINE 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLIC ACID 8-METHOXYQUINOLINE 4-HYDROXY-8-METHOXY-QUINOLINE-2-CARBOXYLIC ACID ETHYL ESTER ETHYL 4-HYDROXY-8-(TRIFLUOROMETHOXY)QUINOLINE-3-CARBOXYLATE Moxifloxacin Acyl-b-D-glucuronide 1-CYCLOPROPYL-7-FLUORO-1,4-DIHYDRO-8-METHOXY-4-OXO-3-QUINOLINECARBOXYLIC ACID, ETHYL ESTER ETHYL 8-METHOXY-4-(2-NAPHTHYLOXY)-3-QUINOLINECARBOXYLATE ETHYL 8-METHOXY-4-PHENOXY-3-QUINOLINECARBOXYLATE ETHYL 4-(4-FLUOROPHENOXY)-8-METHOXY-3-QUINOLINECARBOXYLATE BUTTPARK 42\01-38 ETHYL 4-HYDROXY-8-METHOXY-6-NITROQUINOLINE-3-CARBOXYLATE 4-HYDROXY-8-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ETHYL ESTER

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

ETHYL 4-HYDROXY-8-METHOXY-3-QUINOLINECARBOXYLATE

ETHYL 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLATE

BUTTPARK 20\09-65

2-ethyl-8-methoxy-4-oxo-1H-quinoline-3-carboxylate

Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate

Ethyl 8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate

4-keto-8-methoxy-1H-quinoline-3-carboxylic acid ethyl ester

ethyl 8-methoxy-4-oxo-1H-quinoline-3-carboxylate

4-Hydroxy-8-methoxyquinoline-3-carboxylic acid ethyl ester ,95%

NSC 196905

3-Quinolinecarboxylic acid, 4-hydroxy-8-methoxy-, ethyl ester

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH

27568-04-3

blocks

Carboxes

Quinolines

pharmacetical