ChemicalBook > CAS DataBase List > 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

Product Name
4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
CAS No.
27568-04-3
Chemical Name
4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
Synonyms
NSC 196905;BUTTPARK 20\09-65;ETHYL 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLATE;ETHYL 4-HYDROXY-8-METHOXY-3-QUINOLINECARBOXYLATE;ethyl 8-methoxy-4-oxo-1H-quinoline-3-carboxylate;2-ethyl-8-methoxy-4-oxo-1H-quinoline-3-carboxylate;Ethyl 8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate;Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate;4-keto-8-methoxy-1H-quinoline-3-carboxylic acid ethyl ester;4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
CBNumber
CB9673423
Molecular Formula
C13H13NO4
Formula Weight
247.25
MOL File
27568-04-3.mol
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4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Property

Boiling point:
373.2±37.0 °C(Predicted)
Density 
1.277
storage temp. 
Sealed in dry,Room Temperature
form 
solid
pka
2.72±0.50(Predicted)
Appearance
Light yellow to brown Solid
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26-24/25
WGK Germany 
3
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
BBO000182
Product name
4-Hydroxy-8-methoxyquinoline-3-carboxylic acid ethyl ester
Purity
Aldrich
Packaging
1g
Price
$58.6
Updated
2025/07/31
TRC
Product number
E945523
Product name
Ethyl4-hydroxy-8-methoxyquinoline-3-carboxylate
Packaging
500mg
Price
$115
Updated
2021/12/16
TRC
Product number
E945523
Product name
Ethyl4-hydroxy-8-methoxyquinoline-3-carboxylate
Packaging
1g
Price
$160
Updated
2021/12/16
SynQuest Laboratories
Product number
4H29-1-2N
Product name
Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate
Packaging
1g
Price
$192
Updated
2021/12/16
AK Scientific
Product number
V4866
Product name
Ethyl4-hydroxy-8-methoxyquinoline-3-carboxylate
Packaging
1g
Price
$74
Updated
2021/12/16
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4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Synthesis

104007-09-2

27568-04-3

Step B: Synthesis of ethyl 4-hydroxy-8-methoxyquinoline-3-carboxylate: Diethyl 2-(((2-methoxyphenyl)amino)methylene)malonate (47.6 g, 162 mmol) was suspended in Dowtherm (100 mL) and heated to 250 °C. The reaction mixture was kept in a sand bath overnight, subsequently cooled to room temperature and diluted with pentane (750 mL). The resulting solid product was collected by filtration and washed with hexane to afford the target compound (25.7 g, 64% yield). Mass spectrometry analysis (APCI) showed m/z 248.0 ([M + H]+).

References

[1] Patent: US2007/49603, 2007, A1. Location in patent: Page/Page column 66

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

o-Anisidine Diethyl ethoxymethylenemalonate Diphenyl ether PETROLEUM ETHER

Preparation Products

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View Lastest Price from 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co
Product
4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 27568-04-3
Price
US $3.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
1000kg
Release date
2019-07-04

27568-04-3, 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTERRelated Search:

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate 7-BROMO-1-CYCLOPROPYL-8-(DIFLUOROMETHOXY)-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER 4-HYDROXY-6-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester 4-HYDROXY-8-METHOXYQUINOLINE 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLIC ACID 8-METHOXYQUINOLINE 4-HYDROXY-8-METHOXY-QUINOLINE-2-CARBOXYLIC ACID ETHYL ESTER ETHYL 4-HYDROXY-8-(TRIFLUOROMETHOXY)QUINOLINE-3-CARBOXYLATE Moxifloxacin Acyl-b-D-glucuronide 1-CYCLOPROPYL-7-FLUORO-1,4-DIHYDRO-8-METHOXY-4-OXO-3-QUINOLINECARBOXYLIC ACID, ETHYL ESTER ETHYL 8-METHOXY-4-(2-NAPHTHYLOXY)-3-QUINOLINECARBOXYLATE ETHYL 8-METHOXY-4-PHENOXY-3-QUINOLINECARBOXYLATE ETHYL 4-(4-FLUOROPHENOXY)-8-METHOXY-3-QUINOLINECARBOXYLATE BUTTPARK 42\01-38 ETHYL 4-HYDROXY-8-METHOXY-6-NITROQUINOLINE-3-CARBOXYLATE 4-HYDROXY-8-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ETHYL ESTER

  • 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
  • ETHYL 4-HYDROXY-8-METHOXY-3-QUINOLINECARBOXYLATE
  • ETHYL 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLATE
  • BUTTPARK 20\09-65
  • 2-ethyl-8-methoxy-4-oxo-1H-quinoline-3-carboxylate
  • Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate
  • Ethyl 8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate
  • 4-keto-8-methoxy-1H-quinoline-3-carboxylic acid ethyl ester
  • ethyl 8-methoxy-4-oxo-1H-quinoline-3-carboxylate
  • 4-Hydroxy-8-methoxyquinoline-3-carboxylic acid ethyl ester ,95%
  • NSC 196905
  • 3-Quinolinecarboxylic acid, 4-hydroxy-8-methoxy-, ethyl ester
  • 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH
  • 27568-04-3
  • blocks
  • Carboxes
  • Quinolines
  • pharmacetical