GYKI 52466 HYDROCHLORIDE

Product Name: GYKI 52466 HYDROCHLORIDE
CAS No.: 102771-26-6
Chemical Name: GYKI 52466 HYDROCHLORIDE
Synonyms: 466;2466;CS-813;GYKI-5;GYKI52;GYKI 52;Gyki Hcl;gyki52466;GYKI52466HCl;Gyki Hydrochloride
CBNumber: CB9701780
Molecular Formula: C17H16ClN3O2
Formula Weight: 329.78
MOL File: 102771-26-6.mol

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GYKI 52466 HYDROCHLORIDE Property

Boiling point:: 472.8±45.0 °C(Predicted)
Density: 1.39
storage temp.: Desiccate at RT
solubility: DMSO: 0.39 mg/mL
form: solid
pka: 8.14±0.20(Predicted)
color: yellow

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Tocris

Product number: 1454
Product name: GYKI52466dihydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $670
Updated: 2021/12/16

Tocris

Product number: 1454
Product name: GYKI52466dihydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $162
Updated: 2021/12/16

Usbiological

Product number: 255423
Product name: GYKI 52466 dihydrochloride
Packaging: 10mg
Price: $403
Updated: 2021/12/16

TRC

Product number: M303695
Product name: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine
Packaging: 50mg
Price: $545
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 47448
Product name: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine
Packaging: 10mg
Price: $620
Updated: 2021/12/16

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GYKI 52466 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine is a non-competitive AMPA receptor antagonist and was found to have therapeutic potential for cocaine addiction treatment.

Definition

ChEBI: GYKI 52466 is a benzodiazepine.

Biological Activity

Selective non-competitive AMPA receptor antagonist (IC 50 values are 10-20, ~ 450 and >> 50 μ M for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. Has anti-proliferative effects in transformed cells. Also available as part of the AMPA Receptor Tocriset™ . Also available as part of the Kainate Receptor Tocriset™ .

storage

room temperature (desiccate)

GYKI 52466 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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GYKI 52466 HYDROCHLORIDE Suppliers

Canada 1 China 54 Germany 2 India 1 Japan 1 Switzerland 2 United Kingdom 1 United States 13 Global 75

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8014
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

102771-26-6, GYKI 52466 HYDROCHLORIDERelated Search:

Benzophenone hydrazone GYKI 52466 HYDROCHLORIDE ACETONE AZINE

gyki52466

4-(8-METHYL-9H-1,3-DIOXOLO[4,5-H][2,3]BENZODIAZEPIN-5-YL)-BENZENAMINE HYDROCHLORIDE

GYKI 52466 HYDROCHLORIDE

4-(8-Methyl-(9H)-1,3-dioxolo[4.5-h][2.3]benzodiazepine-5-yl)benzenaminehydrochloride

GYKI52466HCl

1-(4-Aminophenyl)-4-methyl-7,8-(methylenedioxy)-5H-2,3-benzodiazepine

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-5-yl)aniline

1-(p-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride

4-(8-Methyl-9H-1,3-dioxolo(4,5-H)(2,3)benzodiazepin-5-yl)benzenamine

Benzenamine, 4-(8-methyl-9H-1,3-dioxolo(4,5-H)(2,3)benzodiazepin-5-yl)-

Gyki Hcl

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenaminedihydrochloride

GYKI 52466 dihydrochloride

Gyki Hydrochloride

4-(8-methyl-8,9-dihydro-7H-[1,3]dioxolo[4,,5,:4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline

GYKI52466;GYKI-52466

CS-813

2466

466

GYKI 52

GYKI-5

GYKI52

102771-26-6

C17H15N3O22HCl

C17H15N3O2HCl

Cell Signaling and Neuroscience

Cell Biology

BioChemical

Ionotropic Glutamate Receptor Modulators

Ion Channels

Ligand-Gated Ion Channels

Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals