GYKI 52466 HYDROCHLORIDE
- Product Name
- GYKI 52466 HYDROCHLORIDE
- CAS No.
- 102771-26-6
- Chemical Name
- GYKI 52466 HYDROCHLORIDE
- Synonyms
- 466;2466;CS-813;GYKI-5;GYKI52;GYKI 52;Gyki Hcl;gyki52466;GYKI52466HCl;Gyki Hydrochloride
- CBNumber
- CB9701780
- Molecular Formula
- C17H16ClN3O2
- Formula Weight
- 329.78
- MOL File
- 102771-26-6.mol
GYKI 52466 HYDROCHLORIDE Property
- Boiling point:
- 472.8±45.0 °C(Predicted)
- Density
- 1.39
- storage temp.
- Desiccate at RT
- solubility
- DMSO: 0.39 mg/mL
- form
- solid
- pka
- 8.14±0.20(Predicted)
- color
- yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 1454
- Product name
- GYKI52466dihydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $670
- Updated
- 2021/12/16
- Product number
- 1454
- Product name
- GYKI52466dihydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $162
- Updated
- 2021/12/16
- Product number
- 255423
- Product name
- GYKI 52466 dihydrochloride
- Packaging
- 10mg
- Price
- $403
- Updated
- 2021/12/16
- Product number
- M303695
- Product name
- 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine
- Packaging
- 50mg
- Price
- $545
- Updated
- 2021/12/16
- Product number
- 47448
- Product name
- 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine
- Packaging
- 10mg
- Price
- $620
- Updated
- 2021/12/16
GYKI 52466 HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine is a non-competitive AMPA receptor antagonist and was found to have therapeutic potential for cocaine addiction treatment.
Definition
ChEBI: GYKI 52466 is a benzodiazepine.
Biological Activity
Selective non-competitive AMPA receptor antagonist (IC 50 values are 10-20, ~ 450 and >> 50 μ M for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. Has anti-proliferative effects in transformed cells. Also available as part of the AMPA Receptor Tocriset™ . Also available as part of the Kainate Receptor Tocriset™ .
storage
room temperature (desiccate)