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NALOXONAZINE DIHYDROCHLORIDE

Product Name
NALOXONAZINE DIHYDROCHLORIDE
CAS No.
82824-01-9
Chemical Name
NALOXONAZINE DIHYDROCHLORIDE
Synonyms
naloxonazine;NALOXONAZINE 2HCL;NALOXONAZINE DIHYDROCHLORIDE;NALOXONAZINE DIHYDROCHLORIDE OPIOID ANTA GONIST;6,6'-Azinobis[4,5α-epoxy-17-(2-propenyl)morphinan-3,14-diol];BIS-[5-ALPHA-4,5-EPOXY-3-14-DIHYDROXY-17-(2-PROPENYL)MORPHAN-6-YLIDENE]HYDRAZINE 2HCL;Bis-[5-α-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)-morphinan-6-ylidene]hydrazinedihydrochloride;bis[(5α)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazone dihydrochloride;BIS(5-ALPHA-4,5-EPOXY-3,14-DIHYDROXY-17-[2-PROPENYL]MORPHINAN-6-YLIDENE)HYDRAZONE DIHYDROCHLORIDE;BIS-[5-ALPHA-4,5-EPOXY-3,14-DIHYDROXY-17-(2-PROPENYL)-MORPHINAN-6-YLIDENE] HYDRAZINE DIHYDROCHLORIDE
CBNumber
CB9708794
Molecular Formula
C38H44Cl2N4O6
Formula Weight
723.69
MOL File
82824-01-9.mol
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NALOXONAZINE DIHYDROCHLORIDE Property

Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: >2 mg/mL
form 
solid
pka
8.92±0.40(Predicted)
color 
off-white to light tan
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
255940
Product name
Naloxonazine dihydrochloride
Packaging
10mg
Price
$353
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007453
Product name
NALOXONAZINE DIHYDROCHLORIDE
Purity
95.00%
Packaging
10MG
Price
$629.42
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007453
Product name
NALOXONAZINE DIHYDROCHLORIDE
Purity
95.00%
Packaging
50MG
Price
$915.63
Updated
2021/12/16
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NALOXONAZINE DIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Naloxonazine Dihydrochloride is a selective μ1 antagonist.

Biological Activity

Potent opioid antagonist, selective for μ 1 receptors.

in vivo

Naloxonazine (0-15 mg/kg, i.p., 20 h) results that (olfactory discriminative stimulus)S+/CS+ correlated responses are significantly reduced by about 55% at a dose of 15 mg/kg, from 14.63 to 6.82. However, greater behavioral inhibition is observed in the (olfactory stimulus)S?/CS? stimulus condition, with a 66% reduction in response rate from 9.00 to 3.00 in male Wistar rats[2].

IC 50

Leishmania

NALOXONAZINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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NALOXONAZINE DIHYDROCHLORIDE Suppliers

China 8 Germany 2 Japan 1 Switzerland 2 United Kingdom 2 United States 4 Global 19
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29496
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
DAYANG CHEM (HANGZHOU) CO.,LTD
Tel
+86-88938639 +86-17705817739
Email
info@dycnchem.com
Country
China
ProdList
53899
Advantage
58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19962
Advantage
58
Guangzhou Weisheng Biotechnology Co., Ltd.
Tel
17765667235
Country
CHINA
ProdList
129
Advantage
58
Guangzhou Junuo Biotechnology Co., Ltd.
Tel
13432975901
Country
CHINA
ProdList
132
Advantage
58

82824-01-9, NALOXONAZINE DIHYDROCHLORIDERelated Search:

2-(1,1-DIMETHYLPROPYL)PHENOL 2-Isopropoxyphenol (R)-(-)-1-Cyclohexylethylamine 4-(2-METHOXYPHENYL)PIPERIDINE 3-tert-Butylphenol 2-Methyl-1-phenyl-2-propanol CYCLOHEXYLPHENYL ETHER 1,2,3,4-TETRAHYDRO-2-NAPHTHYLAMINE 1-Methyl-4-piperidinemethanol 1-PHENYL-3-METHYL-3-PENTANOL 2-BENZYL-2-BUTANOL 1,2,3,4-TETRAHYDRO-2-NAPHTHOL (R)-3-Hydroxypiperidine hydrocloride 2-METHYL-4-PHENYL-2-BUTANOL metazocine 2-sec-Butylphenol Hydrazine dihydrochloride 2-methyl-2-phenylpropane-1,3-diol

  • BIS-[5-ALPHA-4,5-EPOXY-3-14-DIHYDROXY-17-(2-PROPENYL)MORPHAN-6-YLIDENE]HYDRAZINE 2HCL
  • BIS-[5-ALPHA-4,5-EPOXY-3,14-DIHYDROXY-17-(2-PROPENYL)-MORPHINAN-6-YLIDENE] HYDRAZINE DIHYDROCHLORIDE
  • BIS(5-ALPHA-4,5-EPOXY-3,14-DIHYDROXY-17-[2-PROPENYL]MORPHINAN-6-YLIDENE)HYDRAZONE DIHYDROCHLORIDE
  • NALOXONAZINE 2HCL
  • NALOXONAZINE DIHYDROCHLORIDE
  • NALOXONAZINE DIHYDROCHLORIDE OPIOID ANTA GONIST
  • bis[(5α)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazone dihydrochloride
  • naloxonazine
  • 6,6'-Azinobis[4,5α-epoxy-17-(2-propenyl)morphinan-3,14-diol]
  • Bis-[5-α-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)-morphinan-6-ylidene]hydrazinedihydrochloride
  • Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, 2-[(5α)-4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-ylidene]hydrazone
  • 82824-01-9
  • C38H42N4O6
  • Opioid receptor and opioid-like receptor