4-(2-METHOXYPHENYL)PIPERIDINE

Product Name: 4-(2-METHOXYPHENYL)PIPERIDINE
CAS No.: 58333-75-8
Chemical Name: 4-(2-METHOXYPHENYL)PIPERIDINE
Synonyms: 4-(2-Methoxyphenyl);2-(Piperidin-4-yl)anisole;4-(2-METHOXYPHENYL)PIPERIDINE;Piperidine,4-(2-methoxyphenyl)-
CBNumber: CB7669983
Molecular Formula: C12H17NO
Formula Weight: 191.27
MOL File: 58333-75-8.mol

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4-(2-METHOXYPHENYL)PIPERIDINE Property

Melting point:: 54 °C
Boiling point:: 115-118 °C(Press: 1.1 Torr)
Density: 1.003±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 10.22±0.10(Predicted)
Appearance: Off-white to light brown Solid

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-52/53
Safety Statements: 26-36/37/39-61
Hazard Note: Irritant
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: M226553
Product name: 4-(2-Methoxyphenyl)piperidine
Packaging: 500mg
Price: $130
Updated: 2021/12/16

Oakwood

Product number: 033949
Product name: 4-(2-Methoxyphenyl)piperidine
Purity: 97%
Packaging: 250mg
Price: $48
Updated: 2021/12/16

Matrix Scientific

Product number: 113681
Product name: 4-(2-Methoxyphenyl)piperidine
Purity: 97%
Packaging: 1g
Price: $98
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-5N
Product name: 4-(2-Methoxyphenyl)piperidine
Purity: 97%
Packaging: 1g
Price: $116
Updated: 2021/12/16

Matrix Scientific

Product number: 113681
Product name: 4-(2-Methoxyphenyl)piperidine
Purity: 97%
Packaging: 5g
Price: $312
Updated: 2021/12/16

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4-(2-METHOXYPHENYL)PIPERIDINE Chemical Properties,Usage,Production

Synthesis

201609-29-2

58333-75-8

General procedure for the synthesis of 4-(2-methoxyphenyl)piperidine-1-carboxylic acid tert-butyl ester from 4-(2-methoxyphenyl)piperidine-1-carboxylic acid: a solution of 4-(2-methoxyphenyl)piperidine-1-carboxylic acid tert-butyl ester (70 mg, 0.24 mmol) with 10% wet Pd/C (10 mg) in 10 mL of ethyl acetate was purged three times with N2 and then stirred in H2 atmosphere (50 psi) with stirring overnight. After completion of the reaction, the suspension was filtered and the filtrate was evaporated in vacuum to give 4-(2-methoxyphenyl)piperidine (70 mg, yield: 99%) as a colorless oil. 4-(2-methoxyphenyl)piperidine (70 mg, 0.24 mmol) was dissolved in 5 mL HCl/dioxane and stirred overnight at room temperature. After completion of the reaction, the solution was evaporated to dryness in vacuum. The solid was washed with ether to give 4-(2-methoxyphenyl)piperidine hydrochloride (35 mg, yield: 76%) as a white solid.

References

[1] Patent: WO2014/100501, 2014, A1. Location in patent: Paragraph 00407
[2] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 14, p. 1851 - 1856
[3] Journal of Medicinal Chemistry, 2012, vol. 55, # 20, p. 8685 - 8699,15
[4] Journal of Medicinal Chemistry, 2012, vol. 55, # 20, p. 8685 - 8699

4-(2-METHOXYPHENYL)PIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-METHOXYPHENYL)PIPERIDINE Suppliers

Belgium 1 China 59 France 1 Germany 3 India 1 Russia 1 Ukraine 1 United Kingdom 3 United States 10 Global 80

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J & K SCIENTIFIC LTD.

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Syntechem Co.,Ltd

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Chengdu HappySyn Pharmaceutical Technology Co., Ltd.

Tel: 028-85114309 18982182443
Email: yangli@happysyn.com
Country: China
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View Lastest Price from 4-(2-METHOXYPHENYL)PIPERIDINE manufacturers

Career Henan Chemical Co

Product: 4-(2-METHOXYPHENYL)PIPERIDINE 58333-75-8
Price: US $5.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-12

58333-75-8, 4-(2-METHOXYPHENYL)PIPERIDINERelated Search:

Naltrexone hydrochloride MORPHINIUM CHLORIDE HYDROCODONE BITARTRATE NALORPHINE HYDROCHLORIDE THEBAINE 3-METHYLMORPHINE SULFATE SALT NORCODEINE Naloxone hydrochloride NORMORPHINE 4-(3-METHOXYPHENYL) PIPERIDINE HYDROCHLORIDE 4-(4-METHOXY-PHENYL)-PIPERIDINE HYDROCHLORIDE 3-(4-METHOXYPHENYL) PIPERIDINE HYDROCHLORIDE 3-(3-METHOXYPHENYL) PIPERIDINE HYDROCHLORIDE 3-(2-METHOXYPHENYL) PIPERIDINE HYDROCHLORIDE 4-(4-METHOXYPHENYL)PIPERIDINE 4-CYANO-4-(3-METHOXYPHENYL)-1-METHYLPIPERIDINE 1-(4-Methoxyphenyl)piperazine dihydrochloride 4-(2-METHOXYPHENYL) PIPERIDINE HYDROCHLORIDE

4-(2-METHOXYPHENYL)PIPERIDINE

2-(Piperidin-4-yl)anisole

Piperidine,4-(2-methoxyphenyl)-

4-(2-Methoxyphenyl)

58333-75-8

58333-75-9