Boc-Dap-OH

Product Name: Boc-Dap-OH
CAS No.: 73259-81-1
Chemical Name: Boc-Dap-OH
Synonyms: BOC-L-DAP-OH;(S)-3-AMINO-2-(TERT-BUTOXYCARBONYLAMINO)PROPANOIC ACID;BOC-L-DAP;BOC-DPR-OH;BOC-DAP-OH;Boc-Dapa-OH;BOC-L-DAPA-OH;(N-Boc-β-amino)-AL;3-Amino-Boc-L-alanin;Boc-Dap-OH USP/EP/BP
CBNumber: CB9715251
Molecular Formula: C8H16N2O4
Formula Weight: 204.22
MOL File: 73259-81-1.mol

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Boc-Dap-OH Property

Melting point:: 210 °C (dec.)
alpha: -5.5 º (c=1, acetic acid)
Boiling point:: 364.4±37.0 °C(Predicted)
Density: 1.189±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: DMSO (Slightly, Heated, Sonicated), Water (Sparingly, Heated, Sonicated)
form: Solid
pka: 2.88±0.16(Predicted)
color: White to Off-White
optical activity: [α]20/D +5.5±1°, c = 1% in methanol: water (1:1)
BRN: 4182136
InChI: InChI=1S/C8H16N2O4/c1-8(2,3)14-7(13)10-5(4-9)6(11)12/h5H,4,9H2,1-3H3,(H,10,13)(H,11,12)/t5-/m0/s1
InChIKey: KRJLRVZLNABMAT-YFKPBYRVSA-N
SMILES: C(O)(=O)[C@H](CN)NC(OC(C)(C)C)=O
CAS DataBase Reference: 73259-81-1(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
F: 10
HazardClass: IRRITANT
HS Code: 29241990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H260In contact with water releases flammable gases which may ignite spontaneously

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

H336May cause drowsiness or dizziness

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.

P231+P232Handle under inert gas. Protect from moisture.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P308+P313IF exposed or concerned: Get medical advice/attention.

P335+P334Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P402+P404Store in a dry place. Store in a closed container.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 15402
Product name: Boc-Dap-OH
Purity: ≥98.0% (TLC)
Packaging: 1g
Price: $86.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 15402
Product name: Boc-Dap-OH
Purity: ≥98.0% (TLC)
Packaging: 5g
Price: $390
Updated: 2024/03/01

TCI Chemical

Product number: A2470
Product name: (S)-3-Amino-2-(tert-butoxycarbonylamino)propionic Acid
Purity: >95.0%(HPLC)(T)
Packaging: 1g
Price: $25
Updated: 2024/03/01

TCI Chemical

Product number: A2470
Product name: (S)-3-Amino-2-(tert-butoxycarbonylamino)propionic Acid
Purity: >95.0%(HPLC)(T)
Packaging: 5g
Price: $72
Updated: 2024/03/01

Alfa Aesar

Product number: H26919
Product name: N(alpha)-Boc-L-2,3-diaminopropionic acid, 97%
Packaging: 1g
Price: $63.65
Updated: 2024/03/01

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Boc-Dap-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Reactant for:

Protein assembly directed by synthetic molecular recognition motifs
Solid phase synthesis of gramicidin S cyclic analogs with antibiotic and hemolytic activities
Synthesis of HCV protease inhibitor modified analogs
Solid phase synthesis of peptidic V1a receptor agonists
Directed peptide assembly at lipid-water interface

Uses

(S)-3-amino-2-(tert-Butoxycarbonylamino)propionic acid (Boc-Dap-OH) is a derivative of amino acids, mainly used as an intermediate in organic synthesis and pharmaceutical chemistry, and can be used in the synthesis of peptide drug molecules and bioactive molecules.

Preparation

The raw material was dissolved inabsolute ethanol (5 mL), and the reaction flask was immersed in a water bath at 25 C. To the alcoholicsolution, 10% palladium-carbon (22.9 mg) and 1,4-cyclohexadiene (10 equivalents with respect to4; 0.47 mL, 5.0 mmol) were added, and the mixture was allowed to react under magnetic stirringovernight. After filtration over a short pad of Celite 545, the solvent was evaporated under reducedpressure conditions, and the solid residue was partitioned in a 1:1 (v/v) H2O/EtOAc mixture (10 mL).The aqueous phase was separated, back extracted with EtOAc (3 10 mL), concentrated under reducedpressure conditions, and lyophilized.Finally, the target product Boc-Dap-OH is obtained.

Definition

Boc-Dap-OH is an amino acid molecule that is a zwitterion. Therefore, the addition of a base is required to prepare a nucleophilic amino acid. It is commonly acts as a nucleophile to attack the acyl carbon.

Boc-Dap-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-Dap-OH Suppliers

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View Lastest Price from Boc-Dap-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-L-Dap-OH 73259-81-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-09-24

Sichuan Jiaying Lai Technology Co.,LTD

Product: Boc-Dap-OH 73259-81-1
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2019-07-18

Sichuan Jiaying Lai Technology Co.,LTD

Product: Boc-Dap-OH 73259-81-1
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2019-07-18

73259-81-1, Boc-Dap-OHRelated Search:

Cbz-beta-Amino-L-alanine (S)-1-N-BOC-4-N-FMOC-PIPERAZINE-2-CARBOXYLIC ACID (S)-N-1-Boc-N-4-Cbz-2-piperazine carboxylic acid (S)-4-Boc-Piperazine-3-carboxylic acid Boc-Dap-OH (S)-1-N-Boc-piperazine-2-carboxylic acid methyl ester 2,3-Diaminopropionic acid L-2,3-Diaminopropionic acid BOC-DAP(DNP)-OH BOC-L-DPA(BOC)-OH BOC-DAP(FMOC)-OH BOC-AZA-L-LEUCINE BOC-ALBIZZIIN BOC-BETA-N-BENZYLAMINO-L-ALA BOC-DAP(DNP)-OSU BOC-DAP(ALOC)-OH DCHA BOC-DAP(BOC)-OH DCHA BOC-DAP(ALOC)-OH

N-Boc-beta-amino-L-alanine

(2S)-3-amino-2-{[(tert-butoxy)carbonyl]amino}propanoic acid

N-alpha-L-(Butoxycarbonyl)-2,3-diaMinopropionic aci

3-Amino-N-(tert-butoxycarbonyl)-L-alanine 97%

3-Amino-Boc-L-alanin

Boc-Dapa-OH

3-AMINO-(TERT-BUTOXYCARBONYL)-L-ALANINE

Nα-Boc-L-2,3-diaminopropionic acid≥ 98% (HPLC)

L-ALANINE, 3-AMINO-N-[(1,1-DIMETHYLETHOXY)CARBONYL]-

BOC-L-DAP-OH

BOC-L-DAPA-OH

BOC-L-2,3-DIAMINOPROPIONIC ACID

BOC-L-ALPHA,BETA-DIAMINOPROPIONIC ACID

BOC-DPR-OH

BOC-DAP-OH

BOC-ALPHA,BETA-DIAMINOPROPIONIC ACID

(S)-3-AMINO-2-(TERT-BUTOXYCARBONYLAMINO)PROPANOIC ACID

T-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID

N-ALPHA-BOC-(S)-2,3-DIAMINOPROPIONIC ACID

NALPHA-BOC-L-BETA-AMINOALANINE

N-ALPHA-BOC-L-DIAMINOPROPIONIC ACID

N-ALPHA-BOC-L-2,3-DIAMINOPROPIONIC ACID

N-ALPHA-BOC-BETA-AMINO-L-ALANINE

Boc-Dap-OH(Na-Boc-2,3-DiaMinopropionic acid)

3-[(tert-butoxy)(carbaMoyl)aMino]propanoic acid

Nalpha-BOC-beta-AMino-L-alanine, 97% 1GR

Nalpha-Boc-2,3-diaminopropionic Acid 3-Amino-N-(tert-butoxycarbonyl)-L-alanine 3-Amino-N-Boc-L-alanine Boc-Dap-OH Boc-Dpr-OH

(<i>S</i>)-3-AMino-2-Boc-propionic acid

N2-tertbutoxycarbonyl-L-2,3-diaMinopropanoic acid

(S)-3-AMino-2-Boc-propionic acid

3-Amino-N-(tert-butoxycarbonyl)-L-alanine

(S)-2-(AMinoMethyl)-4-(tert-butoxy)-4-oxobutanoic acid

(S)-2-[(tert-Butoxycarbonyl)amino]-3-aminopropionic acid

N2-(tert-Butoxycarbonyl)-(S)-2,3-diaminopropionic acid

N2-tert-Butoxycarbonyl-L-2,3-diaminopropionic acid

Nα-BOC-(S)-β-aminoalanine

Nα-Boc-L-β-aminoalanine

(Tert-Butoxy)Carbonyl Dap-OH

(S)-3-AMino-Boc-Alanine

N-ALPHA-T-BUTOXYCARBONYL-L-ALPHA,BETA-DIAMINOPROPIONIC ACID

N-ALPHA-L-(BUTOXYCARBONYL)2,3-DIAMINOPROPIONIC ACID

N-ALPHA-TERT-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID

(N-BOC-BETA-AMINO)-ALA-OH

N-T-BOC-BETA-AMINO-L-ALANINE

Boc-Dpr-OH, N-Boc-L-2,3-diaminopropanoic acid

Na-Boc-L-2,3-diaminopropionic acid

N-t-BOC-?amino-L-alanine

N-BOC-L-2,3-DIAMINOPROPANOIC ACID

(n-boc-β-amino)-ala-oh

BOC-L-DAP-OH BOC-L-2,3- DIAMINOPROPIONIC ACID

N-ALPHA-T-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID

NALPHA-tert-Butoxycarbonyl-L-2,3-diaminopropionic acid

N-ALPHA-L-(BUTOXYCARBONYL)-2,3-DIAMINOPROPIONIC

N-TERT-BOC-BETA-AMINO-L-ALANINE

3-Amino-Boc-L-alanine

N(ɑ)-Boc-L-2,3-diaminopropionic acid, 97%

3-Amino-(tert-butoxycarbonyl)-L-alanine, Boc-Dap-OH, Boc-Dpr-OH, (S)-3-Amino-2-(tert-butoxycarbonylamino)propanoic acid, Nα-Boc-L-2,3-diaminopropionic acid

3-Amino-(tert-butoxycarbonyl)-L-alanine, Boc-Dpr-OH, (S)-3-Amino-2-(tert-butoxycarbonylamino)propanoic acid, Nα-Boc-L-2,3-diaminopropionic acid