ChemicalBook > CAS DataBase List > D-Glucurone

D-Glucurone

Product Name
D-Glucurone
CAS No.
32449-92-6
Chemical Name
D-Glucurone
Synonyms
GLUCURONOLACTONE;D-GLUCURONOLACTONE;D-GLUCURONO-6,3-LACTONE;glucurolactone;D-GLUCURONO-3,6-LACTONE;glucoxy;glucurone;D-Glucurolactone;D-glucoronolactone;D-Galacturonolactone
CBNumber
CB9718232
Molecular Formula
C6H8O6
Formula Weight
176.12
MOL File
32449-92-6.mol
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D-Glucurone Property

Melting point:
172-175 °C (lit.)
alpha 
19 º (c=10, H2O)
Boiling point:
227.71°C (rough estimate)
Density 
1,76 g/cm3
refractive index 
18.5 ° (C=5, H2O)
storage temp. 
Store below +30°C.
solubility 
water: soluble25mg/mL, clear, colorless
form 
Crystals or Crystalline Powder
pka
11.96±0.60(Predicted)
color 
White
Odor
at 100.00 %. very mild mentholic
Odor Type
mentholic
optical activity
[α]24/D +18.8°, c = 8 in H2O
Water Solubility 
SOLUBLE
Merck 
14,4467
BRN 
83595
InChIKey
OGLCQHRZUSEXNB-IEPORWDDSA-N
LogP
-3.457 (est)
CAS DataBase Reference
32449-92-6(CAS DataBase Reference)
EPA Substance Registry System
D-Glucuronolactone (32449-92-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
2
RTECS 
LZ8930000
TSCA 
Yes
HS Code 
29322980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
851450
Product name
D-(+)-Glucuronic acid γ-lactone
Purity
≥99%
Packaging
100g
Price
$81.6
Updated
2024/03/01
Sigma-Aldrich
Product number
851450
Product name
D-(+)-Glucuronic acid γ-lactone
Purity
≥99%
Packaging
1kg
Price
$686
Updated
2024/03/01
Sigma-Aldrich
Product number
05566
Product name
D-(+)-Glucuronic acid γ-lactone
Purity
analytical standard
Packaging
100mg
Price
$83.6
Updated
2024/03/01
TCI Chemical
Product number
G0055
Product name
D-Glucurono-6,3-lactone
Purity
>99.0%(T)
Packaging
25g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
G0055
Product name
D-Glucurono-6,3-lactone
Purity
>99.0%(T)
Packaging
100g
Price
$87
Updated
2024/03/01
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D-Glucurone Chemical Properties,Usage,Production

Chemical Properties

white crystals or crystalline powder

Uses

D-Glucurono-6,3-lactone is a glucuronic acid derivative studied for its effectiveness against canine hepatitis. It is utilized in the studies such as starting regent in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, required for the preparation of 1-O-acyl glucuronide of the anti-inflammatory drug ML-3000, synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides.

Uses

D-Glucurone is a glucuronic acid derivative. It is used for treating canine hepatitis.

Definition

The γ-lactone of glucuronic acid. Found in plant gums and animal connective tissues.

General Description

D-(+)-Glucuronic acid γ-lactone (Glucourono-γ-lactone, Glucurone or Glycurone) is a carbohydrate derivative. It converted into L-ascorbic acid in animals and human body. Its molecule contains two five-membered rings. Its crystal structure has been studied.

Purification Methods

Dissolve the lactone or mixture of lactone and acid in H2O and concentrate on a steam bath until crystallisation begins. Cool rapidly to room temperature wih stirring. After 2hours the product is filtered off, washed with cold EtOH and dried to m 174-175o and [] D +19.8o (c 5.2, H2O). The amount of free acid can be obtained by titration of an ice-cold aqueous solution with standard alkali. It can be recrystallised from EtOH, EtOH/H2O or MeOH, and the highest recorded m is 180o. [Stacey J Chem Soc 1529 1939, Mehltretter et al. J Am Chem Soc 73 2424 1951, Beilstein 18 III/IV 3055, 18/5 V 33.]

D-Glucurone Preparation Products And Raw materials

Raw materials

DOWEX MAC-3 ION EXCHANGE RESIN D-Glucuronic acid

Preparation Products

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View Lastest Price from D-Glucurone manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
D-Glucurone 32449-92-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-04
Watson Biotechnology Co.,Ltd
Product
D-Glucurone 32449-92-6
Price
US $35.00/kg
Min. Order
25kg
Purity
99%
Supply Ability
20MT
Release date
2024-07-24
Hebei Zhuanglai Chemical Trading Co Ltd
Product
D-Glucurone 32449-92-6
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-26

32449-92-6, D-GlucuroneRelated Search:

Chlorhexidine digluconate SODIUM GLUCOHEPTONATE Corn Peptide Clotrimazole Anise oil D-GLUCURONO-1,4-LACTONE,D-GLUCURONO-6,3-LACTONE,D(+)-GLUCURONO-6,3-LACTONE,GLUCURONO-3,6-LACTONE(-D),D-GLUCURONIC ACID LACTONE 1,2-O-ISOPROPYLIDENE-ALPHA-D-GLUCURONO-6,3-LACTONE,D-GLUCURONO-6,3-LACTONE ACETONIDE,D-Glucurono-6,3-lactone acetonide, 98+% D-Glucuronic acid 4-Iodophenol D-Glucurone Aceglatone (S)-(-)-alpha-Hydroxy-gamma-butyrolactone L-ERYTHRONO-1,4-LACTONE D-LYXONO-1,4-LACTONE Glucososamine sulfate glucurono-1,4-lactone isonicotinoylhydrazone

  • D-Glucurono-6,3-lactone D-Glucuronic Acid Lactone D(+)-Glucurono-3,6-lactone D-(+)-Glucuronic acid γ-lactone Glucuronolactone
  • D-(+)-Glucuronolactone for synthesis
  • b-d-anhydroglucuronate
  • d-glucurono-gamma-lactone
  • D-Glucuronic acid, g-lactone
  • D-Glucorono-6,3-lactone
  • Glucorolactone
  • D(+)-Glucurono-3,6-lactone SynonyM: D-Glucurone
  • D-(+)-Glucuronic acid gaMMa-lactone >=99%
  • D(+)-Glucurono-6,3-lactone >99%, 3-lactone >99%
  • Glcuuronolactone
  • ucurono-6,3-L
  • d-glucuronq-3,6-lactone
  • dicurone
  • gamma-glukurolakton
  • gamma-lactone,d-glucuronicaci
  • glucoxy
  • glucurolactone
  • glucuron
  • glucurone
  • glucuronicacidgamma-lactone
  • glucuronicacidlactone
  • glucurono-6,3-lactone
  • glucuronosan
  • glycurone
  • guronsan
  • reulatts.s.
  • D-GLUCURONOLACTONE AKA D-GLUCURONIC ACID
  • D(+)-Glucurono-6,3-lactone >99%
  • Glucuronic acid lactone (6CI)
  • Glucuronic acid, γ-lactone, D- (8CI)
  • NSC 656
  • GAMMA-GLUCURONOLACTONE
  • D-(+)-Glucurono-6,3-lactone, Glucuronolactone
  • D-(+)-Glucurono-6,3-lactone, D-Glucurone, D-Glucurono-6,3-lactone, Glucuronolactone
  • (2R)-2-[(2S,3S,4S)-3,4-Dihydroxy-5-oxo-oxolan-2-yl]-2-hydroxy-acetaldehyde
  • Glucoxyl
  • GLUCURONOLACTONE(P)
  • D-GLUCURONIC ACID-y-LACTONERESEARCH GRADE
  • D(+)-Glucuronic acid γ-lactone,D-(+)-Glucurono-6,3-lactone, Glucuronolactone
  • D(+)-Glucuronic acid-γ-lactone, synthesis grade
  • D-(+)-Glucuronic acid γ-lactone,D-(+)-Glucurono-6,3-lactone, D-Glucurone, D-Glucurono-6,3-lactone, Glucuronolactone
  • D-Glucuronolactone ,99%
  • 6-lactone
  • D-Glucuro-3
  • D-(+)-Glucuronolacton
  • D(+)-Glucurono-3,6-lactone, 99+% 100GR
  • D(+)-Glucurono-3,6-lactone, 99+% 25GR
  • D-Glucuronic Acid LaCLone
  • GLUCURONOLACTONE(SH)
  • (3aS,6S,6aR)-2,3,6-trihydroxy-3,3a,6,6a-tetrahydro-2H-furo[3,2-b]furan-5-one
  • D-Glucurolactone
  • D-Glucurono-3
  • Glucuronolactone 32449-92-6
  • g-lactone
  • GLUCURONO-3,6-LACTONE(-D)
  • GLUCURONO-GAMMA-LACTONE
  • D-GLUCURONE