ChemicalBook > CAS DataBase List > Aceglatone
Aceglatone
- Product Name
- Aceglatone
- CAS No.
- 642-83-1
- Chemical Name
- Aceglatone
- Synonyms
- Glucaron;Aceglatone;Aceglatone USP/EP/BP;Glucaro-(1→4:6→3)-dilactone diacetate;Furo[3,2-b]furan, D-glucaric acid deriv.;D-Glucaric acid, di-γ-lactone, 2,5-diacetate;2,5-Di-O-acetyl-D-glucaro-(1→4:6→3)-dilactone;O2,O5-diacetylglucaric acid 1,4:6,3-dilactone;Glucaric acid, di-γ-lactone, diacetate, D- (8CI);Glucaric acid, 1,4:6,3-dilactone, diacetate (7CI)
- CBNumber
- CB51177953
- Molecular Formula
- C10H10O8
- Formula Weight
- 258.18
- MOL File
- 642-83-1.mol
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Aceglatone Property
- Melting point:
- 185-186° (Hirasaka)
- Density
- 1.49
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Aceglatone Chemical Properties,Usage,Production
Uses
Aceglatone, an antineoplastic agent, is a β-glucuronidase inhibitor. Aceglatone is a compound that inhibits colon carcinogenesis and prevents the induction of colon cancer by inhibiting the hydrolysis of glucuronides. Aceglatone reduces cell proliferation, induces apoptosis and inhibits DNA synthesis in human colon cancer cells[1].
Definition
ChEBI: Aceglatone is an organic molecular entity.
References
[1] Effects of synthetic and natural in vivo inhibitors of β-glucuronidase on azoxymethane-induced colon carcinogenesis in rats DOI:10.3892/mmr_00000022
Aceglatone Preparation Products And Raw materials
Raw materials
Preparation Products
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