(S)-5-Hydroxymethyldihydrofuran-2-one

Product Name: (S)-5-Hydroxymethyldihydrofuran-2-one
CAS No.: 32780-06-6
Chemical Name: (S)-5-Hydroxymethyldihydrofuran-2-one
Synonyms: 5-(Hydroxymethyl)dihydro-2(3H)-furanone;(S)-(+)-γ-Hydroxymethyl-γ(S)-Gamma-Hydroxymethyl-Gamma;(S)-4-HYDROXYMETHYL BUTYROLACTONE;(5S)-5-(hydroxyMethyl)oxolan-2-one;(s)-γ-hydroxymethyl-γ-butyrolactone;(S)-5-Hydroxymethyldihydrofuran-2-on;(S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE;(S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE
CBNumber: CB6702069
Molecular Formula: C5H8O3
Formula Weight: 116.12
MOL File: 32780-06-6.mol

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(S)-5-Hydroxymethyldihydrofuran-2-one Property

Melting point:: 72-74 °C
alpha: 56 º (c=3 in chloroform)
Boiling point:: 110-115 °C/0.2 mmHg (lit.)
Density: 1.237 g/mL at 25 °C (lit.)
refractive index: n20/D 1.471(lit.)
Flash point:: >230 °F
storage temp.: 2-8°C
pka: 14.12±0.10(Predicted)
form: clear liquid
color: Colorless to Almost colorless
optical activity: [α]20/D +56°, c = 3 in chloroform
BRN: 1680284
CAS DataBase Reference: 32780-06-6(CAS DataBase Reference)
NIST Chemistry Reference: (S)-(+)-2',3'-dideoxyribonolactone(32780-06-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 23-24/25-37/39-26
WGK Germany: 3
HS Code: 29322090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 348902
Product name: (S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone
Purity: 95%
Packaging: 1g
Price: $226
Updated: 2023/06/20

TCI Chemical

Product number: H0958
Product name: (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone
Purity: >94.0%(GC)
Packaging: 1g
Price: $114
Updated: 2024/03/01

TCI Chemical

Product number: H0958
Product name: (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone
Purity: >94.0%(GC)
Packaging: 5g
Price: $504
Updated: 2024/03/01

TRC

Product number: H973063
Product name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one
Packaging: 1g
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 119181
Product name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one
Purity: 95+%
Packaging: 1g
Price: $72
Updated: 2021/12/16

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(S)-5-Hydroxymethyldihydrofuran-2-one Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liqui

Uses

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone can be used as a chiral synthon to synthesize:

Potent nucleoside, acetylcholine, and (+)-muricatacin analogs.
Mevinic acids, which are LDL cholesterol-lowering agents.
Adenine based anti-HIV agent named β-F-ddA.

General Description

Dihydro-5-(hydroxymethyl)-2(3H)-furanone is a chiral building block widely used in the synthesis of many natural products and few biologically significant compounds like anti-HIV dideoxynucleosides. It is also used in the synthesis of optically active ligands.

(S)-5-Hydroxymethyldihydrofuran-2-one Preparation Products And Raw materials

Raw materials

Borane-methyl sulfide complex L-Glutamic acid Sodium nitrite Tetrahydrofuran Benzene Ethyl acetate Hydrochloric acid Methanol PETROLEUM ETHER

Preparation Products

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(S)-5-Hydroxymethyldihydrofuran-2-one Suppliers

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View Lastest Price from (S)-5-Hydroxymethyldihydrofuran-2-one manufacturers

Career Henan Chemical Co

Product: (S)-5-Hydroxymethyldihydrofuran-2-one 32780-06-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

32780-06-6, (S)-5-Hydroxymethyldihydrofuran-2-oneRelated Search:

Tris(hydroxymethyl)nitromethane Tetrahydrofuran (Hydroxymethyl)urea methylol cellulose Tris(hydroxymethyl)aminomethane Furazolidone BETA-BUTYROLACTONE 2,5-Dihydrofuran Methyl 2-hydroxyethyl cellulose Dihydromyrcenol 2,3-Dihydrobenzofuran 2,3-Dihydrofuran 2-Methylfuran 2-Hydroxyethyl methacrylate CARBOXYMETHYLCELLULOSE SODIUM SALT Trimethylolpropane Gamma Butyrolactone (1S)-(-)-Camphanic acid

(S)-(+)-gamma-Hydroxymethyl-gamma-butyrolactone,97%

(S)-Gamma-Hydroxymethyl-Gamma

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone ,97%

(5S)-5-(HYDROXYMETHYL)-3,4,5-TRIHYDROFURAN-2-ONE

(5S)-(+)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one

(S)-(+)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone (S)-(+)-5-Hydroxymethyltetrahydro-2-furanone

5-Oxo-tetrahydro-furan-2-carboxylic acid ethyl ester

(5S)-5-(hydroxyMethyl)oxolan-2-one

2(3H)-Furanone,dihydro-5-(hydroxyMethyl)-, (5S)-

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone 95%

(<i>S</i>)-(+)-&gamma

-Hydroxymethyl-&gamma

5-(Hydroxymethyl)dihydro-2(3H)-furanone

(S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE

(S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)FURANONE

(S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTON

(S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE

(S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE

(S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE

(S)-(+)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE

(S)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE

(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran

DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE (S-)

2(3H)-FURANONE, DIHYDRO-5-(HYDROXYMETHYL)-,(S)

(S)-4-HYDROXYMETHYL BUTYROLACTONE

(S)-5-HYDROXYMETHYL-2-OXOTETRAHYDROFURAN

(S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE

(S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE

(S)-(+)-5-HYDROXYMETHYLTETRAHYDRO-2-FURANONE

(S)-5-Hydroxymethyldihydrofuran-2-on

(S)-γ-Hydroxymethyl-γ-butyrolactone, (S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran

(S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran

(S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)- FURANONE, 95% (98% EE/GLC)

(S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYRO- &

(s)-γ-hydroxymethyl-γ-butyrolactone

(S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE 98%

(S)-(+)-γ-Hydroxymethyl-γ-butyrolactone&gt

(5S)-5-(Hydroxymethyl)dihydro-2(3H)-furanone

32780-06-6

Asymmetric Synthesis

Chiral Building Blocks

Heterocyclic Building Blocks

Furans

chiral

Chiral Reagent