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2-Chlorobenzoyl chloride

Product Name
2-Chlorobenzoyl chloride
CAS No.
609-65-4
Chemical Name
2-Chlorobenzoyl chloride
Synonyms
O-CHLOROBENZOYL CHLORIDE;OCOC;o-ChL;SKL750;orobenzoyL;o-Chlorobenzoylchlor;chlorobenzoylchloride;o-Chlorbenzoylchlorid;o-Chlorobenzoylchlorid;LABOTEST-BB LTBB000568
CBNumber
CB9721544
Molecular Formula
C7H4Cl2O
Formula Weight
175.01
MOL File
609-65-4.mol
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2-Chlorobenzoyl chloride Property

Melting point:
-4--3 °C (lit.)
Boiling point:
238 °C (lit.)
Density 
1.382 g/mL at 25 °C (lit.)
vapor pressure 
0.1 hPa (20 °C)
refractive index 
n20/D 1.572(lit.)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
form 
Liquid
color 
Clear colorless to very slightly yellow
explosive limit
1.5-9.4%(V)
Water Solubility 
Soluble in acetone, ether, and alcohol. Solubility in water it decomposes.
Sensitive 
Moisture Sensitive
BRN 
386435
CAS DataBase Reference
609-65-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzoyl chloride, 2-chloro-(609-65-4)
EPA Substance Registry System
Benzoyl chloride, 2-chloro- (609-65-4)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45-28A
RIDADR 
UN 3265 8/PG 2
WGK Germany 
1
19-21
Autoignition Temperature
600 °C
Hazard Note 
Corrosive/Moisture Sensitive
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29163900
Toxicity
LD50 orally in Rabbit: 3250 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
103918
Product name
2-Chlorobenzoyl chloride
Purity
95%
Packaging
5g
Price
$55.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21989
Product name
2-Chlorobenzoyl chloride
Purity
for synthesis
Packaging
250ML
Price
$51.3
Updated
2024/03/01
Sigma-Aldrich
Product number
103918
Product name
2-Chlorobenzoyl chloride
Purity
95%
Packaging
100g
Price
$107
Updated
2024/03/01
TCI Chemical
Product number
C0140
Product name
2-Chlorobenzoyl Chloride
Purity
>98.0%(GC)(T)
Packaging
25mL
Price
$24
Updated
2024/03/01
TCI Chemical
Product number
C0140
Product name
2-Chlorobenzoyl Chloride
Purity
>98.0%(GC)(T)
Packaging
100mL
Price
$37
Updated
2024/03/01
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2-Chlorobenzoyl chloride Chemical Properties,Usage,Production

Chemical Properties

clear colourless to very slightly yellow liquid

Uses

2-Chlorobenzoyl chloride, is used in organic synthesis. It is used as a pharmaceutical intermediate for eg as an intermediate of clotrimazolc, preparation of p-chlorobenzoic acid and production of trichloro-acaricide.

Definition

ChEBI: An acyl chloride consisting of benzoyl chloride having a chloro substituent in the ortho-position.

General Description

2-Chlorobenzoyl chloride reacts with aromatic amines and ammonium thiocyanate using polyethylene glycol-400 as the catalyst under the condition of solid-liquid phase-transfer catalysis to form N-aryl-N′(2-chlorobenzoyl) thioureas. 2-Chlorobenzoyl chloride causes the acylation of polystyrene during the preparation and regeneration of the polystyrene-based resin.

Synthesis

A process for preparing 2-chlorobenzoyl chloride which comprises reacting 2-chlorobenzaldehyde with chlorine in the presence of phosphorus pentachloride at a temperature of from 50° to 200° C. and wherein the 2-chlorobenzaldehyde: phosphorus pentachloride ratio is from 1:0.05 to 1:0.2. Phosphorus pentachloride (41.5 g, 0.2 mole) was added to 2-chlorobenzaldehyde (289.7 g, 2.0 mole, 97%). After the ensuing exotherm had subsided, the resulting red solution was heated to 160° C. A stream of chlorine was introduced through a sparge tube into the solution for six hours. (Gas chromatography indicated 96.5% conversion.) The solution was then cooled and distilled under reduced pressure, giving 325.4 grams of 2-chlorobenzoyl chloride, which boiled at 135° to 140° C. at 16 millimeters of mercury. The yield of 2-Chlorobenzoyl chloride was 93% (98.5% pure).

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2-Chlorobenzoyl chloride Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from 2-Chlorobenzoyl chloride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2-Chlorobenzoyl chloride 609-65-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-01
Hebei Chuanghai Biotechnology Co,.LTD
Product
Chlorobenzoyl Chlorid Orobenzoyl 609-65-4
Price
US $19.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2024-08-19
Hebei Fengqiang Trading Co., LTD
Product
2-Chlorobenzoyl chloride 609-65-4
Price
US $100.00/drum
Min. Order
1drum
Purity
99
Supply Ability
5000
Release date
2023-09-11

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