ChemicalBook > CAS DataBase List > 8-HYDROXYGUANOSINE

8-HYDROXYGUANOSINE

Product Name: 8-HYDROXYGUANOSINE
CAS No.: 3868-31-3
Chemical Name: 8-HYDROXYGUANOSINE
Synonyms: 8-OHG;8-OXO-G;8-OH-GUO;NSC 90393;RNA adduct;8-Hydroxy-Gr;8-OXOGUANOSINE;8-Oxo-D-guanosine;8-HYDROXYGUANOSINE;7,8-dihydro-8-oxo-guanosin
CBNumber: CB9734795
Molecular Formula: C10H13N5O6
Formula Weight: 299.24
MOL File: 3868-31-3.mol

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8-HYDROXYGUANOSINE Property

Melting point:: 232-235°C
Density: 2.43±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) Water (Slightly, Heated,Sonicated)
form: White to off-white powder.
pka: 7.75±0.20(Predicted)
color: White to Off-White
Stability:: Hygroscopic

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Safety

Toxicity: sce-hmn-lym 100 nmol/L MUREAV 403,223,1998

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TCI Chemical

Product number: O0661
Product name: 8-Hydroxyguanosine
Packaging: 50MG
Price: $450
Updated: 2025/07/31

Cayman Chemical

Product number: 89300
Product name: 8-Hydroxyguanosine
Purity: ≥98%
Packaging: 1mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 89300
Product name: 8-Hydroxyguanosine
Purity: ≥98%
Packaging: 5mg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 89300
Product name: 8-Hydroxyguanosine
Purity: ≥98%
Packaging: 10mg
Price: $223
Updated: 2024/03/01

Cayman Chemical

Product number: 89300
Product name: 8-Hydroxyguanosine
Purity: ≥98%
Packaging: 25mg
Price: $510
Updated: 2024/03/01

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8-HYDROXYGUANOSINE Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro

Uses

It is a representative metabolite derived by the oxidation of Guanosine (G) and is regarded as a marker of oxidative stress in the cells.

Definition

ChEBI: 8-Hydroxyguanosine is a purine nucleoside.

Safety Profile

Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

in vivo

8-Hydroxyguanosine (60 mg/kg, i.p., 4 h before LPS (1 mg/kg) injected) attenuates the LPS-induced increase in serum levels of TNF-α and IL-18 in LPS-treated mice^[4].

Animal Model:	LPS-treated mice^[4]
Dosage:	60 mg/kg
Administration:	i.p., 4 h before LPS (1 mg/kg) injected
Result:	Attenuated the LPS-induced increase in serum levels of TNF-α and IL-18, but was not significant for IL-6 and IL-12p70 in mice.

IC 50

Human Endogenous Metabolite

8-HYDROXYGUANOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 8-HYDROXYGUANOSINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 8-HYDROXYGUANOSINE 3868-31-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-14

3868-31-3, 8-HYDROXYGUANOSINERelated Search:

Phenol Hydroxyapatite FETAL BOVINE SERUM USA ORIGIN CATALASE 2'-Deoxy-8-hydroxyguanosine 1,3-Dihydro-4-methyl-2H-imidazol-2-one 8-Benzyloxyguanosine 1H-IMIDAZOL-2-OL 8-(Allyloxy)guanosine 8-HYDROXYGUANOSINE Tri-O-acetyl-8-(allyloxy)guanosine 8-hydroxyguanosine triphosphate Anti-8-Hydroxyguanosine (Goat) Hydroxyguanosine 8 (8-OHG) ANTI-8-HYDROXYGUANOSINE,ANTI-8-HYDROXYGUANOSINE GOAT PAB 8-Hydroxyguanosine, Goat anti- 7-hydroxyguanosine 5'-monophosphate

8-Oxo-D-guanosine

2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione

2-amino-9-beta-d-ribofuranosylpurine-6,8(1h,9h)-dione

7,8-dihydro-8-oxo-guanosin

9h)-dione,2-amino-9-beta-d-ribofuranosyl-purine-8(1h

8-HYDROXYGUANOSINE

8-OHG

8-OH-GUO

8-OXO-G

8-OXOGUANOSINE

7,8-DIHYDRO-8-OXO-GUANOSINE

2-AMino-9-β-D-ribofuranosyl-purine-6,8(1H,9H)-dione

NSC 90393

8-Hydroxy-Gr

Guanosine, 7,8-dihydro-8-oxo-

8-HYDROXYGUANOSINE USP/EP/BP

8-Hydroxyguanosine, marker of oxidative stress,RNA adduct

2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-hydroxy-1H-purin-6(9H)-one

Endogenous Metabolite,8 Hydroxyguanosine,Inhibitor,8Hydroxyguanosine,8-Hydroxyguanosine,inhibit

marker of oxidative stress

RNA adduct

8-Hydroxyguanosine, biomarker for oxidative damage

8-Hydroxyguanosine, 10 mM in DMSO

3868-31-3

C10H13N5O6

Carbohydrates & Derivatives

Metabolites & Impurities

Nucleotides and Nucleosides

Bases & Related Reagents

Labeling and Diagnostics Reagents

Nucleotides