ChemicalBook > CAS DataBase List > Citraconic anhydride
Citraconic anhydride
- Product Name
- Citraconic anhydride
- CAS No.
- 616-02-4
- Chemical Name
- Citraconic anhydride
- Synonyms
- CTA;2,5-Furandione, 3-Methyl-;3-Methylmaleic anhydride;3-methyl-furan-2,5-dione;alpha-methylmaleicanhydride;CITRACONIC ANHYDRIDE;methyl-maleicanhydrid;3-methyl-5-furandione;Indobufen Impurity 53;METHYLMALEIC ANHYDRIDE
- CBNumber
- CB9761753
- Molecular Formula
- C5H4O3
- Formula Weight
- 112.08
- MOL File
- 616-02-4.mol
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Citraconic anhydride Property
- Melting point:
- 6-10 °C (lit.)
- Boiling point:
- 213-214 °C (lit.)
- Density
- 1.247 g/mL at 25 °C (lit.)
- vapor density
- 4 (vs air)
- vapor pressure
- 1.3 hPa ( 47 °C)
- refractive index
- n20/D 1.471(lit.)
- Flash point:
- 215 °F
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Liquid
- color
- Clear colorless to very slightly yellow
- Water Solubility
- decomposes
- Sensitive
- Moisture Sensitive
- BRN
- 1835
- Dielectric constant
- 40.3（20℃）
- LogP
- -0.232 (est)
- CAS DataBase Reference
- 616-02-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 2,5-Furandione, 3-methyl-(616-02-4)
- EPA Substance Registry System
- 2,5-Furandione, 3-methyl- (616-02-4)
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Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25-36/37/38-42/43-34-24
- Safety Statements
- 26-36/37/39-45-28A-23-36/37
- RIDADR
- UN 2810 6.1/PG 3
- WGK Germany
- 3
- RTECS
- GE6825000
- F
- 10-21
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29171990
- Hazardous Substances Data
- 616-02-4(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 125318
- Product name
- Citraconic anhydride
- Purity
- 98%
- Packaging
- 25g
- Price
- $45.8
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 125318
- Product name
- Citraconic anhydride
- Purity
- 98%
- Packaging
- 100g
- Price
- $115
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 8.41321
- Product name
- Citraconic anhydride
- Purity
- for synthesis
- Packaging
- 100ml
- Price
- $95.7
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M0365
- Product name
- Citraconic Anhydride
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $24
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M0365
- Product name
- Citraconic Anhydride
- Purity
- >98.0%(GC)
- Packaging
- 100g
- Price
- $60
- Updated
- 2025/07/31
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Citraconic anhydride Chemical Properties,Usage,Production
Chemical Properties
clear colorless to very slightly yellow liquid
Uses
Reagent for alkalies, alcohols, and amines.
Uses
Citraconic anhydride is used as a monomer for specialty unsaturated polyester resins. It is used to prepare bicyclic pyrrolidines, maleimides and co- and terpolymers. It is also used for the protection of N-terminal amino acids. Further, it is involved in the preparation of clothing ping acid and its amide. In addition to this, it is selectively used for the isolation of histidyl peptides.
Uses
Versatile reagent used for the synthesis of maleimides, bicyclic pyrrolidines, and co- and terpolymers, as well as for the protection of N-terminal amino acids.
Flammability and Explosibility
Non flammable
Reactions
Citraconic anhydride is highly reactive due to the presence of anhydride groups and can undergo hydrolysis, esterification, amidation, and addition reactions.
Chemical Reactivity
Citraconic anhydride (CA) is defined as a derivative of maleic anhydride that reacts with amines to form amide linkages at alkaline pH and can be hydrolyzed at acidic pH to release citraconic acid and free the amine, making it useful for temporarily blocking amine groups during molecular modifications.
Purification Methods
Possible contamination is from the acid formed by hydrolysis. If the IR has OH bands, then reflux with Ac2O for 30minutes, evaporate, then distil the residue in a vacuum, otherwise distil in a vacuum. Store in a dry atmosphere. [Vaughan & Andersen J Am Chem Soc 77 6702 1955, Vaughan & Andersen J Org Chem 21 680 1956, Beilstein 17 H 440, 17 I 234, 17 II 448, 17 III/IV 5912, 17/11 V 65.]
Citraconic anhydride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Citraconic anhydride manufacturers
Shandong Vital Biotechnology Co., Ltd.
- Product
- Citraconic anhydride 616-02-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100tons
- Release date
- 2025-11-20
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Citraconic anhydride 616-02-4
- Price
- US $0.00/KG
- Min. Order
- 25KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-29
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- Citraconic anhydride 616-02-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-15
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