ChemicalBook > CAS DataBase List > 1,2-Dibromo-4,5-difluorobenzene

1,2-Dibromo-4,5-difluorobenzene

Product Name: 1,2-Dibromo-4,5-difluorobenzene
CAS No.: 64695-78-9
Chemical Name: 1,2-Dibromo-4,5-difluorobenzene
Synonyms: 1,2-Dibromo-4,5-difl;1,2-DIBROMO-4,5-DIFLUOROBENZENE;1,2-DibroMo-4,5-2-fluorobenzene;4,5-difluoroortho dibromobenzene;1,2-Dibromo-4,5-difluorobenzene>Benzene, 1,2-dibromo-4,5-difluoro-;1,2-Dibromo-4,5-difluorobenzene98%;1,2-Dibromo-4,5-difluorobenzene,99%;1,2-Dibromo-4,5-difluorobenzene 98%;1,2-Dibromo-4,5-difluorobenzene ISO 9001：2015 REACH
CBNumber: CB9768747
Molecular Formula: C6H2Br2F2
Formula Weight: 271.88
MOL File: 64695-78-9.mol

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1,2-Dibromo-4,5-difluorobenzene Property

Melting point:: 33-35 °C (lit.)
Boiling point:: 216.2±35.0 °C(Predicted)
Density: 2.1030 (rough estimate)
refractive index: 1.5151 (estimate)
Flash point:: 112 °F
storage temp.: Sealed in dry,Room Temperature
form: powder to lump to clear liquid
color: White or Colorless to Light yellow
Water Solubility: insoluble
BRN: 1941132
InChI: InChI=1S/C6H2Br2F2/c7-3-1-5(9)6(10)2-4(3)8/h1-2H
InChIKey: JTEZQWOKRHOKDG-UHFFFAOYSA-N
SMILES: C1(Br)=CC(F)=C(F)C=C1Br
CAS DataBase Reference: 64695-78-9(CAS DataBase Reference)
NIST Chemistry Reference: 1,2-Dibromo-4,5-difluorobenzene(64695-78-9)

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Safety

Hazard Codes: Xi
Risk Statements: 10-36/37/38
Safety Statements: 16-26-36/37/39-24/25
RIDADR: UN 1325 4.1/PG 2
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 4.1
PackingGroup: III
HS Code: 29039990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 264237
Product name: 1,2-Dibromo-4,5-difluorobenzene
Purity: 98%
Packaging: 10g
Price: $193.02
Updated: 2025/07/31

TCI Chemical

Product number: D1913
Product name: 1,2-Dibromo-4,5-difluorobenzene
Purity: >97.0%(GC)
Packaging: 5g
Price: $35
Updated: 2025/07/31

TCI Chemical

Product number: D1913
Product name: 1,2-Dibromo-4,5-difluorobenzene
Purity: >97.0%(GC)
Packaging: 25g
Price: $104
Updated: 2025/07/31

TRC

Product number: D425353
Product name: 1,2-Dibromo-4,5-difluorobenzene
Packaging: 5g
Price: $75
Updated: 2021/12/16

TRC

Product number: D425353
Product name: 1,2-Dibromo-4,5-difluorobenzene
Packaging: 500mg
Price: $45
Updated: 2021/12/16

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1,2-Dibromo-4,5-difluorobenzene Chemical Properties,Usage,Production

Chemical Properties

white crystalline low melting mass

Uses

1,2-Dibromo-4,5-difluorobenzene has been used in the preparation of:

2,2′-dibromo-4,4′,5,5′-tetrafluorobiphenyl
2-(2,3-dibromo-5,6-difluorophenyl)propan-2-ol

Synthesis

367-11-3

64695-78-9

General procedure for the synthesis of 1,2-dibromo-4,5-difluorobenzene from 1,2-difluorobenzene: First, 84 mg (1.5 mmol) of iron powder was homogeneously dispersed in 7.53 g (50 mmol) of 1,2-difluorobenzene and the temperature of the reaction system was adjusted to 20 °C. Subsequently, 18.4 g (115 mmol) of bromine was slowly added dropwise over a period of 50 min, during which the reaction temperature was maintained at about 20 °C. Upon completion of the dropwise addition, the reaction temperature was raised to 40 °C for 2 hours, followed by further raising the temperature to 50 °C to continue the reaction for 2 hours. Upon completion of the reaction, the mixture was cooled to room temperature and poured into an aqueous solution prepared from 25.2 g of sodium bicarbonate and 12.6 g of sodium sulfite dissolved in 100 mL of water. The reaction product was extracted with ethyl acetate and the organic phase was washed sequentially with water and saturated brine solution, followed by drying with magnesium sulfate. After filtration to remove the desiccant, the reaction was quantified by HPLC, which showed 94% yield of 1,2-dibromo-4,5-difluorobenzene.

References

[1] Patent: EP2940002, 2015, A1. Location in patent: Paragraph 0051; 0052
[2] Collection of Czechoslovak Chemical Communications, 1977, vol. 42, # 6, p. 2001 - 2017

1,2-Dibromo-4,5-difluorobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1,2-Dibromo-4,5-difluorobenzene manufacturers

Henan Fengda Chemical Co., Ltd

Product: 1,2-Dibromo-4,5-difluorobenzene 64695-78-9
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-25

Career Henan Chemical Co

Product: 1,2-Dibromo-4,5-difluorobenzene 64695-78-9
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-10

64695-78-9, 1,2-Dibromo-4,5-difluorobenzeneRelated Search:

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Benzene, 1,2-dibromo-4,5-difluoro-

1,2-Dibromo-4,5-difluorobenzene 98%

1,2-Dibromo-4,5-difluorobenzene98%

1,2-DIBROMO-4,5-DIFLUOROBENZENE

1,2-Dibromo-4,5-difluorobenzene,99%

1,2-Dibromo-4,5-difl

1,2-DibroMo-4,5-2-fluorobenzene

1,2-Dibromo-4,5-difluorobenzene&gt

1,2-Dibromo-4,5-difluorobenzene ISO 9001：2015 REACH

4,5-difluoroortho dibromobenzene

64695-78-9

Br2C6H2F2

Building Blocks

Aryl

Organic Building Blocks

Halogenated Hydrocarbons

Aromatic Halides (substituted)

Bromine Compounds

Fluorine Compounds

Aryl

Halogenated Hydrocarbons