1,2-Dibromo-4,5-difluorobenzene
- Product Name
- 1,2-Dibromo-4,5-difluorobenzene
- CAS No.
- 64695-78-9
- Chemical Name
- 1,2-Dibromo-4,5-difluorobenzene
- Synonyms
- 1,2-Dibromo-4,5-difl;1,2-DIBROMO-4,5-DIFLUOROBENZENE;1,2-DibroMo-4,5-2-fluorobenzene;4,5-difluoroortho dibromobenzene;1,2-Dibromo-4,5-difluorobenzene>Benzene, 1,2-dibromo-4,5-difluoro-;1,2-Dibromo-4,5-difluorobenzene98%;1,2-Dibromo-4,5-difluorobenzene,99%;1,2-Dibromo-4,5-difluorobenzene 98%;1,2-Dibromo-4,5-difluorobenzene ISO 9001：2015 REACH
- CBNumber
- CB9768747
- Molecular Formula
- C6H2Br2F2
- Formula Weight
- 271.88
- MOL File
- 64695-78-9.mol
1,2-Dibromo-4,5-difluorobenzene Property
- Melting point:
- 33-35 °C (lit.)
- Boiling point:
- 216.2±35.0 °C(Predicted)
- Density
- 2.1030 (rough estimate)
- refractive index
- 1.5151 (estimate)
- Flash point:
- 112 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to lump to clear liquid
- color
- White or Colorless to Light yellow
- Water Solubility
- insoluble
- BRN
- 1941132
- InChI
- InChI=1S/C6H2Br2F2/c7-3-1-5(9)6(10)2-4(3)8/h1-2H
- InChIKey
- JTEZQWOKRHOKDG-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC(F)=C(F)C=C1Br
- CAS DataBase Reference
- 64695-78-9(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,2-Dibromo-4,5-difluorobenzene(64695-78-9)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 10-36/37/38
- Safety Statements
- 16-26-36/37/39-24/25
- RIDADR
- UN 1325 4.1/PG 2
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 4.1
- PackingGroup
- III
- HS Code
- 29039990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 264237
- Product name
- 1,2-Dibromo-4,5-difluorobenzene
- Purity
- 98%
- Packaging
- 10g
- Price
- $193.02
- Updated
- 2025/07/31
- Product number
- D1913
- Product name
- 1,2-Dibromo-4,5-difluorobenzene
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $35
- Updated
- 2025/07/31
- Product number
- D1913
- Product name
- 1,2-Dibromo-4,5-difluorobenzene
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $104
- Updated
- 2025/07/31
- Product number
- D425353
- Product name
- 1,2-Dibromo-4,5-difluorobenzene
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- D425353
- Product name
- 1,2-Dibromo-4,5-difluorobenzene
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
1,2-Dibromo-4,5-difluorobenzene Chemical Properties,Usage,Production
Chemical Properties
white crystalline low melting mass
Uses
1,2-Dibromo-4,5-difluorobenzene has been used in the preparation of:
- 2,2′-dibromo-4,4′,5,5′-tetrafluorobiphenyl
- 2-(2,3-dibromo-5,6-difluorophenyl)propan-2-ol
Synthesis
367-11-3
64695-78-9
General procedure for the synthesis of 1,2-dibromo-4,5-difluorobenzene from 1,2-difluorobenzene: First, 84 mg (1.5 mmol) of iron powder was homogeneously dispersed in 7.53 g (50 mmol) of 1,2-difluorobenzene and the temperature of the reaction system was adjusted to 20 °C. Subsequently, 18.4 g (115 mmol) of bromine was slowly added dropwise over a period of 50 min, during which the reaction temperature was maintained at about 20 °C. Upon completion of the dropwise addition, the reaction temperature was raised to 40 °C for 2 hours, followed by further raising the temperature to 50 °C to continue the reaction for 2 hours. Upon completion of the reaction, the mixture was cooled to room temperature and poured into an aqueous solution prepared from 25.2 g of sodium bicarbonate and 12.6 g of sodium sulfite dissolved in 100 mL of water. The reaction product was extracted with ethyl acetate and the organic phase was washed sequentially with water and saturated brine solution, followed by drying with magnesium sulfate. After filtration to remove the desiccant, the reaction was quantified by HPLC, which showed 94% yield of 1,2-dibromo-4,5-difluorobenzene.
References
[1] Patent: EP2940002, 2015, A1. Location in patent: Paragraph 0051; 0052
[2] Collection of Czechoslovak Chemical Communications, 1977, vol. 42, # 6, p. 2001 - 2017
1,2-Dibromo-4,5-difluorobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
1,2-Dibromo-4,5-difluorobenzene Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
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- Country
- Europe
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View Lastest Price from 1,2-Dibromo-4,5-difluorobenzene manufacturers
- Product
- 1,2-Dibromo-4,5-difluorobenzene 64695-78-9
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25
- Product
- 1,2-Dibromo-4,5-difluorobenzene 64695-78-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-10