ChemicalBook > CAS DataBase List > Genistin

Genistin

Product Name
Genistin
CAS No.
529-59-9
Chemical Name
Genistin
Synonyms
GENISTEIN-7-O-GLUCOSIDE;GENISTEIN-7-GLUCOSIDE;genistein 7-O-β-D-glucoside;GENISTIN;NSC 5112;genistine;Genistoside;Genistin-RM;Genistin(AS);Genistin ,98%
CBNumber
CB9769395
Molecular Formula
C21H20O10
Formula Weight
432.38
MOL File
529-59-9.mol
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Genistin Property

Melting point:
254°C
alpha 
D21 -28° (c = 0.6 in 0.02N NaOH); D26 -21.4° (pyridine)
Boiling point:
256 °C
Density 
1.642±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 10 mg/mL
pka
6.12±0.20(Predicted)
form 
Solid
color 
Off-white
biological source
Glycine max (soybean)
Merck 
13,4402
BRN 
64479
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
InChIKey
ZCOLJUOHXJRHDI-CMWLGVBASA-N
LogP
0.790 (est)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
DJ3093000
F 
10
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89200
Product name
Genistin
Purity
phyproof<SUP>&#174;</SUP> Reference Substance
Packaging
25 mg
Price
$320
Updated
2025/07/31
Sigma-Aldrich
Product number
1288805
Product name
Genistin
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
30mg
Price
$1160
Updated
2025/07/31
Sigma-Aldrich
Product number
05380590
Product name
Genistin
Purity
primary reference standard
Packaging
25mg
Price
$555
Updated
2023/06/20
TCI Chemical
Product number
G0358
Product name
Genistin
Packaging
25MG
Price
$78
Updated
2025/07/31
TCI Chemical
Product number
G0358
Product name
Genistin
Packaging
100MG
Price
$212
Updated
2025/07/31
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Genistin Chemical Properties,Usage,Production

Description

Genistin is a natural isoflavone isolated from legumes, including soy and kudzu. It is a phytoestrogen, as it stimulates the growth of estrogen-dependent human breast cancer cells in vivo. Like other isoflavones, genistin promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover. It also increases bone formation in collagen matrix in vivo.

Chemical Properties

White Powder

Uses

A derivative of Genistein. Inhibitor

Uses

An isoflavone glycoside which is an inactive analog of the PTK inhibitor Genistein.

Uses

Genistin has been used for immune reactivity against influenza viruses in vitro and as an internal standard in isoflavones quantification.

Uses

Glucoside of genistein that inhibits protein tyrosine kinase

Definition

ChEBI: Genistein 7-O-beta-D-glucoside is a 7-hydroxyisoflavones 7-O-beta-D-glucoside. It is functionally related to a genistein. It is a conjugate acid of a genistein 7-O-beta-D-glucoside(1-).

General Description

Genistin belongs to the class of isoflavone glycosides generally extracted from soybeans.

Biochem/physiol Actions

Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT), with no measurable effect on mammalian or microbial DNA polymerases.

Purification Methods

Genistin is repeatedly crystallised from hot 80% EtOH/water and treated with charcoal (Nuchar) until free from saponin. The presence of saponin is detected by adding crystals to conc H2SO4 when the citron yellow colour changes to red, then purple. Pure genistin does not change colour. UV in 85% EtOH has max at 262.5nm. [Walter J Am Chem Soc 63 3273 1941, Beilstein 18 III/IV 2732.]

References

[1] YUKINOBU UCHIYAMA . Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): Baicalin and genistin[J]. Biochimica et biophysica acta. General subjects, 2005, 1725 3: Pages 298-304. DOI:10.1016/j.bbagen.2005.06.017
[2] EUN JEONG CHOI  Myeong S L  Taehee Kim. Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells[J]. Life sciences, 2007, 80 15: Pages 1403-1408. DOI:10.1016/j.lfs.2006.12.031
[3] ALESSANDRA RUSSO . Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells[J]. Journal of Nutritional Biochemistry, 2006, 17 2: Pages 103-108. DOI:10.1016/j.jnutbio.2005.05.011

Genistin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Genistin manufacturers

BINBO BIOLOGICAL CO.,LTD
Product
Genistin 529-59-9
Price
US $10.00/kg
Min. Order
1kg
Purity
60% 80% 90% 95%
Supply Ability
1000 kg
Release date
2025-01-02
Shanghai Standard Technology Co., Ltd.
Product
Genistin 529-59-9
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-14
Zhuozhou Wenxi import and Export Co., Ltd
Product
Genistin 529-59-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

529-59-9, GenistinRelated Search:

Trimethylolpropane Alkyl polyglucoside BETA-GLUCOSIDASE Genistein Baicalin Resveratrol Glycitein Taxifolin Bengenin Tris(hydroxymethyl)aminomethane Isoflavone Tectoridin 6''-O-ACETYLGENISTIN OCTYL GLUCOSIDE kakkalide Genistin GENISTIN SNAP-N-SHOOT 0.1mg/ml(P) GENISTIN(P)

  • 4',5,7-TRIHYDROXYISOFLAVONE 7-GLUCOSIDE
  • 7-O-B-D-GLUCOPRYANOSYL GENISTEIN
  • 7-O-BETA-D-GLUCOPYRANOSIDE
  • GENISTEIN-7-GLUCOSIDE
  • GENISTEIN, 7-O-BETA-D-GLUCOPYRANOSIDE
  • GENISTEIN-7-O-GLUCOSIDE
  • GENISTIN
  • GLUCOSYL-7-GENISTEIN
  • 4μ,5,7-Trihydroxyisoflavone 7-glucoside, Genistein 7-glucoside, Genistein-7-O-β-D-glucopyranoside
  • Genistin，Genistein 7-glucoside
  • 7-[(β-D-Glucopyranosyl)oxy]-4',5-dihydroxyisoflavone
  • Genistin ,98%
  • Genistin,4′,5,7-Trihydroxyisoflavone 7-glucoside, Genistein 7-glucoside, Genistein-7-O-β-D-glucopyranoside
  • Genistin (30 mg)
  • genistein,7-o-beta-d-glucoside
  • genistine
  • 7-(-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • Genistein-7--O-Glucopyranoside
  • genistin from glycine max
  • 7-(b-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4- one
  • Genistein-7-b-O-Glucopyranoside
  • Genistoside
  • NSC 5112
  • genistein 7-O-β-D-glucoside
  • Genistin - CAS 529-59-9 - Calbiochem
  • 5-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chroMen-7-ylbeta-D-glucopyranoside
  • Genistin (Genistoside)
  • 7-(beta-d-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4h-1-benzopyran-4-on
  • genistein,7-beta-d-glucopyranoside
  • 4,5,7-Trigydroxyisoflavone 7-glucoside
  • Genistin, froM soybean
  • Genistin 4',5,7-Trihydroxyisoflavone 7-glucoside
  • Genistein glucoside
  • 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one
  • 4H-1-Benzopyran-4-one, 7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-
  • GENISTIN >99%
  • GENISTIN WITH HPLC
  • -5-hydroxy-3-(4-hydroxyphenyl)-
  • Nano Liposomal Genistin
  • Genistin, 99%, from soybean
  • 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-
  • genistein7-O-β-D-glucoside
  • 4',5,7-Trihydroxyisoflavone 7-beta-D-Glucopyranoside
  • Genistin USP/EP/BP
  • Genistein-7-O-β-D-glucopyranoside
  • 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
  • 5-Hydroxy-3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
  • Genistin Supplier
  • Genistin (6CI, 7CI, 8CI)
  • Genistein 7-O-β-D-glucopyranoside, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, NSC 5112
  • Coumarin Impurity 10 (Coumarin 102)
  • Genistin(AS)
  • Genistin-RM
  • Genistin, Isoflavone glycoside
  • 529-59-9
  • 5529-29-9
  • C21H20O10
  • 43238