Genistin
- Product Name
- Genistin
- CAS No.
- 529-59-9
- Chemical Name
- Genistin
- Synonyms
- GENISTEIN-7-O-GLUCOSIDE;GENISTEIN-7-GLUCOSIDE;genistein 7-O-β-D-glucoside;GENISTIN;NSC 5112;genistine;Genistoside;Genistin ,98%;GENISTIN >99%;Genistin (30 mg)
- CBNumber
- CB9769395
- Molecular Formula
- C21H20O10
- Formula Weight
- 432.38
- MOL File
- 529-59-9.mol
Genistin Property
- Melting point:
- 254°C
- alpha
- D21 -28° (c = 0.6 in 0.02N NaOH); D26 -21.4° (pyridine)
- Boiling point:
- 256 °C
- Density
- 1.642±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 10 mg/mL
- pka
- 6.12±0.20(Predicted)
- color
- Off-white
- Merck
- 13,4402
- BRN
- 64479
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
- InChIKey
- ZCOLJUOHXJRHDI-CMWLGVBASA-N
- LogP
- 0.790 (est)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1288805
- Product name
- Genistin
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 30mg
- Price
- $1320
- Updated
- 2024/03/01
- Product number
- 05380590
- Product name
- Genistin
- Purity
- primary reference standard
- Packaging
- 25mg
- Price
- $555
- Updated
- 2023/06/20
- Product number
- J63445
- Product name
- Genistin, 99+%
- Packaging
- 100mg
- Price
- $487
- Updated
- 2024/03/01
- Product number
- 14174
- Product name
- Genistin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $61
- Updated
- 2024/03/01
- Product number
- 14174
- Product name
- Genistin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $112
- Updated
- 2024/03/01
Genistin Chemical Properties,Usage,Production
Description
Genistin is a natural isoflavone isolated from legumes, including soy and kudzu. It is a phytoestrogen, as it stimulates the growth of estrogen-
Chemical Properties
White Powder
Uses
A derivative of Genistein. Inhibitor
Uses
An isoflavone glycoside which is an inactive analog of the PTK inhibitor Genistein.
Uses
Genistin has been used for immune reactivity against influenza viruses in vitro and as an internal standard in isoflavones quantification.
Uses
Glucoside of genistein that inhibits protein tyrosine kinase
Definition
ChEBI: Genistein 7-O-beta-D-glucoside is a 7-hydroxyisoflavones 7-O-beta-D-glucoside. It is functionally related to a genistein. It is a conjugate acid of a genistein 7-O-beta-D-glucoside(1-).
General Description
Genistin belongs to the class of isoflavone glycosides generally extracted from soybeans.
Biochem/physiol Actions
Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT), with no measurable effect on mammalian or microbial DNA polymerases.
Purification Methods
Genistin is repeatedly crystallised from hot 80% EtOH/water and treated with charcoal (Nuchar) until free from saponin. The presence of saponin is detected by adding crystals to conc H2SO4 when the citron yellow colour changes to red, then purple. Pure genistin does not change colour. UV in 85% EtOH has max at 262.5nm. [Walter J Am Chem Soc 63 3273 1941, Beilstein 18 III/IV 2732.]
References
1) Uchiyama et al. (2005), Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin; Biochim. Biophys. Acta, 1725 298 2) Choi et al. (2007), Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells; Life Sci, 80 1403 3) Russo et al. (2006), Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells; J. Nutr. Biochem., 17 103
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View Lastest Price from Genistin manufacturers
- Product
- Genistin 529-59-9
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-10-14
- Product
- Genistin 529-59-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Genistin 529-59-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09