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Bis-Tris propane

Product Name
Bis-Tris propane
CAS No.
64431-96-5
Chemical Name
Bis-Tris propane
Synonyms
yehebio;B-T-Propane;BIS-TRIS PROPANE;BIS-TRIS propane 99+%;BIS-Tris Propane, ULTROL;BIS-TRIS PROPANE SIGMAULTRA;1.0 M BIS-TRIS propane pH 8.5;1.0 M BIS-TRIS propane pH 6.6;1.0 M BIS-TRIS propane pH 8.4;1.0 M BIS-TRIS propane pH 7.6
CBNumber
CB9769557
Molecular Formula
C11H26N2O6
Formula Weight
282.33
MOL File
64431-96-5.mol
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Bis-Tris propane Property

Melting point:
164-165 °C(lit.)
Boiling point:
573.3±50.0 °C(Predicted)
Density 
1.326±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
H2O: 1 M at 20 °C, clear, colorless
form 
Powder/Solid
color 
White
PH
9.0-10.1 (20-25℃, 1M in water)
pka
(1) 6.8, (2) 9.0(at 25℃)
PH Range
6.3 - 9.5
biological source
synthetic
Water Solubility 
Soluble in water.
BRN 
1786109
Major Application
diagnostic assay manufacturing
InChI
InChI=1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2
InChIKey
HHKZCCWKTZRCCL-UHFFFAOYSA-N
SMILES
C(NC(CO)(CO)CO)CCNC(CO)(CO)CO
CAS DataBase Reference
64431-96-5(CAS DataBase Reference)
Absorption
≤0.05 at 290 at 30% (w/w)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-24/25-26-36
WGK Germany 
3
HS Code 
29221980
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B6755
Product name
BIS-TRIS propane
Purity
≥99.0% (titration)
Packaging
10 kg
Price
$7150
Updated
2025/07/31
Sigma-Aldrich
Product number
B6755
Product name
BIS-TRIS propane
Purity
≥99.0% (titration)
Packaging
10 kg
Price
$7150
Updated
2025/07/31
Sigma-Aldrich
Product number
B4679
Product name
BIS-TRIS propane
Purity
BioPerformance Certified, cell culture tested, ≥99.0%
Packaging
25g
Price
$112
Updated
2025/07/31
Sigma-Aldrich
Product number
B4679
Product name
BIS-TRIS propane
Purity
BioPerformance Certified, cell culture tested, ≥99.0%
Packaging
100g
Price
$318
Updated
2025/07/31
Sigma-Aldrich
Product number
394111
Product name
BIS-TRIS propane
Purity
ULTROL<SUP>&#174;</SUP> Grade, &gt;98% (titration), non-zwitterionic buffer useful in pH range 6.3-9.5
Packaging
100 g
Price
$258
Updated
2025/07/31
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Bis-Tris propane Chemical Properties,Usage,Production

Description

BIS-TRIS Propane is Good′s buffer. It acts as ligand and forms series of dinuclear hydroxo complexes with Lanthanides(III) in the pH range 7-9. It is useful for diagnostic assay manufacturing industry.

Chemical Properties

White powder

Uses

BIS-Tris Propane is a buffer that is useful in the pH 6.3 - 9.5 range. This wide buffering range is due to its two pKa values, 6.8 (pKa1) and 9.0 (pKa2), being so close. Because of the wide buffering range, particularly down to pH 6 - 7, this buffer has been used to enhance the stability or activity of restriction enzymes, compared to Tris buffer (which is a poor buffer below pH 7.5 and has a comparatively large change in pKa with temperature).

Uses

BIS-TRIS Propane may be used in the following studies:

  • As buffer to investigate the influence of anions with varying nucleophilic properties on the autoxidation of oxymyoglobin (MbO2).
  • Purification of glucose-binding protein from membranes of Sulfolobus solfataricus.
  • As buffer during GeO2 mineralisation.

Definition

ChEBI: Bis-tris propane is a water-soluble buffer substance used for the preparation of the biochemical and biological buffer solutions; pKa = 6.8 at 20 ℃. It has a role as a buffer. It is functionally related to a member of tris.

Precautions

This trihydroxyamine analog, also known as bis-tris propane, presents as a white to almost white crystalline powder. Store in a cool and dark place. 1,3-Bis[tris(hydroxymethyl)methylamino]propane is known to be incompatible with oxidizing agents and should not be handled in their vicinity.

Bis-Tris propane Preparation Products And Raw materials

Raw materials

Preparation Products

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Bis-Tris propane Suppliers

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View Lastest Price from Bis-Tris propane manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
1,3-Bis[tris(hydroxymethyl)methylamino]propane 64431-96-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
3500kg/month
Release date
2021-09-10
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Bis-Tris propane 64431-96-5
Price
US $999.00-666.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-13
Watson Biotechnology Co.,Ltd
Product
BIS-Tris Propane 64431-96-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20MT
Release date
2024-08-01

64431-96-5, Bis-Tris propaneRelated Search:

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  • 2,2'-(1,3-Propanediyldiimino)bis[2-(hydroxymethyl)-1,3-propanediol]
  • 2,2'-[1,3-Propanediylbis(imino)]bis[2-(hydroxymethyl)-1,3-propanediol]
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