ChemicalBook > CAS DataBase List > 2-(HYDROXYMETHYL)-1,3-PROPANEDIOL

2-(HYDROXYMETHYL)-1,3-PROPANEDIOL

Product Name
2-(HYDROXYMETHYL)-1,3-PROPANEDIOL
CAS No.
4704-94-3
Chemical Name
2-(HYDROXYMETHYL)-1,3-PROPANEDIOL
Synonyms
2-(hydroxymethyl)propane-1,3-diol;TRIMETHYLOLMETHANE;trihydroxymethylmethane;Methylidynetrismethanol;(Methanetriyl)trimethanol;TRIS(HYDROXYMETHYL)METHANE;2-methylolpropane-1,3-diol;(Hydroxymethyl)propane-1,3-diol;2-(HYDROXYMETHYL)-1,3-PROPANEDIOL;2-Hydroxymethyl-1,3-propanediol 97%
CBNumber
CB7255274
Molecular Formula
C4H10O3
Formula Weight
106.12
MOL File
4704-94-3.mol
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2-(HYDROXYMETHYL)-1,3-PROPANEDIOL Property

Melting point:
63-68 °C (dec.) (lit.)
Boiling point:
158 °C(Press: 1.5 Torr)
Density 
1.213±0.06 g/cm3(Predicted)
Flash point:
89 °C
storage temp. 
Sealed in dry,Room Temperature
form 
solid
pka
14.10±0.10(Predicted)
Appearance
Off-white to light yellow Solid
BRN 
1733340
InChI
InChI=1S/C4H10O3/c5-1-4(2-6)3-7/h4-7H,1-3H2
InChIKey
SFRDXVJWXWOTEW-UHFFFAOYSA-N
SMILES
C(O)C(CO)CO
CAS DataBase Reference
4704-94-3(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
393657
Product name
2-Hydroxymethyl-1,3-propanediol
Purity
97%
Packaging
1g
Price
$178.6
Updated
2025/07/31
TCI Chemical
Product number
H1846
Product name
2-(Hydroxymethyl)propane-1,3-diol
Purity
min. 98.0 %
Packaging
1G
Price
$94
Updated
2025/07/31
TCI Chemical
Product number
H1846
Product name
2-(Hydroxymethyl)propane-1,3-diol
Purity
min. 98.0 %
Packaging
5G
Price
$282
Updated
2025/07/31
TRC
Product number
H973048
Product name
2-(Hydroxymethyl)propane-1,3-diol
Packaging
500mg
Price
$200
Updated
2021/12/16
AK Scientific
Product number
6412AB
Product name
2-Hydroxymethyl-1,3-propanediol
Packaging
250mg
Price
$97
Updated
2021/12/16
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2-(HYDROXYMETHYL)-1,3-PROPANEDIOL Chemical Properties,Usage,Production

Uses

2-(Hydroxymethyl)propane-1,3-diol is a useful reactant for the preparation of tetracyanocyclopentadienide amine salts.

Synthesis Reference(s)

Synthesis, p. 742, 1987 DOI: 10.1055/s-1987-28072

Synthesis

113967-50-3

4704-94-3

The general procedure for the synthesis of 2-hydroxymethyl-1,3-propanediol using the compound (CAS:113967-50-3) as starting material was as follows: the white powder (360 g, 0.86 mol) obtained in step (2) was dissolved in methanol (2L), followed by the addition of sodium methanolate (139 g, 2.58 mol). The reaction mixture was heated to reflux and kept for 20 hours. After completion of the reaction, the solvent was removed by evaporation. The residue was washed twice with chloroform and the organic phases were combined. The organic phase was dried over anhydrous sodium sulfate and concentrated. The concentrated product was crystallized in isobutanol to give 82 g of white powdered 2-hydroxymethyl-1,3-propanediol in 90% yield.

References

[1] Synthesis, 1987, # 8, p. 742 - 744
[2] Patent: CN108440455, 2018, A. Location in patent: Paragraph 0066; 0076-0078; 0100; 0122

2-(HYDROXYMETHYL)-1,3-PROPANEDIOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(HYDROXYMETHYL)-1,3-PROPANEDIOL Suppliers

Chongqing Maohuan Chemical Co.Ltd>
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China
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View Lastest Price from 2-(HYDROXYMETHYL)-1,3-PROPANEDIOL manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
2-(Hydroxymethyl)-1,3-propanediol 4704-94-3
Price
US $3.00-9.00/KG
Min. Order
0.01KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-21
Shaanxi Dideu Medichem Co. Ltd
Product
2-Hydroxymethyl-1,3-propanediol 4704-94-3
Price
US $1.00-22.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-08-08
Career Henan Chemical Co
Product
2-(HYDROXYMETHYL)-1,3-PROPANEDIOL 4704-94-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2018-08-15

4704-94-3, 2-(HYDROXYMETHYL)-1,3-PROPANEDIOLRelated Search:


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