ChemicalBook > CAS DataBase List > N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
- Product Name
- N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
- CAS No.
- 7365-44-8
- Chemical Name
- N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
- Synonyms
- TES;N-TRIS(HYDROXYMETHYL)METHYL-2-AMINOETHANESULFONIC ACID;Tes Buffer;TES,2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid, TES free acid;C05353;Tris TES;8-Fluoro-1;OmniPur TES;TES free acid;3-cd]indol-6-one
- CBNumber
- CB5114267
- Molecular Formula
- C6H15NO6S
- Formula Weight
- 229.25
- MOL File
- 7365-44-8.mol
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N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Property
- Melting point:
- ~225 °C (dec.)
- Density
- 1.260 (estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- H2O: 1 M at 20 °C, clear, colorless
- form
- Crystalline Powder
- color
- White
- PH Range
- 6.8 - 8.2
- PH
- 3.5-5.0 (25℃, 1M in H2O)
- pka
- 7.5(at 25℃)
- Odor
- Odorless
- Water Solubility
- SOLUBLE
- λmax
- λ: 260 nm Amax: 0.055
λ: 280 nm Amax: 0.045 - Merck
- 14,9176
- BRN
- 1957061
- InChIKey
- JOCBASBOOFNAJA-UHFFFAOYSA-N
- CAS DataBase Reference
- 7365-44-8(CAS DataBase Reference)
- EPA Substance Registry System
- Ethanesulfonic acid, 2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (7365-44-8)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-36-26
- WGK Germany
- 1
- TSCA
- Yes
- HS Code
- 29221980
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 5.05147
- Product name
- OmniPur® TES
- Purity
- TES, CAS 7365-44-8 , is a Zwitterionic buffer that is useful in the pH range of 6.8-8.2.
- Packaging
- 100G
- Price
- $176
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 5.05147
- Product name
- OmniPur® TES
- Purity
- TES, CAS 7365-44-8 , is a Zwitterionic buffer that is useful in the pH range of 6.8-8.2.
- Packaging
- 1KG
- Price
- $985
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 93359
- Product name
- TES
- Purity
- BioUltra, ≥99.5% (calc. based on dry substance, T)
- Packaging
- 25g
- Price
- $246
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 93359
- Product name
- TES
- Purity
- BioUltra, ≥99.5% (calc. based on dry substance, T)
- Packaging
- 100g
- Price
- $589
- Updated
- 2023/06/20
TCI Chemical
- Product number
- T0683
- Product name
- N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid [Good's buffer component for biological research]
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $107
- Updated
- 2024/03/01
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N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Chemical Properties,Usage,Production
Chemical Properties
White/clear crystalline powder
Uses
A structural analog to Tris buffer.
Uses
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid (TES) probably exists in solution as a zwitterion. Because the pKa is 7.4 (physiological pH) this buffer has considerable potential for a variety of biological applications. A buffer using TES free acid can be prepared by titrating the free acid (sc-206102) with sodium hydroxide to the desired pH, using about a half-equivalent of NaOH. Alternatively, solutions of equimolar TES free acid and TES sodium (sc-264384) can be mixed to attain a buffer of the desired pH. It has been shown to be toxic in vitro, but this toxicity may be due to its ability to form metal chelate complexes that are toxic for cells. TES is a commonly used biological buffering agent.
Definition
ChEBI: N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid is a Good's buffer substance, pKa = 7.5 at 20 ℃. It is a member of ethanolamines, an amino sulfonic acid and a TES. It is functionally related to a taurine. It is a tautomer of a N-tris(hydroxymethyl)methyl-2-ammonioethanesulfonate.
Purification Methods
Crystallise the acid from hot EtOH containing a little water.
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
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N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Suppliers
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View Lastest Price from N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid manufacturers
hebei hongtan Biotechnology Co., Ltd
- Product
- 2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid 7365-44-8
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000
- Release date
- 2024-03-28
Suzhou Genemill Biotechnology Co.,Ltd
- Product
- TES 7365-44-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99.5%
- Supply Ability
- 1000tons
- Release date
- 2023-09-14
Suzhou Genemill Biotechnology Co.,Ltd
- Product
- TES-N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid 7365-44-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99.5%
- Supply Ability
- 1000tons
- Release date
- 2023-10-23
7365-44-8, N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic AcidRelated Search:
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N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
Tris(hydroxymethyl)aminomethane
N-TRIS(HYDROXYMETHYL)METHYL-2-AMINOETHANESULFONIC ACID-D15
2-([2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]AMINO)ETHANESULFONIC ACID HEMISODIUM SALT