ChemicalBook > CAS DataBase List > 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

Product Name
1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CAS No.
869497-75-6
Chemical Name
1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
Synonyms
VUF 6002;VUF6002 maleate;VUF 6002 maleate;JNJ 10191584 MALEATE;JNJ 10191584 maleate salt;JNJ 10191584 maleate (VUF 6002);1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CBNumber
CB9844434
Molecular Formula
C17H19ClN4O5
Formula Weight
394.80956
MOL File
869497-75-6.mol
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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Property

storage temp. 
Desiccate at RT
solubility 
DMSO: ≥10mg/mL
form 
powder
color 
off-white to light tan
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
J3830
Product name
JNJ 10191584 maleate salt
Purity
≥98% (HPLC)
Packaging
5mg
Price
$105
Updated
2022/05/15
Sigma-Aldrich
Product number
J3830
Product name
JNJ 10191584 maleate salt
Purity
≥98% (HPLC)
Packaging
25mg
Price
$573
Updated
2022/05/15
Alfa Aesar
Product number
J65433
Product name
JNJ 10191584 maleate
Packaging
50mg
Price
$229
Updated
2021/12/16
Alfa Aesar
Product number
J65433
Product name
JNJ 10191584 maleate
Packaging
10mg
Price
$57.2
Updated
2021/12/16
Tocris
Product number
2441
Product name
JNJ 10191584 maleate
Purity
≥99%(HPLC)
Packaging
10
Price
$152
Updated
2021/12/16
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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Chemical Properties,Usage,Production

Uses

A highly selective histamine H4 receptor silent antagonist

Biological Activity

Highly selective histamine H 4 receptor silent antagonist; binds with high affinity to the human H 4 receptor (K i = 26 nM) and is > 540-fold selective over the H 3 receptor (K i = 14.1 μ M). In vitro, inhibits mast cell and eosinophil chemotaxis with IC 50 values of 138 and 530 nM respectively. Orally active in vivo .

storage

room temperature (desiccate)

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Suppliers

China 18 Germany 2 United Kingdom 2 United States 7 Global 29
VDM Biochemicals
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0330-2528181
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0330-2528171
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sales@vdmbio.com
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United States
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EMMX Biotechnology LLC
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888-539-0666
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888-539-0666
Email
info@emmx.com
Country
United States
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
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Aladdin Scientific
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+1-+1(833)-552-7181
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sales@aladdinsci.com
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United States
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ApexBio Technology
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sales@apexbt.com
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United States
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United States Biological
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chemicals@usbio.net
Country
United States
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Riedel-de Haen AG
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869497-75-6, 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATERelated Search:

(6-CHLORO-1H-BENZOIMIDAZOL-2-YL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE 1H-BENZIMIDAZOLE-2-CARBOXALDEHYDE, 5-CHLORO-

  • JNJ 10191584 MALEATE
  • 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
  • VUF 6002
  • JNJ 10191584 maleate salt
  • VUF 6002 maleate
  • VUF6002 maleate
  • JNJ 10191584 maleate (VUF 6002)
  • 869497-75-6
  • C13H15ClN4OC4H4O4
  • Other Enzyme Inhibitors and Activators.
  • Histamine
  • Other enzyme inhibitors and activators
  • Histamine receptor