ChemicalBook > CAS DataBase List > 1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE

1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE

Application

Product Name: 1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE
CAS No.: 5655-01-6
Chemical Name: 1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE
Synonyms: 1,4,6-Triazainden-7(6H)-one;1H-pyrrolo[3,2-d]pyriMidin-4(5H)-one;1H,4H,5H-pyrrolo[3,2-d]pyriMidin-4-one;1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE;4H-Pyrrolo3,2-dpyrimidin-4-one, 1,5-dihydro-;1,5-Dihydro-4H-pyrrolo[3,2-d]pyriMidine-4-one;4H-Pyrrolo[3,2-d]pyriMidin-4-one, 3,5-dihydro-;4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1,5-dihydro- (8CI,9CI);1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one(3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one)
CBNumber: CB9844661
Molecular Formula: C6H5N3O
Formula Weight: 135.12
MOL File: 5655-01-6.mol

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1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE Property

Melting point:: >300℃
Boiling point:: 473.1±18.0 °C(Predicted)
Density: 1.62
storage temp.: Sealed in dry,Room Temperature
pka: 12.02±0.20(Predicted)
Appearance: Light brown to brown Solid

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Safety

HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P999980
Product name: 1H-Pyrrolo[3,2-D]pyrimidin-4(5H)-one
Packaging: 50mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-M1569
Product name: 1,5-Dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Purity: 99.94%
Packaging: 1g
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD153605
Product name: 1,5-Dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Packaging: 500mg
Price: $80
Updated: 2021/12/16

Matrix Scientific

Product number: 057906
Product name: 3H-Pyrrolo[3,2-d]pyrimidin-4(5H)-one
Packaging: 500mg
Price: $101
Updated: 2021/12/16

AK Scientific

Product number: W7018
Product name: 1,5-Dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Packaging: 1g
Price: $122
Updated: 2021/12/16

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1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE Chemical Properties,Usage,Production

Application

1,5-Dihydro-4H-pyrrolo[3,2-D]pyrimidin-4-one can be used as an organic synthesis intermediate and a pharmaceutical intermediate, mainly in laboratory research and development processes and chemical production processes.

Synthesis

3473-63-0

252932-48-2

5655-01-6

Step C: Pyrrolo[3,2-D]pyrimidin-4-one (23 g) prepared in Step B was dissolved in ethanol (210 ml) followed by addition of formamidine acetate (23.3 g). The reaction mixture was placed in an oil bath at 100-105°C and heated to reflux for 16 hours. After completion of the reaction, the mixture was cooled to room temperature and the precipitate precipitated was collected by filtration. The precipitate was washed repeatedly with ethanol until the washings were colorless. Finally, the precipitate was dried under high vacuum (HV) conditions to give a gray solid product (15.3 g, 75% yield, molecular ion peak MH+ = 136 by mass spectrometry).

References

[1] Patent: WO2008/63669, 2008, A1. Location in patent: Page/Page column 67
[2] Patent: US2012/202785, 2012, A1. Location in patent: Page/Page column 129
[3] Journal of Organic Chemistry, 1999, vol. 64, # 22, p. 8411 - 8412
[4] Patent: US6693193, 2004, B1. Location in patent: Page column 15-17
[5] Patent: WO2016/187183, 2016, A1. Location in patent: Paragraph 0062

1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE Suppliers

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View Lastest Price from 1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE manufacturers

Career Henan Chemical Co

Product: 1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE 5655-01-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-21

5655-01-6, 1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONERelated Search:

PYRIDO[2,3-D]PYRIMIDIN-4(1H)-ONE YRIDO[4,3-D]PYRIMIDINE-6(5H)-CARBOXYLIC ACID, 2-AMINO-7,8-DIHYDRO-, 1,1-DIMETHYLETHYL ESTER PYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE Pyrrolo[1,2-a]pyrazine Pyrido[2,3-b]pyrazine 7-BROMO-1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE Forodesine 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) 8-METHOXYPYRIMIDINO[5,4-B]INDOL-4(3H)-ONE 1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE CI 972 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 7-amino-1,5-dihydro- (9CI) Peldesine 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-DIMETHYLAMINOMETHYLENE-7-DEAZA-2'-DEOXYGUANOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE 9-deaza-9-(3-thienylmethyl)guanine ETHYL 4,5-DIHYDRO-4-OXO-1H-PYRROLO[3,2-D]PYRIMIDINE-7-CARBOXYLATE 3,5-DIHYDRO-7-NITRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE 9-DEAZA-2'-DEOXYGUANOSINE (2-AMINO-7-(BETA-D-2-DEOXYRIBOFURANOSYL)PYRROLO[3,2-D]PYRIMIDIN-4-ONE)

1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE

4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1,5-dihydro- (8CI,9CI)

4H-Pyrrolo3,2-dpyrimidin-4-one, 1,5-dihydro-

1H-pyrrolo[3,2-d]pyriMidin-4(5H)-one

1H,4H,5H-pyrrolo[3,2-d]pyriMidin-4-one

4H-Pyrrolo[3,2-d]pyriMidin-4-one, 3,5-dihydro-

1,5-Dihydro-4H-pyrrolo[3,2-d]pyriMidine-4-one

1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one(3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one)

1,4,6-Triazainden-7(6H)-one

5655-01-6

Heterocycle-Pyrimidine series

PYRIMIDINE