2-Bromobutane Property

Melting point:

-112 °C

Boiling point:

91 °C(lit.)

Density 

1.255 g/mL at 25 °C(lit.)

vapor pressure 

70 hPa (20 °C)

refractive index 

n20/D 1.4369(lit.)

Flash point:

70 °F

storage temp. 

Store at +2°C to +8°C.

solubility 

<1g/l

form 

Liquid

color 

Clear colorless to yellow-brown

explosive limit

2.6-6.6%(V)

Water Solubility 

insoluble

Merck 

14,1554

BRN 

505949

Dielectric constant

8.6400000000000006

Stability:

Stable. Flammable. Incompatible with strong oxidizing agents.

InChIKey

UPSXAPQYNGXVBF-UHFFFAOYSA-N

LogP

3 at 35℃ and pH7

CAS DataBase Reference

78-76-2(CAS DataBase Reference)

NIST Chemistry Reference

Butane, 2-bromo-(78-76-2)

EPA Substance Registry System

Butane, 2-bromo- (78-76-2)

Safety

Hazard Codes 

F,Xi

Risk Statements 

11-36/37/38-10-52

Safety Statements 

16-23-24/25-37/39-26

RIDADR 

UN 2339 3/PG 2

WGK Germany 

2

RTECS 

EJ6228000

Autoignition Temperature

265 °C

Hazard Note 

Irritant/Highly Flammable

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

HS Code 

29033036

Hazardous Substances Data

78-76-2(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P273Avoid release to the environment.

2-Bromobutane Chemical Properties,Usage,Production

Chemical Properties

colourless liquid with a pleasant odour

Uses

2-Bromobutane is utilized in the synthesis of non-nucleosides. It is used as a solvent as well as an intermediate in organic synthesis. It is an important raw material used to prepare Grignard reagent by reacting with magnesium. Further, it reacts with hydrocyanic acid to prepare sodium salt to get (+-)-sec-butyl cyanide. It is an important raw material used to prepare Grignard reagent by reacting with magnesium.

Uses

2-Bromobutane is used in the various organic synthesis, existing as a grignard reagent.

General Description

A colorless to pale-yellow colored liquid with a pleasant odor. Flash point 65°F. Insoluble in water and denser than water. Vapors are heavier than air and may be narcotic in high concentrations. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Halogenated aliphatic compounds, such as 2-Bromobutane , are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. Gives toxic fumes of bromine when burned.

Hazard

Narcotic in high concentration. Flammable, dangerous fire risk.

Health Hazard

Irritating to eyes, nose, throat, upper respiratory tract, and skin. Symptoms of exposure include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.

Safety Profile

Narcotic in high concentrations. Questionable carcinogen with experimental neoplastigenic data. See also BROMIDES and CHLORINATED HYDROCARBONS, ALIPHATIC. Flammable liquid. Dangerous fire hazard when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Br-; can react with oxidzing materials. To fight fire, use water, spray or mist, foam, Co2, dry chemical.

Purification Methods

Wash 2-bromobutane with conc HCl, water, 10% aqueous NaHSO3, and then water. Dry it with CaCl2, Na2SO4 or anhydrous K2CO3, and fractionally distil it through a 1m glass helices packed column. [Beilstein 1 IV 261.]