Epitiostanol

Product Name: Epitiostanol
CAS No.: 2363-58-8
Chemical Name: Epitiostanol
Synonyms: 10275S;Thiodrol;NSC 194684;Epitiostano;Epitiostanol;EPitostsanol;Epithiostanol;Epitiostanol RS;Epithioandrostanol;Epitiostanol USP/EP/BP
CBNumber: CB9875137
Molecular Formula: C19H30OS
Formula Weight: 306.51
MOL File: 2363-58-8.mol

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Epitiostanol Property

Melting point:: 127-128°
alpha: D27.5 +24.4° (c = 1.054 in chloroform)
Boiling point:: 417.1°C (rough estimate)
Density: 1.0122 (rough estimate)
refractive index: 1.5700 (estimate)
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 15.10±0.60(Predicted)
color: White to Off-White
Water Solubility: 1.2mg/L(37 ºC)

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Safety

Toxicity: LD50 in mice, rats (mg/kg): 1, 5 i.p. (Minesita, p 805)

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Hazard and Precautionary Statements (GHS)

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Epitiostanol Chemical Properties,Usage,Production

Originator

Thiodrol,Shionogi,Japan,1977

Uses

An anabolic steroid that exhibits androgenic, myogenic, anabolic, anticatabolic, progestational, deciduomatogenic, and antiestrogenic activities. An anti-estrogen with anti-mammry cancer agent.

Definition

ChEBI: Epitiostanol is an organic molecular entity.

Manufacturing Process

A solution of 2β-thiocyanato-3α-methanesulfonyloxy-5α-androstan-17β-ol 17- acetate (0.82 part by weight) and potassium hydroxide (0.9 part by weight) in diglyme (20 parts by volume) is refluxed on a water bath for 24 hours while stirring. To the reaction mixture, there is added water, and the separated substance is collected by filtration and crystallized from hexane to give 2β,3β- epithio-5α-androstan-17β-ol (0.60 part by weight) as crystals melting at 132.5°C to 134°C.

Therapeutic Function

Antineoplastic

Epitiostanol Preparation Products And Raw materials

Raw materials

Preparation Products

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Epitiostanol Suppliers

Canada 1 China 17 Japan 1 United States 2 Global 21

Chembest Research Laboratories Limited

Tel: +86-21-20908456
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ProdList: 6005
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Chemsky (shanghai) International Co.,Ltd

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Chizhou Kailong Import and Export Trade Co., Ltd.

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Raw material medicin reagent co.,Ltd

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Zhejiang J&C Biological Technology Co.,Limited

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Shaanxi Dideu Medichem Co. Ltd

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Fax: +86-29-88380327
Email: 1026@dideu.com
Country: China
ProdList: 7724
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CONIER CHEM AND PHARMA LIMITED

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career henan chemical co

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Wuhan Yanzhe Technology Co., Ltd

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Energy Chemical

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Shanghai Tachizaki Biomedical Research Center

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Shanghai Hao Zhun Biological Technology Co., Ltd.

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Debye Scientific Corporation

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Lanospharma Laboratories Co.,Ltd

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Hangzhou Deli Chemical Co., Ltd

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Taizhou Baida Pharmaceutical Co., Ltd

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View Lastest Price from Epitiostanol manufacturers

Career Henan Chemical Co

Product: Epitiostanol 2363-58-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2020-02-12

2363-58-8, EpitiostanolRelated Search:

Clerosterol LUMISTEROL 9-beta,10-alpha-ergosta-5,7,22-trien-3-beta-ol Wood sterols EPICHOLESTEROL STIGMASTEROL Sterol Vegetable alcohol DI-N-OCTYL SULFIDE ETHYLENE SULFIDE Epitiostanol 11-Mercapto-1-undecanol Mepitiostane CYCLOHEXENE SULFIDE 16-MERCAPTO-1-HEXADECANOL PROPYLENE SULFIDE TERT-TETRADECANETHIOL THIEPAN

2alpha,3alpha-Epithio-5alpha-androstan-17beta-ol

Epithioandrostanol

Epitiostanol

10275S

2,3-Epithio-1H-cyclopenta[a]phenanthrene, androstan-17-ol deriv.

2α,3α-Epithio-5α-androstan-17β-ol

5α-Androstan-17β-ol, 2α,3α-epithio- (7CI, 8CI)

Androstan-17-ol, 2,3-epithio-, (2α,3α,5α,17β)-

Epithiostanol

NSC 194684

Thiodrol

2,3-Epithio-1H-cyclopenta[a]phenanthrene

(2α,3α,5α,17β)-2,3-Epithioandrostan-17-ol

Androstan-17-ol,2,3-epithio-, (2a,3a,5a,17b)-

Epitiostano

EPitostsanol

Epitiostanol (Contains up to 15% 3α,4α-Epithioandrostan Isomer)

Epitiostanol RS

Epitiostanol USP/EP/BP

2363-58-8

C19H30OS

Inhiitors

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids

Sulfur & Selenium Compounds