ChemicalBook > CAS DataBase List > Epitiostanol

Epitiostanol

Product Name
Epitiostanol
CAS No.
2363-58-8
Chemical Name
Epitiostanol
Synonyms
10275S;Thiodrol;NSC 194684;Epitiostano;Epitiostanol;EPitostsanol;Epithiostanol;Epitiostanol RS;Epithioandrostanol;Epitiostanol USP/EP/BP
CBNumber
CB9875137
Molecular Formula
C19H30OS
Formula Weight
306.51
MOL File
2363-58-8.mol
More
Less

Epitiostanol Property

Melting point:
127-128°
alpha 
D27.5 +24.4° (c = 1.054 in chloroform)
Boiling point:
417.1°C (rough estimate)
Density 
1.0122 (rough estimate)
refractive index 
1.5700 (estimate)
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
15.10±0.60(Predicted)
color 
White to Off-White
Water Solubility 
1.2mg/L(37 ºC)
More
Less

Safety

Toxicity
LD50 in mice, rats (mg/kg): 1, 5 i.p. (Minesita, p 805)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

Epitiostanol Chemical Properties,Usage,Production

Originator

Thiodrol,Shionogi,Japan,1977

Uses

An anabolic steroid that exhibits androgenic, myogenic, anabolic, anticatabolic, progestational, deciduomatogenic, and antiestrogenic activities. An anti-estrogen with anti-mammry cancer agent.

Definition

ChEBI: Epitiostanol is an organic molecular entity.

Manufacturing Process

A solution of 2β-thiocyanato-3α-methanesulfonyloxy-5α-androstan-17β-ol 17- acetate (0.82 part by weight) and potassium hydroxide (0.9 part by weight) in diglyme (20 parts by volume) is refluxed on a water bath for 24 hours while stirring. To the reaction mixture, there is added water, and the separated substance is collected by filtration and crystallized from hexane to give 2β,3β- epithio-5α-androstan-17β-ol (0.60 part by weight) as crystals melting at 132.5°C to 134°C.

Therapeutic Function

Antineoplastic

Epitiostanol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Epitiostanol Suppliers

Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
7724
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49374
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29811
Advantage
58
Wuhan Yanzhe Technology Co., Ltd
Tel
15527250409
Fax
QQ:2692360204
Email
wenhaotian12@163.com
Country
China
ProdList
4495
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
More
Less

View Lastest Price from Epitiostanol manufacturers

Career Henan Chemical Co
Product
Epitiostanol 2363-58-8
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-02-12

2363-58-8, EpitiostanolRelated Search:


  • 2alpha,3alpha-Epithio-5alpha-androstan-17beta-ol
  • Epithioandrostanol
  • Epitiostanol
  • 10275S
  • 2,3-Epithio-1H-cyclopenta[a]phenanthrene, androstan-17-ol deriv.
  • 2α,3α-Epithio-5α-androstan-17β-ol
  • 5α-Androstan-17β-ol, 2α,3α-epithio- (7CI, 8CI)
  • Androstan-17-ol, 2,3-epithio-, (2α,3α,5α,17β)-
  • Epithiostanol
  • NSC 194684
  • Thiodrol
  • 2,3-Epithio-1H-cyclopenta[a]phenanthrene
  • (2α,3α,5α,17β)-2,3-Epithioandrostan-17-ol
  • Androstan-17-ol,2,3-epithio-, (2a,3a,5a,17b)-
  • Epitiostano
  • EPitostsanol
  • Epitiostanol (Contains up to 15% 3α,4α-Epithioandrostan Isomer)
  • Epitiostanol RS
  • Epitiostanol USP/EP/BP
  • 2363-58-8
  • C19H30OS
  • Inhiitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • Sulfur & Selenium Compounds