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proquazone

Product Name
proquazone
CAS No.
22760-18-5
Chemical Name
proquazone
Synonyms
43-715;Arthrex;Biarsan;Biarison;SaH-43-715;proquazone;Proquazona;Proquazonum;Sandoz-43-715;7-methyl-4-phenyl-1-propan-2-ylquinazolin-2-one
CBNumber
CB9880256
Molecular Formula
C18H18N2O
Formula Weight
278.35
MOL File
22760-18-5.mol
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proquazone Property

Melting point:
137-138°
Boiling point:
436.12°C (rough estimate)
Density 
1.1707 (rough estimate)
refractive index 
1.5700 (estimate)
pka
0.74±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P839145
Product name
Proquazone
Packaging
50mg
Price
$1100
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012353
Product name
PROQUAZONE
Purity
95.00%
Packaging
5MG
Price
$499.39
Updated
2021/12/16
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proquazone Chemical Properties,Usage,Production

Uses

Anti-inflammatory.

Uses

Proquazone is a non-steroidal anti-inflammatory drug.

Definition

ChEBI: Proquazone is a member of pyrimidines.

brand name

Arthrex (Novartis), Biarison (Swiss-Pharma, Egypt; Biochemie, Austria; ICN Alkaloida, Hungary; Sandoz, Finland, Turkey).

Clinical Use

Proquazone has been used successfully to treat rheumatoid polyarthritis. At 900 mg/d it is comparable in effect to 150 mg/d of indomethacin. Gastrointestinal disturbances are the principal adverse effects observed with its use.

Synthesis

Synthesis: proquazone is prepared by the alkylation of 2-amino-4-methylbenzophenone with 2-iodopropane in the presence of sodium carbonate to give 4-methyl-2-[(1- methylethyl)amino]benzophenone, which is condensed with urethane in the presence of zinc chloride at 190 ?C.

proquazone Preparation Products And Raw materials

Raw materials

Preparation Products

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proquazone Suppliers

Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15396
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19994
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49323
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
17691182729 18161915376
Email
1046@dideu.com
Country
China
ProdList
10010
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24131
Advantage
58
Shanghai Haohong Scientific Co., Ltd.
Tel
400-400-8210725
Email
malulu@leyan.com
Country
China
ProdList
40041
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
4030
Advantage
58

22760-18-5, proquazone Related Search:


  • 43-715
  • Biarison
  • Biarsan
  • SaH-43-715
  • Sandoz-43-715
  • 7-Methyl-1-(1-methylethyl)-4-phenyl-2(1H)-quinazolinone
  • proquazone
  • 2(1H)-Quinazolinone, 7-methyl-1-(1-methylethyl)-4-phenyl-
  • 7-methyl-4-phenyl-1-propan-2-ylquinazolin-2-one
  • Arthrex
  • Proquazona
  • Proquazonum
  • 22760-18-5