ChemicalBook > CAS DataBase List > 9,11β-Epoxy-17-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-diene-21-yl Acetate

9,11β-Epoxy-17-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-diene-21-yl Acetate

Product Name
9,11β-Epoxy-17-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-diene-21-yl Acetate
CAS No.
912-38-9
Chemical Name
9,11β-Epoxy-17-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-diene-21-yl Acetate
Synonyms
21-Acetyloxy-9β,11β-epoxy-17-hydroxy-16β-methylpregna-1,4-diene-3,20-dione;Betamethasone Impurity 18;Betamethasone Acetate Impurity;Betamethasone Acetate - Impurity D;Betamethasone Acetate EP Impurity D;21-O-Acetyl Betamethasone 9, 11-Epoxide;Betamethasone Impurity 21（Betamethasone Acetate EP Impurity D）;Betamethasone Impurity 18 (Desoximetasone Beta Methyl Epoxide 21-Acetate);9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-acetate;9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-Acetate
CBNumber
CB9896352
Molecular Formula
C24H30O6
Formula Weight
414.4914
MOL File
912-38-9.mol
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9,11β-Epoxy-17-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-diene-21-yl Acetate Property

Melting point:
198-203°C
Boiling point:
575.1±50.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
12.51±0.70(Predicted)
color 
White
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Safety

HS Code 
2937290000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
E589185
Product name
9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione21-Acetate
Packaging
1g
Price
$1165
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
SHG0007045
Product name
9-BETA,11-BETA-EPOXY-17,21-DIHYDROXY-16-BETA-METHYLPREGNA-1,4-DIENE-3,20-DIONE-21-ACETATE
Purity
95.00%
Packaging
5MG
Price
$502.79
Updated
2021/12/16
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9,11β-Epoxy-17-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-diene-21-yl Acetate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-Acetate is an intermediate in the production of Betamethasone (B327000), which is a glucocorticoid used as an anti-inflammatory agent.

9,11β-Epoxy-17-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-diene-21-yl Acetate Preparation Products And Raw materials

Raw materials

Progesterone Ethylene glycol Methyl bromide

Preparation Products

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9,11β-Epoxy-17-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-diene-21-yl Acetate Suppliers

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912-38-9, 9,11β-Epoxy-17-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-diene-21-yl AcetateRelated Search:

Betamethasone Impurity 35 9-Bromo-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-21-acetate 11-Keto Betamethasone Betamethasone 21-phosphate disodium Betamethasone Impurity 36 Betamethasone Valerate EP Impurity I Betamethasone 17,21-dipropionate 9-Fluoro-11β,17,21-trihydroxy-16β-Methylpregna-1,4-diene-3,20-dione 21-Methanesulfonate 17-Propionate 11alpha,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione TUIYCBORCUOUBA-DEGNENOVSA-N Betamethasone 21-Acetate-17-propionate Betamethasone EP Impurity I 6-Bromo-betamethasone 17,21-Dipropionate Betamethasone Impurity 38 Beclomethasone dipropionate Betamethasone Impurity 16 Betamethasone Acetate EP Impurity C Betamethasone-17-ketone

  • (9β)-9,11β-Epoxy-16β-methyl-17,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate
  • 21-Acetyloxy-9β,11β-epoxy-17-hydroxy-16β-methylpregna-1,4-diene-3,20-dione
  • beta,11beta-Epoxy-17,21-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-acetate
  • Betamethasone Acetate EP Impurity D
  • 9beta,11beta-epoxy-17,21-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-acetate
  • 9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-acetate
  • Betamethasone Impurity 18
  • Betamethasone Impurity 21（Betamethasone Acetate EP Impurity D）
  • Betamethasone Acetate impurity 2/Betamethasone Acetate EP Impurity D/9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-Acetate
  • Betamethasone Impurity 18 (Desoximetasone Beta Methyl Epoxide 21-Acetate)
  • 21-O-Acetyl Betamethasone 9, 11-Epoxide
  • 9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-Acetate
  • Betamethasone Acetate - Impurity D
  • 9β,11β-epoxy-17α,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-epoxy-17-hydroxy-16-methyl-, (9β,11β,16β)-
  • 9,11beta-Epoxy-17-hydroxy-16beta-methyl-3,20-dioxo-9beta-pregna-1,4-diene 21-Acetate
  • Betamethasone Acetate Impurity
  • Betamethasone Acetate EP Impurity D (Betamethasone Acetate USP Related Compound D)
  • (9β,11β,16β)-21-(Acetyloxy)-9,11-epoxy-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
  • 912-38-9
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids