carbamoyl chloride
- Product Name
- carbamoyl chloride
- CAS No.
- 463-72-9
- Chemical Name
- carbamoyl chloride
- Synonyms
- carbamic chloride;carbamyl chloride;Urea chloride;chloroformamide;carbamoyl chloride;N-Carbamic chloride;Carbaminoyl chloride;Carbamic chloride (9CI);Cariprazine Impurity 18;Methylparaben Impurity 18
- CBNumber
- CB9921638
- Molecular Formula
- CH2ClNO
- Formula Weight
- 79.49
- MOL File
- 463-72-9.mol
carbamoyl chloride Property
- Melting point:
- 90℃
- Boiling point:
- bp 61-62° (decompn)
- Density
- 1.3273 (rough estimate)
- refractive index
- 1.4480 (estimate)
- pka
- 11.60±0.50(Predicted)
N-Bromosuccinimide Price
- Product number
- HCH0037091
- Product name
- CARBAMOYL CHLORIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $736.05
- Updated
- 2021/12/16
- Product number
- HCH0037091
- Product name
- CARBAMOYL CHLORIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $2381.31
- Updated
- 2021/12/16
carbamoyl chloride Chemical Properties,Usage,Production
Chemical Properties
Carbamoyl chloride, H2N – COCl, is unstable; it may be stabilized by Lewis acids (e.g., aluminum chloride) as adducts and in this form can be used in the Friedel-Crafts acylation of arenes. Since many of the monosubstituted carbamoyl chlorides also deteriorate on storage, the corresponding isocyanates are used instead. Disubstituted carbamoyl chlorides are stable and can be stored for prolonged periods.
Physical properties
The simple carbamoyl chlorides are colorless liquids or solids, usually with pungent odor.
Uses
Carbamoyl chloride can be used as an intermediate for carbamate pesticides.
Uses
Carbamoyl chlorides are intermediates with many uses. Of primary industrial importance are the reactions with alcohols, phenols, and oximes to give carbamic acid esters; with thiols (mercaptans) to give thiocarbamates; with amines and hydroxylamines to give substituted ureas; and with imidazoles and triazoles to give carbamoyl azoles.
Definition
ChEBI: Carbamyl chloride is an organonitrogen compound.
Synthesis
Carbamoyl chloride can be synthesized from methylamine and phosgene at 200-240℃.