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Diethylcarbamyl chloride

Product Name
Diethylcarbamyl chloride
CAS No.
88-10-8
Chemical Name
Diethylcarbamyl chloride
Synonyms
Diethylcarbamic chloride;DIETHYLCARBAMOYL CHLORIDE;DECC;N,N-Diethylcarbamoyl chloride;N, 97.0%(GC&T;N, 97.0%(GC&T;);Diethylcarbamyl chlo;diethylchloroformamide;diethyl-carbamicchlorid;diethylcarbamicchloride
CBNumber
CB8275909
Molecular Formula
C5H10ClNO
Formula Weight
135.59
MOL File
88-10-8.mol
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Diethylcarbamyl chloride Property

Melting point:
−32 °C(lit.)
Boiling point:
117-123 °C133 mm Hg(lit.)
Density 
1.07 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.451(lit.)
Flash point:
167 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Soluble), Methanol (Slightly)
form 
Liquid
pka
-1.85±0.70(Predicted)
color 
Clear
Specific Gravity
1.070
Water Solubility 
HYDROLYSIS
Sensitive 
Moisture Sensitive
BRN 
506687
Stability:
Moisture Sensitive
InChIKey
OFCCYDUUBNUJIB-UHFFFAOYSA-N
CAS DataBase Reference
88-10-8(CAS DataBase Reference)
NIST Chemistry Reference
Carbamic chloride, diethyl-(88-10-8)
EPA Substance Registry System
Diethylcarbamoyl chloride (88-10-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/22-36/37/38-40
Safety Statements 
26-36/37
RIDADR 
UN 3265 8/PG 3
WGK Germany 
1
RTECS 
FD4025000
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29241990
Hazardous Substances Data
88-10-8(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D91403
Product name
Diethylcarbamoyl chloride
Purity
97%
Packaging
5g
Price
$25
Updated
2023/01/07
Sigma-Aldrich
Product number
D91403
Product name
Diethylcarbamoyl chloride
Purity
97%
Packaging
100g
Price
$83.8
Updated
2023/01/07
TCI Chemical
Product number
D0482
Product name
Diethylcarbamoyl Chloride
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$23
Updated
2024/03/01
TCI Chemical
Product number
D0482
Product name
Diethylcarbamoyl Chloride
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$53
Updated
2024/03/01
Alfa Aesar
Product number
A15701
Product name
Diethylcarbamyl chloride, 98%
Packaging
25g
Price
$17.65
Updated
2024/03/01
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Diethylcarbamyl chloride Chemical Properties,Usage,Production

Description

Diethylcarbamoyl chloride is a colorless liquid.Molecular weight=135.61; Boiling point=186-190℃;Melting point=244; Flash point=163-172℃. HazardIdentification (based on NFPA-704 M Rating System):Health 2, Flammability 1, Reactivity 2. Soluble in water(reactive).

Chemical Properties

clear yellow to brownish liquid

Uses

It is used in the production of pharma ingredients. It is a reagent in the synthesis of S-Methyl-N,N-diethylthiocarbamate Sulfoxide, which is an oxygenated metabolite of Disulfiram (Antabuse) that is capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase.

Toxicology

The median lethal dose (LD50) upon oral administration to rats is about 200 mg/kg. The compound is irritating to skin and eyes. The inhalation of an atmosphere saturated with its vapors at 20℃ is lethal to rats after 3 h. Diethylcarbamoyl chloride has proved to be mutagenic on E. coli strains in mutagenicity tests. It is weakly mutagenic in high doses in the Ames test. In view of these results and on account of the structural similarity to dimethylcarbamoyl chloride, a carcinogenic potential cannot be ruled out. The MAK commission has listed this substance in group III B.

Safety Profile

Suspected carcinogen with experimental carcinogenic data. Moderately toxic by intraperitoneal route. Mutation data reported. Reacts with water or steam to produce toxic and corrosive fumes. When heated to decomposition it emits highly toxic fumes of Cl and NOx. See also CARBATMATES and CHLORIDES.

Potential Exposure

Diethylcarbamazine citrate, a carbamate anthelmintic (working agent), used in the synthesis ofpharmaceuticals.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. If victim is conscious, administer water ormilk. Do not induce vomiting.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from oxidizers and reducing agents.Where possible, automatically pump liquid from drums orother storage containers to process containers. A regulated,marked area should be established where this chemical ishandled, used, or stored in compliance with OSHAStandard 1910.1045.

Shipping

Toxic liquids, water-reactive, n.o.s. require a labelof “POISONOUS/TOXIC MATERIALS, DANGEROUSWHEN WET.” They fall in Hazard Class 6.1.

Incompatibilities

Will react with water or steam to producetoxic and corrosive fumes.

Long Term Exposure

A study has shown DECC to bemutagenic in two E. coli strains (WP2 and WP2S fromWitkin). However, DECC was not as mutagenic as its closeanalog, dimethylcarbamoyl chloride (DMCC). A suspectedcarcinogen.

Personal Protective Methods

Wear protective gloves andclothing to prevent any reasonable probability of skin contact. Safety equipment suppliers/manufacturers can providerecommendations on the most protective glove/clothingmaterial for your operation. All protective clothing (suits,gloves, footwear, headgear) should be clean, available eachday, and put on before work. Contact lenses should not beworn when working with this chemical. Wear splash-proofchemical goggles and face shield unless full face-piecerespiratory protection is worn. Employees should washimmediately with soap when skin is wet or contaminated.Provide emergency showers and eyewash.

Fire Extinguishing

This chemical is a combustible liquid.Poisonous gases, including nitrogen oxides and chlorides,are produced in fire. Use dry chemical, carbon dioxideextinguishers. Reacts with water, forming corrosive andtoxic fumes. Vapors are heavier than air and will collect inlow areas. Vapors in confined areas may explode whenexposed to fire. Containers may explode in fire. Storagecontainers and parts of containers may rocket great distances, in many directions. If material or contaminated runoff enters waterways, notify downstream users ofpotentially contaminated waters. Notify local health and fireofficials and pollution control agencies. From a secure,explosion-proof location, use water spray to cool exposedcontainers. If cooling streams are ineffective (venting sound increases in volume and pitch, tank discolors, or shows anysigns of deforming), withdraw immediately to a secure position. If employees are expected to fight fires, they must betrained and equipped in OSHA 1910.156. The only respirators recommended for firefighting are self-contained breathing apparatuses that have full face-pieces and are operatedin a pressure-demand or other positive-pressure mode.

Diethylcarbamyl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Diethylcarbamyl chloride Suppliers

Shandong Qianyuan Polymer Material Co. , Ltd.
Tel
18678041314 18765609661
Email
2547772582@qq.com
Country
China
ProdList
877
Advantage
58
Wuhan Beiguofeng Chemical Co.,Ltd.
Tel
027-82886682 18672994909
Email
287621578@qq.com
Country
China
ProdList
124
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from Diethylcarbamyl chloride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Diethylcarbamyl chloride 88-10-8
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-07-14
Hebei Mojin Biotechnology Co., Ltd
Product
Diethylcarbamyl chloride 88-10-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-21
Zhuozhou Wenxi import and Export Co., Ltd
Product
Diethylcarbamyl chloride 88-10-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

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  • 88-10-8
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  • C5H10NOCl
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