Oxytocin acetate
- Product Name
- Oxytocin acetate
- CAS No.
- 6233-83-6
- Chemical Name
- Oxytocin acetate
- Synonyms
- Pitocin Acetate;Synpitan Acetate;Uteracon Acetate;Orasthin Acetate;OXYTOCIN ACETATE;Perlacton Acetate;Syntocinon Acetate;50-56-6 (free base);Oxytocin (O0700000);Oxytocin Monoacetate
- CBNumber
- CB9927175
- Molecular Formula
- C45H70N12O14S2
- Formula Weight
- 1067.25
- MOL File
- 6233-83-6.mol
Oxytocin acetate Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:44.0(Max Conc. mg/mL);41.23(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);46.85(Max Conc. mM) - form
- A crystalline solid
- color
- White to off-white
- Sequence
- Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge:Cys1-Cys6)
- InChIKey
- DSZOEVVLZMNAEH-SIVBSZNNNA-N
Safety
- RIDADR
- UN 2811 6.1 / PGII
- HS Code
- 2937190000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H360May damage fertility or the unborn child
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 1491296
- Product name
- Oxytocin identification
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 15mg
- Price
- $633
- Updated
- 2025/07/31
- Product number
- 11799
- Product name
- Oxytocin (acetate)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $48
- Updated
- 2024/03/01
- Product number
- 11799
- Product name
- Oxytocin (acetate)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $186
- Updated
- 2024/03/01
- Product number
- 11799
- Product name
- Oxytocin (acetate)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $278
- Updated
- 2024/03/01
- Product number
- 11799
- Product name
- Oxytocin (acetate)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $626
- Updated
- 2024/03/01
Oxytocin acetate Chemical Properties,Usage,Production
Description
Oxytocin acetate is an analog of oxytocin, a hormone that stimulates the uterus during labor. It is synthesized by chemically conjugation oxytocin with acetic acid. The stability of this molecule has been proven to be higher than that of oxytocin. This drug demonstrates a stronger binding affinity for the oxytocin receptor, which may be attributed to its increased molecular weight. Additionally, oxytocin acetate has been observed to increase levels of growth factors and fatty acids in tissues when administered intramuscularly, while also stimulating neurotransmission. It exhibits a shorter onset latency and a longer duration of action compared to other analogs. Apart from its medical applications, oxytocin acetate can also serve as a disinfectant in cosmetic use and as an amide-forming agent in organic synthesis reactions.
Chemical Properties
White Solid
Uses
Oxytocin Acetate is the principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland.
Uses
Oxytocin acetate is the salt form of oxytocin and has a more stable structure than oxytocin. Oxytocin is a cyclic nonpeptide that is recommended by the World Health Organization (WHO) for the prevention and treatment of postpartum haemorrhage. Oxytocin is used to therapeutically induce labour and stimulate lactation, and is also the drug of choice for the prevention of postpartum haemorrhage. Oxytocin has also recently been tested for the treatment of social phobia, autism, alcoholism and schizophrenia, and has been investigated for its potential modulatory role in antinociception[1].
Mechanism of action
The actions of oxytocin are mediated by a single G protein-coupled receptor distributed in many peripheral tissues and specific brain areas. Oxytocin secreted into the circulation stimulates uterine contractions during labor and stimulates milk ejection during lactation.
in vivo
During the LMA task, rat core body temperature are modestly decreased. Oxytocin acetate (subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose) produces significantly greater hypothermia (at 0.3 mg/kg) than either saline or the two lower doses of oxytocin. Oxytocin at 0.3 mg/kg produces a significantly greater decrease in temperature than vehicle between 15-60 min post injection, whereas 0.1 mg/kg slightly decreases temperature at the 30 min time point only[1].Oxytocin acetate (0.1 mg/kg) engages in significantly more body sniffing and ano-genital sniffing compared with saline controls. It also increases the total time spent in social interaction (71.6±4.3 s), compared to those receiving vehicle (56.9±4.1 s)[1].
| Animal Model: | Fifty-six male Lister-hooded rats (150–200?g)[1] |
| Dosage: | 0.1?mg/kg-0.3 mg/kg |
| Administration: | Subcutaneous?injection; 0.1?mg/kg-0.3 mg/kg; single dose |
| Result: | Produced significantly greater hypothermia (at 0.3 mg/kg) than the saline group. |
IC 50
Human Endogenous Metabolite
References
[1] MOSTAFA GHASEMISARABBADIEH; Benjamín R S; Sveinbj?rn Gizurarson. The effect of trehalose, antioxidants, and acetate buffer concentration on oxytocin stability[J]. Journal of Peptide Science, 2021. DOI:10.1002/psc.3324.
Oxytocin acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Oxytocin acetate Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
View Lastest Price from Oxytocin acetate manufacturers
- Product
- Oxytocin acetate 6233-83-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1T
- Release date
- 2025-10-02
- Product
- Oxytocin Acetate 6233-83-6
- Price
- US $0.00/box
- Min. Order
- 1box
- Purity
- 0.99
- Supply Ability
- 10tons
- Release date
- 2025-09-26
- Product
- Oxytocin Acetate 6233-83-6
- Price
- US $60.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2025-09-25