Exenatide acetate

Description Background

Product Name: Exenatide acetate
CAS No.: 141732-76-5
Chemical Name: Exenatide acetate
Synonyms: AI315415;Exenatide;AI3 15415;AI3-15415;Extendin-4;Exenatide-d5;Unii-9p1872D4ol;EXENATIDE ACETATE;exendin-4, PC-DAC;Exennatide Acetate
CBNumber: CB4789871
Molecular Formula: C186H286N50O62S
Formula Weight: 4244.60796
MOL File: 141732-76-5.mol

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Exenatide acetate Property

Melting point:: >209°C (dec.)
storage temp.: Refrigerator, under inert atmosphere
solubility: Acetonitrile (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
Sequence: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
CAS DataBase Reference: 141732-76-5(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: E957300
Product name: ExenatideAcetate
Packaging: 5mg
Price: $175
Updated: 2021/12/16

ChemScene

Product number: CS-0106996
Product name: Enfuvirtide(acetate)
Purity: 98.91%
Packaging: 5mg
Price: $72
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FE23212
Product name: Exenatide acetate
Packaging: 10mg
Price: $95
Updated: 2021/12/16

ChemScene

Product number: CS-0106996
Product name: Enfuvirtide(acetate)
Purity: 98.91%
Packaging: 10mg
Price: $108
Updated: 2021/12/16

ChemScene

Product number: CS-0106996
Product name: Enfuvirtide(acetate)
Purity: 98.91%
Packaging: 25mg
Price: $228
Updated: 2021/12/16

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Exenatide acetate Chemical Properties,Usage,Production

Chemical Properties

Exenatide acetate is White Solid

Uses

A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.

Uses

Application of exenatide acetate causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acetate acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide acetate augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide acetate has found use as a medication of diabetes II.

Clinical Use

39-peptide known as an incretin mimetic; an agonist of glucagon-like peptide-1, used adjunctively in type II diabetes mellitus.

Drug interactions

Potentially hazardous interactions with other drugs
Anticoagulants: possibly enhances anticoagulant effect of warfarin.
Other nephrotoxins: avoid concomitant use.

Metabolism

Exenatide is eliminated through the kidneys by glomerular filtration followed by proteolytic degradation.

Description

Exenatide is a single, non-glycosylated, peptide containing 39 amino acids and having a molecular mass of 4186.6 Dalton. Exenatide has the empirical formula C₁₈₄H₂₈₂N₅₀O₆₀S.

Background

Exenatide Derived from the saliva of the gila monster, is a 39 amino acid peptide that mimics the GLP-1 incretin, an insulin secretagogue with glucoregulatory effects. Typical responses to exenatide include improvements in the initial rapid release of endogenous insulin, suppression of glucagon release by the pancreas, regulation of gastric empyting, and reduced appetite - all of which function to lower blood glucose. Exenatide is self-regulating in that it lowers blood sugar when levels are elevated but does not continue to lower blood sugar when levels return to normal, unlike with sulfonylureas or insulins.

Exenatide acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Exenatide acetate Suppliers

Canada 1 China 318 Germany 1 India 4 Israel 1 South Korea 1 Sweden 1 Switzerland 1 United Kingdom 2 United States 13 Global 343

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shaoxing Junyu Biotechnology Co., LTD

Tel: 0571-0571-88211921 19105816207
Email: sales4@gotopbio.com
Country: China
ProdList: 5144
Advantage: 58

Chinese Peptide Company

Tel: 0571-86737118-8680 15988144796
Email: sales@chinesepeptide.com
Country: China
ProdList: 10
Advantage: 58

bociny

Tel: 18939812306
Email: sales@bociny.com
Country: China
ProdList: 207
Advantage: 58

Hubei Zhaoke BIO-CHEMICAL Co., Ltd.

Tel: 18271904430 18271904430
Email: 312523773@qq.com
Country: China
ProdList: 217
Advantage: 58

Shanghai Fine Biotech Co.，Ltd

Tel: 18221172427
Email: sale@fine-biotech.com
Country: China
ProdList: 2772
Advantage: 58

ABRPharm

Tel: 021-52230280 18717909882
Email: fkuebdpe@163.com
Country: China
ProdList: 339
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 15397062932
Email: sales1@gotopbio.com
Country: China
ProdList: 2923
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Hangzhou Zyter Biological & Chemical Technology Co., Ltd.

Tel: 18858184290; 18858184290
Fax: 0086-571-28313105
Email: sales@zyterpharm.com
Country: China
ProdList: 48
Advantage: 49

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View Lastest Price from Exenatide acetate manufacturers

Hainan Fubai Trading Co., LTD

Product: Exenatide acetate 141732-76-5
Price: US $1.00/g
Min. Order: 10g
Purity: 99
Supply Ability: 999
Release date: 2025-09-22

Shanghai Joiny Pharmaceutical Co.,LTD

Product: Exenatide acetate 141732-76-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2025-09-22

Ningbo Qingteng Plastic Cost.,Ltd.

Product: exenatide
Price: US $10.00/box
Min. Order: 1box
Purity: 99%
Supply Ability: 1000Kilogram/Month
Release date: 2025-07-24

141732-76-5, Exenatide acetateRelated Search:

Butyl acetate Sodium acetate Potassium Acetate Glatiramer acetate Exendin-4 Vinyl acetate Octreotide acetate Ethyl acetate Methyl acetate Tocopheryl acetate Pramlintide acetate Icatibant Acetate ACETATE Aluminum acetylacetonate DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) COBALT(II) ACETYLACETONATE Tosylmethyl isocyanide 2,4-PENTANEDIONE, SILVER DERIVATIVE

Exenatide

His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH{2}

EXENATIDE ACETATE(EXENDIN-4)

His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Exenatide Acettate

EXENATIDE ACETATE

ENFUVIRTIDE ACETATE

Extendin-4

Unii-9p1872D4ol

exendin-4, PC-DAC

Exennatide Acetate

Exenatide Acetate salt

Exenatide-d5

Exenatide acetate USP/EP/BP

Type 2 Diabetes Mellitus Exenatide Acetate Stimulate Weight Loss Peptide CAS:?141732-76-5

Exenatide Acetate D5Q: What is Exenatide Acetate D5 Q: What is the CAS Number of Exenatide Acetate D5 Q: What is the storage condition of Exenatide Acetate D5 Q: What are the applications of Exenatide Acetate D5

Exenatide acetateQ: What is Exenatide acetate Q: What is the CAS Number of Exenatide acetate Q: What is the storage condition of Exenatide acetate Q: What are the applications of Exenatide acetate

AI3 15415

AI315415

AI3-15415

Exenatide impurities

Exendin-4|||Extendin-4

Exenatide acetate (acetate)

Exenatide Acetate (GLP1)

(Glu9)-Exenatide (2-39) (Glu9)-Exendin-4 (2-39)

(Des-His1,Glu9)-Exenatide

Exenatide Acetate 1

141732-76-5

41758-74-9

C184H282N50O60SC2H4O2

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141732-76-5