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Exenatide acetate

Product Name
Exenatide acetate
CAS No.
141732-76-5
Chemical Name
Exenatide acetate
Synonyms
AI315415;Exenatide;AI3 15415;AI3-15415;Extendin-4;Exenatide-d5;Unii-9p1872D4ol;EXENATIDE ACETATE;exendin-4, PC-DAC;Exennatide Acetate
CBNumber
CB4789871
Molecular Formula
C186H286N50O62S
Formula Weight
4244.60796
MOL File
141732-76-5.mol
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Exenatide acetate Property

Melting point:
>209°C (dec.)
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Acetonitrile (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Sequence
H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
CAS DataBase Reference
141732-76-5(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E957300
Product name
ExenatideAcetate
Packaging
5mg
Price
$175
Updated
2021/12/16
ChemScene
Product number
CS-0106996
Product name
Enfuvirtide(acetate)
Purity
98.91%
Packaging
25mg
Price
$228
Updated
2021/12/16
Biosynth Carbosynth
Product number
FE23212
Product name
Exenatide acetate
Packaging
50mg
Price
$333
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611418
Product name
Exenatide
Packaging
5mg
Price
$345.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611417
Product name
Exenatide acetate
Packaging
5mg
Price
$345.1
Updated
2021/12/16
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Exenatide acetate Chemical Properties,Usage,Production

Chemical Properties

Exenatide acetate is White Solid

Uses

A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.

Uses

Application of exenatide acetate causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acetate acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide acetate augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide acetate has found use as a medication of diabetes II.

Clinical Use

39-peptide known as an incretin mimetic; an agonist of glucagon-like peptide-1, used adjunctively in type II diabetes mellitus.

Drug interactions

Potentially hazardous interactions with other drugs
Anticoagulants: possibly enhances anticoagulant effect of warfarin.
Other nephrotoxins: avoid concomitant use.

Metabolism

Exenatide is eliminated through the kidneys by glomerular filtration followed by proteolytic degradation.

Exenatide acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Exenatide acetate Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9961
Advantage
55
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-88211921 15572296305
Email
sales4@gotopbio.com
Country
China
ProdList
5144
Advantage
58
Linyi Shengyuan Biotechnology Co., LTD
Tel
18315779352
Email
1904618300@qq.com
Country
China
ProdList
35
Advantage
58
Chinese Peptide Company
Tel
0571-86737118-8680 15988144796
Email
sales@chinesepeptide.com
Country
China
ProdList
12
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.
Tel
18858184290; 18858184290
Fax
0086-571-28313105
Email
sales@zyterpharm.com
Country
China
ProdList
48
Advantage
49
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
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View Lastest Price from Exenatide acetate manufacturers

Wuhan Cell Pharmaceutical Co., Ltd
Product
Exenatide acetate 141732-76-5
Price
US $1.00-9.90/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2023-04-07
Dorne Chemical Technology co. LTD
Product
Exenatide acetate 141732-76-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Exenatide Acetate 141732-76-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-04-16

141732-76-5, Exenatide acetateRelated Search:


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  • EXENATIDE ACETATE(EXENDIN-4)
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  • 141732-76-5