Exenatide acetate
- Product Name
- Exenatide acetate
- CAS No.
- 141732-76-5
- Chemical Name
- Exenatide acetate
- Synonyms
- AI315415;Exenatide;AI3 15415;AI3-15415;Extendin-4;Exenatide-d5;Unii-9p1872D4ol;EXENATIDE ACETATE;exendin-4, PC-DAC;Exennatide Acetate
- CBNumber
- CB4789871
- Molecular Formula
- C186H286N50O62S
- Formula Weight
- 4244.60796
- MOL File
- 141732-76-5.mol
Exenatide acetate Property
- Melting point:
- >209°C (dec.)
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- Acetonitrile (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- Sequence
- H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
- CAS DataBase Reference
- 141732-76-5(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- E957300
- Product name
- ExenatideAcetate
- Packaging
- 5mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- CS-0106996
- Product name
- Enfuvirtide(acetate)
- Purity
- 98.91%
- Packaging
- 25mg
- Price
- $228
- Updated
- 2021/12/16
- Product number
- FE23212
- Product name
- Exenatide acetate
- Packaging
- 50mg
- Price
- $333
- Updated
- 2021/12/16
- Product number
- orb611418
- Product name
- Exenatide
- Packaging
- 5mg
- Price
- $345.1
- Updated
- 2021/12/16
- Product number
- orb611417
- Product name
- Exenatide acetate
- Packaging
- 5mg
- Price
- $345.1
- Updated
- 2021/12/16
Exenatide acetate Chemical Properties,Usage,Production
Chemical Properties
Exenatide acetate is White Solid
Uses
A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.
Uses
Application of exenatide acetate causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acetate acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide acetate augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide acetate has found use as a medication of diabetes II.
Clinical Use
39-peptide known as an incretin mimetic; an agonist of glucagon-like peptide-1, used adjunctively in type II diabetes mellitus.
Drug interactions
Potentially hazardous interactions with other drugs Anticoagulants: possibly enhances anticoagulant effect of warfarin. Other nephrotoxins: avoid concomitant use.
Metabolism
Exenatide is eliminated through the kidneys by glomerular filtration followed by proteolytic degradation.
Exenatide acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Exenatide acetate Suppliers
- Tel
- --
- Fax
- --
- megan.carroll@tevapharm.com
- Country
- Israel
- ProdList
- 296
- Advantage
- 58
View Lastest Price from Exenatide acetate manufacturers
- Product
- Exenatide acetate 141732-76-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2024-03-26
- Product
- Exenatide acetate 141732-76-5
- Price
- US $0.00-0.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 2000
- Release date
- 2024-10-29
- Product
- Exenatide Acetate (GLP1) 141732-76-5
- Price
- US $0.00-0.00/BOX
- Min. Order
- 1BOX
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-11-12