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Exenatide acetate

Product Name
Exenatide acetate
CAS No.
141732-76-5
Chemical Name
Exenatide acetate
Synonyms
AI315415;Exenatide;AI3 15415;AI3-15415;Extendin-4;Exenatide-d5;Unii-9p1872D4ol;EXENATIDE ACETATE;exendin-4, PC-DAC;Exennatide Acetate
CBNumber
CB4789871
Molecular Formula
C186H286N50O62S
Formula Weight
4244.60796
MOL File
141732-76-5.mol
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Exenatide acetate Property

Melting point:
>209°C (dec.)
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Acetonitrile (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Sequence
H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
CAS DataBase Reference
141732-76-5(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E957300
Product name
ExenatideAcetate
Packaging
5mg
Price
$175
Updated
2021/12/16
ChemScene
Product number
CS-0106996
Product name
Enfuvirtide(acetate)
Purity
98.91%
Packaging
25mg
Price
$228
Updated
2021/12/16
Biosynth Carbosynth
Product number
FE23212
Product name
Exenatide acetate
Packaging
50mg
Price
$333
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611418
Product name
Exenatide
Packaging
5mg
Price
$345.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611417
Product name
Exenatide acetate
Packaging
5mg
Price
$345.1
Updated
2021/12/16
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Exenatide acetate Chemical Properties,Usage,Production

Chemical Properties

Exenatide acetate is White Solid

Uses

A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.

Uses

Application of exenatide acetate causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acetate acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide acetate augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide acetate has found use as a medication of diabetes II.

Clinical Use

39-peptide known as an incretin mimetic; an agonist of glucagon-like peptide-1, used adjunctively in type II diabetes mellitus.

Drug interactions

Potentially hazardous interactions with other drugs
Anticoagulants: possibly enhances anticoagulant effect of warfarin.
Other nephrotoxins: avoid concomitant use.

Metabolism

Exenatide is eliminated through the kidneys by glomerular filtration followed by proteolytic degradation.

Exenatide acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Exenatide acetate Suppliers

Canada 1 China 282 Germany 1 India 4 Israel 1 South Korea 1 Sweden 1 Switzerland 1 United Kingdom 2 United States 14 Global 308
GL Biochem (Shanghai) Ltd
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View Lastest Price from Exenatide acetate manufacturers

Dorne Chemical Technology co. LTD
Product
Exenatide acetate 141732-76-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
Shandong Huizhihan Supply Chain Co., Ltd
Product
Exenatide acetate 141732-76-5
Price
US $0.00-0.00/box
Min. Order
1box
Purity
99%
Supply Ability
2000
Release date
2024-10-29
Shandong Huizhihan Supply Chain Co., Ltd
Product
Exenatide Acetate (GLP1) 141732-76-5
Price
US $0.00-0.00/BOX
Min. Order
1BOX
Purity
99%
Supply Ability
20T
Release date
2024-11-12

141732-76-5, Exenatide acetateRelated Search:

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