2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
Description References- Product Name
- 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
- CAS No.
- 50508-60-6
- Chemical Name
- 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
- Synonyms
- 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene;2-Amino-5-ethyl-3-(2-chlorobenzoyl)thiophene;Methanone,(2-aMino-5-ethyl-3-thienyl)(2-chlorophenyl)-;(2-AMino-5-ethylthiophen-3-yl)(2-chlorophenyl)Methanone
- CBNumber
- CB9947146
- Molecular Formula
- C13H12ClNOS
- Formula Weight
- 265.76
- MOL File
- 50508-60-6.mol
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Property
- Boiling point:
- 454.8±45.0 °C(Predicted)
- Density
- 1.302
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): insol
- form
- a crystalline solid
- pka
- -1.81±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A603355
- Product name
- 2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- HCH0011027
- Product name
- 2-AMINO-3-O-CHLOROBENZOYL-5-ETHYLTHIOPHENE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.2
- Updated
- 2021/12/16
- Product number
- Z5530
- Product name
- 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- 093974
- Product name
- (2-Amino-5-ethylthiophen-3-yl)-(2-chlorophenyl)methanone
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $756
- Updated
- 2021/12/16
- Product number
- 093974
- Product name
- (2-Amino-5-ethylthiophen-3-yl)-(2-chlorophenyl)methanone
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1647
- Updated
- 2021/12/16
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Chemical Properties,Usage,Production
Description
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene can be used as the raw material for the synthesis of Etizolam, which is an important sedative hypnotic and antidepressant drug. Its derivative, 2-amino-3-(p-chlorobenzoyl) thiophene scaffold has been widely employed as a pharmacophore for the identification of small molecules acting as allosteric modulators at the adenosine A1 receptor.
References
Kai, Yong Mao, et al. "An Improved Synthesis of Etizolam." Journal of Southwest University of Science & Technology (2014).
Romagnoli, R, et al. Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study..Longing for the end. Macmillan, 2015:185–204.
Chemical Properties
Yellow Solid
Uses
Used in the preparation of thienylamide derivatives as cholecystokinin inhibitors.
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Suppliers
View Lastest Price from 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene manufacturers
- Product
- 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene 50508-60-6
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-22