2-Amino-3-o-chlorobenzoyl-5-ethylthiophene

ChemicalBook > CAS DataBase List > 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene

Description References

Product Name: 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
CAS No.: 50508-60-6
Chemical Name: 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
Synonyms: 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene;2-Amino-5-ethyl-3-(2-chlorobenzoyl)thiophene;Methanone,(2-aMino-5-ethyl-3-thienyl)(2-chlorophenyl)-;(2-AMino-5-ethylthiophen-3-yl)(2-chlorophenyl)Methanone
CBNumber: CB9947146
Molecular Formula: C13H12ClNOS
Formula Weight: 265.76
MOL File: 50508-60-6.mol

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2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Property

Boiling point:: 454.8±45.0 °C(Predicted)
Density: 1.302
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): insol
form: a crystalline solid
pka: -1.81±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A603355
Product name: 2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene
Packaging: 100mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: Z5530
Product name: 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
Packaging: 1g
Price: $120
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0011027
Product name: 2-AMINO-3-O-CHLOROBENZOYL-5-ETHYLTHIOPHENE
Purity: 95.00%
Packaging: 5MG
Price: $500.2
Updated: 2021/12/16

Matrix Scientific

Product number: 093974
Product name: (2-Amino-5-ethylthiophen-3-yl)-(2-chlorophenyl)methanone
Purity: 95+%
Packaging: 250mg
Price: $756
Updated: 2021/12/16

Matrix Scientific

Product number: 093974
Product name: (2-Amino-5-ethylthiophen-3-yl)-(2-chlorophenyl)methanone
Purity: 95+%
Packaging: 1g
Price: $1647
Updated: 2021/12/16

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2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Chemical Properties,Usage,Production

Description

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene can be used as the raw material for the synthesis of Etizolam, which is an important sedative hypnotic and antidepressant drug. Its derivative, 2-amino-3-(p-chlorobenzoyl) thiophene scaffold has been widely employed as a pharmacophore for the identification of small molecules acting as allosteric modulators at the adenosine A1 receptor.

References

Kai, Yong Mao, et al. "An Improved Synthesis of Etizolam." Journal of Southwest University of Science & Technology (2014).
Romagnoli, R, et al. Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study..Longing for the end. Macmillan, 2015:185–204.

Chemical Properties

Yellow Solid

Uses

Used in the preparation of thienylamide derivatives as cholecystokinin inhibitors.

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene manufacturers

Career Henan Chemical Co

Product: 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene 50508-60-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-22

50508-60-6, 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Related Search:

Etizolam JP Luminol P-AMINOBENZAMIDE GLUTAMIC ACID Benzoyl chloride, 4-amino- (9CI) Anthranilamide AKOS 221-03 AKOS 221-04 BENZO[B]THIOPHENE-6-CARBOXYLIC ACID, 2-AMINO-3-(2-CHLOROBENZOYL)-4,5,6,7-TETRAHYDRO-, ETHYL ESTER AKOS 92301 BENZO[B]THIOPHENE-6-CARBOXYLIC ACID, 2-AMINO-3-(2-CHLOROBENZOYL)-4,5,6,7-TETRAHYDRO-, METHYL ESTER 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene

2-Amino-5-ethyl-3-(2-chlorobenzoyl)thiophene

Methanone,(2-aMino-5-ethyl-3-thienyl)(2-chlorophenyl)-

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50508-60-6

Thiophene heterocycles