CPNQ
- Product Name
- CPNQ
- CAS No.
- 115687-05-3
- Chemical Name
- CPNQ
- Synonyms
- B2;CPNQ;SIRT2-IN-8;SIRT2 Inhibitor, B2;Linazolamide intermediate B impurity 2;5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline;(4-chlorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone;Methanone, (4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]-;Sirtuin,Parkinson’s diseases,Huntington’s diseases,Inhibitor,B2,inhibit,B-2
- CBNumber
- CB9972382
- Molecular Formula
- C20H17ClN4O3
- Formula Weight
- 396.83
- MOL File
- 115687-05-3.mol
CPNQ Property
- Melting point:
- 174-176°C
- Boiling point:
- 645.5±55.0 °C(Predicted)
- Density
- 1.412±0.06 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- H2O: insoluble <2mg/mL
- pka
- 2.30±0.29(Predicted)
- form
- solid
- color
- brown
Safety
- Hazard Codes
- T
- Risk Statements
- 25-36/37/38
- Safety Statements
- 26-45
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C3118
- Product name
- CPNQ
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- C3118
- Product name
- CPNQ
- Purity
- ≥98% (HPLC), solid
- Packaging
- 25mg
- Price
- $719
- Updated
- 2021/12/16
- Product number
- B820015
- Product name
- B2
- Packaging
- 1mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 254701
- Product name
- B2
- Packaging
- 10mg
- Price
- $403
- Updated
- 2021/12/16
- Product number
- API0008461
- Product name
- CPNQ
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $673.08
- Updated
- 2021/12/16
CPNQ Chemical Properties,Usage,Production
Uses
B2 is a cell permeable inhibitor of SIRT2 (sirtuin 2). Multidrug resistance protein 4 (MRP4) inhibitor in tumors such as neuroblastoma and colorectal cancer.
Definition
ChEBI: (4-chlorophenyl)-[4-(8-nitro-5-quinolinyl)-1-piperazinyl]methanone is a N-arylpiperazine.
Biological Activity
Promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease. Prevents huntingtin-mediated proteasome dysfunction and reduces α -synuclein-mediated toxicity.
CPNQ Preparation Products And Raw materials
Raw materials
Preparation Products
CPNQ Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77