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Quinoline compounds

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Quinoline and isoquinoline are two isomers of benzo pyridine, both present in coal tar. The quinoline and isoquinoline and their many substituted derivatives, all can get from cyclizing benzene derivatives by the ring system. The basic reaction of synthesizing quinoline ring compound is that get aniline, glycerol, sulfuric acid and oxidizing agent (nitrobenzene, etc.) heated together. Since glycerol is dehydrated to become acrolein and then react with aniline, various aniline derivatives and other α, β- unsaturated carbonyl compounds can be used to synthesize quinoline compounds which has a substituent on a ring. Such as 4-methyl-quinoline (Le Puy-pyridine) is obtained from aniline and methyl - vinyl ketone . The way to synthesize Other quinoline compounds synthesis including the condensation of anthranilic ketone formaldehyde condensation. Such as 2-methyl-quinoline (QUINALDINIC) is prepared by the condensation of o-benzaldehyde and acetone.

Quinoline compound refers quinoline and its homologue, a bicyclic aromatics with nitrogen(hetero). Quinoline compounds are known as the heavy pyridine which is called tar base together with pyridine bases, a basic product obtained from high-temperature coal tar processing, including quinoline,isoquinoline, quinoline methyl and dimethyl quinoline and so on. Quinoline compounds mainly exist in the coal tar naphthalene oil fraction and wash oil fraction.The content of quinoline compounds in coal tar is about 0.3% to 0.5%. Quinoline compounds have a special smell, when they are exposed to air or sunlight the color becomes deeper gradually.

Quinoline compounds can be used to produce medicine, dyes, photographic materials, rubber, solvents and chemical reagents. Quinoline medicine is primarily used in the manufacture of niacin-based, 8-hydroxy quinoline and quinine-based drugs. Niacin-based drugs including nicotinamide, tonic, stimulant and treatment of tapeworm medicine; 8-hydroxy quinoline can be used to make the treatment of amoebic coccidiosis medicine, trauma disinfectants, mildew and textile auxiliaries and the like. Primaquine Ning, quinine chloride and hydroxylamine quinine is a synthetic treatment of malaria medicine. Isoquinoline can be used in the manufacture of pesticides, antimalarials, rubber vulcanization accelerator and determination of rare metals by chemical agents. Methyl-quinoline can be used for the manufacture of color film sensitizing agent and dye, also used as a solvent, impregnating agents, corrosion inhibitors, quinine-based drugs and pesticides. The extraction of quinoline compounds is same as the heavy pyridine refined.

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Structure:
Chemical Name:
2,8-DICHLOROQUINOLINE
CAS:
4470-83-1
MF:
C9H5Cl2N
Structure:
Chemical Name:
4-METHOXY-2-QUINOLINECARBOXYLIC ACID
CAS:
15733-83-2
MF:
C11H9NO3
Structure:
Chemical Name:
4-Amino-6-bromoquinoline
CAS:
65340-73-0
MF:
C9H7BrN2
Structure:
Chemical Name:
1,3-Dichloro-7-methylisoquinoline
CAS:
21902-37-4
MF:
C10H7Cl2N
Structure:
Chemical Name:
5-Amino-1-chloroisoquinoline
CAS:
374554-54-8
MF:
C9H7ClN2
Structure:
Chemical Name:
QUINOLINE-6-CARBOXYLIC ACID ETHYL ESTER
CAS:
73987-38-9
MF:
C12H11NO2
Structure:
Chemical Name:
5,7-difluoroquinoline
CAS:
34522-72-0
MF:
C9H5F2N
Structure:
Chemical Name:
4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
CAS:
13721-01-2
MF:
C10H7NO3
Structure:
Chemical Name:
6-chloroquinoline-8-carboxylic acid
CAS:
6456-78-6
MF:
C10H6ClNO2
Structure:
Chemical Name:
2,2'-BI-4-LEPIDINE
CAS:
7654-51-5
MF:
C20H16N2
Structure:
Chemical Name:
8-HYDROXYQUINOLINE-2-CARBONITRILE
CAS:
6759-78-0
MF:
C10H6N2O
Structure:
Chemical Name:
TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE
CAS:
258515-65-0
MF:
C14H18BrNO2
Structure:
Chemical Name:
6-CHLORO-2-HYDROXYQUINOLINE
CAS:
1810-67-9
MF:
C9H6ClNO
Structure:
Chemical Name:
3-Chloroquinoline
CAS:
612-59-9
MF:
C9H6ClN
Structure:
Chemical Name:
QUINALDIC ACID SODIUM SALT
CAS:
16907-79-2
MF:
C10H8NNaO2
Structure:
Chemical Name:
8-Bromoacetylquinoline hydrobromide
CAS:
859962-48-4
MF:
C11H9Br2NO
Structure:
Chemical Name:
8-Fluoroisoquinoline
CAS:
1075-00-9
MF:
C9H6FN
Structure:
Chemical Name:
6-METHOXYQUINOLINE N-OXIDE
CAS:
6563-13-9
MF:
C10H9NO2
Structure:
Chemical Name:
LEPIDINE ISOAMYL IODIDE
CAS:
94319-01-4
MF:
C15H20IN
Structure:
Chemical Name:
5-Chloro-3H-quinazolin-4-one
CAS:
60233-66-1
MF:
C8H5ClN2O
Structure:
Chemical Name:
2,7-DIMETHYLQUINOLINE
CAS:
93-37-8
MF:
C11H11N
Structure:
Chemical Name:
6,8-DIMETHOXY-4-METHYLQUINOLINE
CAS:
51049-14-0
MF:
C12H13NO2
Structure:
Chemical Name:
4-HYDROXY-6-METHYLQUINAZOLINE
CAS:
19181-53-4
MF:
C9H8N2O
Structure:
Chemical Name:
N-BENZYLQUINIDINIUM CHLORIDE
CAS:
77481-82-4
MF:
C27H31ClN2O2
Structure:
Chemical Name:
ETHYL 8-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLATE
CAS:
35975-57-6
MF:
C12H10BrNO3
Structure:
Chemical Name:
6-Chloroquinazoline-2,4(1H,3H)-dione
CAS:
1640-60-4
MF:
C8H5ClN2O2
Structure:
Chemical Name:
8-Quinolinamine,5,6,7,8-tetrahydro-,(8S)-(9CI)
CAS:
369656-57-5
MF:
C9H12N2
Structure:
Chemical Name:
1-METHYL-1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID
CAS:
162648-46-6
MF:
C11H13NO2
Structure:
Chemical Name:
6-CHLORO-5-NITROQUINOLINE
CAS:
86984-32-9
MF:
C9H5ClN2O2
Structure:
Chemical Name:
QUINOLINE SULPHATE
CAS:
54957-90-3
MF:
C9H9NO4S
Structure:
Chemical Name:
6-Bromo-7-fluoroquinoline
CAS:
127827-52-5
MF:
C9H5BrFN
Structure:
Chemical Name:
4-Amino-3-bromoquinoline
CAS:
36825-36-2
MF:
C9H7BrN2
Structure:
Chemical Name:
6-TERT-BUTYLQUINOLINE
CAS:
68141-13-9
MF:
C13H15N
Structure:
Chemical Name:
5-METHOXYQUINOLINE
CAS:
6931-19-7
MF:
C10H9NO
Structure:
Chemical Name:
6-CHLOROQUINOXALINE
CAS:
5448-43-1
MF:
C8H5ClN2
Structure:
Chemical Name:
4-CHLORO-7-(3-CHLORO-PROPOXY)-6-METHOXY-QUINOLINE-3-CARBONITRILE
CAS:
214470-68-5
MF:
C14H12Cl2N2O2
Structure:
Chemical Name:
6-Bromo-4-methylquinoline
CAS:
41037-28-9
MF:
C10H8BrN
Structure:
Chemical Name:
QUINOLINIUM DICHROMATE
CAS:
56549-24-7
MF:
C18H16Cr2N2O7
Structure:
Chemical Name:
ETHYL 4-HYDROXY-2-QUINOLINECARBOXYLATE
CAS:
24782-43-2
MF:
C12H11NO3
Structure:
Chemical Name:
6-HYDROXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID
CAS:
76824-99-2
MF:
C10H11NO3
Structure:
Chemical Name:
QUINIDINE HYDROCHLORIDE
CAS:
6151-40-2
MF:
C20H27ClN2O3
Structure:
Chemical Name:
3-Methoxyquinoline
CAS:
6931-17-5
MF:
C10H9NO
Structure:
Chemical Name:
8-METHOXYQUINOLINE
CAS:
938-33-0
MF:
C10H9NO
Structure:
Chemical Name:
5,7-Difluoro-6-bromoquinoline
CAS:
1022091-49-1
MF:
C9H4BrF2N
Structure:
Chemical Name:
7-Benzyloxy-4-chloro-6-methoxy-quinoline
CAS:
286371-49-1
MF:
C17H14ClNO2
Structure:
Chemical Name:
8-CHLORO-2-HYDROXYQUINOLINE
CAS:
23981-25-1
MF:
C9H6ClNO
Structure:
Chemical Name:
1-Ethyl-7-nitro-1,2,3,4-tetrahydroquinoline
CAS:
57883-28-0
MF:
C11H14N2O2
Structure:
Chemical Name:
2-QUINOLINETHIOL
CAS:
2637-37-8
MF:
C9H7NS
Structure:
Chemical Name:
OXINE-COPPER
CAS:
13014-03-4
MF:
C18H12CuN2O2
Structure:
Chemical Name:
4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
CAS:
27568-04-3
MF:
C13H13NO4
Structure:
Chemical Name:
ETHYL 4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE
CAS:
391-02-6
MF:
C13H10F3NO3
Structure:
Chemical Name:
8-Hydroxyquinoline sulfate monohydrate
CAS:
207386-91-2
MF:
C9H11NO6S
Structure:
Chemical Name:
7-TRIFLUOROMETHYL-4-QUINOLINETHIOL
CAS:
64415-07-2
MF:
C10H6F3NS
Structure:
Chemical Name:
5-Methylquinoline
CAS:
7661-55-4
MF:
C10H9N
Structure:
Chemical Name:
2-Methoxyquinoline-3-boronic acid
CAS:
886853-93-6
MF:
C10H10BNO3
Structure:
Chemical Name:
8-Bromo-7-methoxyquinoline
CAS:
36023-06-0
MF:
C10H8BrNO
Structure:
Chemical Name:
7-methoxy-4-methylquinoline
CAS:
6238-12-6
MF:
C11H11NO
Structure:
Chemical Name:
4-HYDROXY-2-METHYLQUINOLINE-6-CARBOXYLIC ACID ETHYL ESTER
CAS:
300590-94-7
MF:
C13H13NO3
Structure:
Chemical Name:
3-QUINOLINEBORONIC ACID HYDROCHLORIDE
CAS:
850568-71-7
MF:
C9H9BClNO2
Structure:
Chemical Name:
8-HYDROXYQUINOLINE-5-SULFONIC ACID
CAS:
207386-92-3
MF:
C9H7NO4S
Structure:
Chemical Name:
7-Chloro-4-iodoquinoline
CAS:
98591-57-2
MF:
C9H5ClIN
Structure:
Chemical Name:
4-CHLORO-7-HYDROXY-6-METHOXY-QUINOLINE-3-CARBONITRILE
CAS:
263149-10-6
MF:
C11H7ClN2O2
Structure:
Chemical Name:
Ethyl 7-chloro-4-hydroxy-8-methylquinoline-3-carboxylate
CAS:
5350-94-7
MF:
C13H12ClNO3
Structure:
Chemical Name:
8-Amino-4-methylquinoline
CAS:
62748-01-0
MF:
C10H10N2
Structure:
Chemical Name:
4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-QUINOLINE
CAS:
1035458-54-8
MF:
C15H18BNO2
Structure:
Chemical Name:
2-PHENYL-QUINOLINE-4-CARBOXYLIC ACID METHYL ESTER
CAS:
4546-48-9
MF:
C17H13NO2
Structure:
Chemical Name:
3,4,5,6,7,8-HEXAHYDRO-2(1H)-QUINOLINONE
CAS:
10333-11-6
MF:
C9H13NO
Structure:
Chemical Name:
ethyl2-methylquinoline-6-carboxylate
CAS:
855763-77-8
MF:
C13H13NO2
Structure:
Chemical Name:
Indolo[3,2-b]carbazole
CAS:
6336-32-9
MF:
C18H12N2
Structure:
Chemical Name:
Ethyl 6,8-difluoro-4-hydroxyquinoline-3-carboxylate
CAS:
107555-38-4
MF:
C12H9F2NO3
Structure:
Chemical Name:
QUINOLINE-3-CARBOXYLIC ACID
CAS:
118803-81-9
MF:
C10H7NO2
Structure:
Chemical Name:
2-METHYL-QUINOLINE-4-CARBOXYLIC ACID
CAS:
634-38-8
MF:
C11H9NO2
Structure:
Chemical Name:
6-(TRIFLUOROMETHYL)QUINOLINE,95% MIN(HPLC)
CAS:
325-13-3
MF:
C10H6F3N
Structure:
Chemical Name:
8-Bromo-7-quinolinol
CAS:
90224-71-8
MF:
C9H6BrNO
Structure:
Chemical Name:
3-BROMOQUINOLIN-5-OL
CAS:
1123738-15-7
MF:
C9H6BrNO
Structure:
Chemical Name:
4-AMINO-3-NITROQUINOLINE
CAS:
42606-33-7
MF:
C9H7N3O2
Structure:
Chemical Name:
QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
CAS:
50741-46-3
MF:
C12H11NO2
Structure:
Chemical Name:
[99010-09-0], C13H17N3,215.30
CAS:
935521-01-0
MF:
C13H18ClN3
Structure:
Chemical Name:
3-BROMO-6-METHOXYQUINOLINE
CAS:
14036-96-5
MF:
C10H8BrNO
Structure:
Chemical Name:
ETHYL 2-(QUINOLIN-6-YL)ACETATE
CAS:
5622-38-8
MF:
C13H13NO2
Structure:
Chemical Name:
4-HYDROXYQUINOLINE
CAS:
529-37-3
MF:
C9H7NO
Structure:
Chemical Name:
8,8'-DIQUINOLYL DISULFIDE
CAS:
1160-28-7
MF:
C18H12N2S2
Structure:
Chemical Name:
7,8-Dichloroisoquinoline
CAS:
61563-36-8
MF:
C9H5Cl2N
Structure:
Chemical Name:
ethyl4-amino-2-methylquinoline-6-carboxylate
CAS:
100795-25-3
MF:
C13H14N2O2
Structure:
Chemical Name:
8-Chloro-2-methylquinazolin-4(3H)-one
CAS:
19407-54-6
MF:
C9H7ClN2O
Structure:
Chemical Name:
2(1H)-Quinolinone, 1,4-dimethyl-
CAS:
2584-47-6
MF:
C11H11NO
Structure:
Chemical Name:
4-(8-HYDROXY-5-QUINOLYLAZO)-1-NAPHTHALENESULFONIC ACID DISODIUM SALT
MF:
C19H13N3Na2O4S+2
Structure:
Chemical Name:
6-AMINOQUINOLINE HYDROCHLORIDE
CAS:
53472-17-6
MF:
C9H9ClN2
Structure:
Chemical Name:
1,3-Dichloro-7-fluoroisoquinoline
CAS:
941294-25-3
MF:
C9H4Cl2FN
Structure:
Chemical Name:
8-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
CAS:
35973-17-2
MF:
C10H6BrNO3
Structure:
Chemical Name:
2-CHLORO-3-CYANOQUINOLINE
CAS:
95104-21-5
MF:
C10H5ClN2
Structure:
Chemical Name:
6-Bromo-4-methoxyquinoline
CAS:
874792-20-8
MF:
C10H8BrNO
Structure:
Chemical Name:
6,7-Dichloro-3-(trifluoromethyl)quinoxalin-2(1H)-one
CAS:
477857-25-3
MF:
C9H3Cl2F3N2O
Structure:
Chemical Name:
6(5H)-quinolinone,7,8-dihydro-
CAS:
27463-91-8
MF:
C9H9NO
Structure:
Chemical Name:
8-HYDROXYQUINOLINE-2-SULFONIC ACID MONOHYDRATE
CAS:
20946-17-2
MF:
C9H7NO4S
Structure:
Chemical Name:
N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine
CAS:
281211-09-4
MF:
C12H12Cl3N3
Structure:
Chemical Name:
6,7-Dichloroquinoline
CAS:
40635-11-8
MF:
C9H5Cl2N
Structure:
Chemical Name:
8-METHYL-4-QUINAZOLONE
CAS:
19181-54-5
MF:
C9H8N2O
Structure:
Chemical Name:
2-METHYL-1,5-NAPHTHYRIDINE
CAS:
7675-32-3
MF:
C9H8N2
Structure:
Chemical Name:
8-Quinolinamine,5,6,7,8-tetrahydro-,(8R)-(9CI)
CAS:
369655-84-5
MF:
C9H12N2