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Contraceptives

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The reproductive process is a complex physiological process including sperm and egg formation and maturation, ovulation, fertilization, implantation and embryonic development and many other steps. Blocking any of the above steps can achieve the purpose of contraception and termination of pregnancy.

The male drugs for birth control; there are few such kinds of drugs. In our country, only gossypol has been subject to mature study. Gossypol is a yellow phenolic substance extracted from the roots, stems and seeds of cotton. Administration of this drug can reduce the number of sperm, even to zero sperm with the prolonged treatment time. With the trials of more than 4000 healthy men, the effective rate is 99% or more.

Contraceptive drugs of female; According to the difference action steps, it can be divided into:
(1) contraceptive drugs inhibition of ovulation; this is a major category of female contraceptive drugs, consisting of different types of estrogen and progesterone in different doses.There are short-acting oral contraceptives. Commonly used compounds include norethisterone tablets, compound megestrol acetate tablets and long-term injection contraceptives such as compound hydroxyprogesterone caproate. Adverse reactions of these drugs include the emergence of early pregnancy response, uterine irregular bleeding, amenorrhea, decreased breast milk, coagulation hyperthyroidism and so on. It is not applicable to women of acute and chronic liver disease, diabetes and uterine fibroids.
(2) Anti-implantation contraceptives. Such drugs can interfere with the normal development of the endometrium so that it is not conducive to pregnancy implantation. China mostly applies large doses of norethisterone or megestrol acetate. The advantage of this class of drugs is not subject to restrictions on the application of the menstrual cycle.
(3) Contraceptives mainly affect the uterine and placental function: such drugs are still under research and have not yet used in large-scale. The main drug is prostaglandin.

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Structure:
Chemical Name:
Ulipristal Acetate
CAS:
126784-99-4
MF:
C30H37NO4
Structure:
Chemical Name:
Poly(vinyl alcohol)
CAS:
9002-89-5
MF:
C2H4O
Structure:
Chemical Name:
Levonorgestrel
CAS:
797-63-7
MF:
C21H28O2
Structure:
Chemical Name:
Megestrol acetate
CAS:
595-33-5
MF:
C24H32O4
Structure:
Chemical Name:
Hydroxyprogesterone caproate
CAS:
630-56-8
MF:
C27H40O4
Structure:
Chemical Name:
Etonogestrel
CAS:
54048-10-1
MF:
C22H28O2
Structure:
Chemical Name:
(-)-Gossypol
CAS:
90141-22-3
MF:
C30H30O8
Structure:
Chemical Name:
PHENYLMERCURIC ACETATE
CAS:
62-38-4
MF:
C8H8HgO2
Structure:
Chemical Name:
Trenbolone
CAS:
10161-33-8
MF:
C18H22O2
Structure:
Chemical Name:
17α-Hydroxyprogesterone
CAS:
68-96-2
MF:
C21H30O3
Structure:
Chemical Name:
POLYETHYLENE GLYCOL MONO-4-NONYLPHENYL ETHER
CAS:
26027-38-3
MF:
C17H35O4S.Na
Structure:
Chemical Name:
Norethindrone
CAS:
68-22-4
MF:
C20H26O2
Structure:
Chemical Name:
Nonylphenoxypoly(ethyleneoxy)ethanol
CAS:
9016-45-9
MF:
C19H32O3
Structure:
Chemical Name:
Desogestrel
CAS:
54024-22-5
MF:
C22H30O
Structure:
Chemical Name:
Norgestrel
CAS:
6533-00-2
MF:
C21H28O2
Structure:
Chemical Name:
GOSSYPOL
CAS:
303-45-7
MF:
C30H30O8
Structure:
Chemical Name:
Megestrol
CAS:
3562-63-8
MF:
C22H30O3
Structure:
Chemical Name:
Gossypol-acetic acid
CAS:
12542-36-8
MF:
C32H34O10
Chemical Name:
VINOL 523
CAS:
98002-49-4
MF:
[-CH2-CHOH-]n
Structure:
Chemical Name:
CHLORMADINON
CAS:
1961-77-9
MF:
C21H27ClO3
Structure:
Chemical Name:
Poly(vinyl alcohol)
CAS:
25213-24-5
MF:
C6H10O3
Structure:
Chemical Name:
NONOXYNOL 9
CAS:
14409-72-4
MF:
C33H60O10
Structure:
Chemical Name:
Quingestanol
CAS:
10592-65-1
MF:
C25H34O2
Structure:
Chemical Name:
Norgestimate
CAS:
35189-28-7
MF:
C23H31NO3
Structure:
Chemical Name:
Gestrinone
CAS:
16320-04-0
MF:
C21H24O2
Structure:
Chemical Name:
Ethynodiol diacetate
CAS:
297-76-7
MF:
C24H32O4
Structure:
Chemical Name:
Hydroxyprogesterone acetate
CAS:
302-23-8
MF:
C23H32O4
Structure:
Chemical Name:
Quingestrone
CAS:
67-95-8
MF:
C26H38O2
Structure:
Chemical Name:
NORETHYNODREL
CAS:
68-23-5
MF:
C20H26O2
Structure:
Chemical Name:
Tibolone
CAS:
5630-53-5
MF:
C21H28O2
Structure:
Chemical Name:
Chlormadinone acetate
CAS:
302-22-7
MF:
C23H29ClO4