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Sulfonamides and synergist

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Sulfa drugs developed rapidly in the 1930s, and there had been more than 20 species of the drugs for the clinical application. the status of sulfa drugs in chemotherapeutic agents declined after 1940s due to the occurrence of penicillin and other antibiotics. But sulfa drugs, whose  antibacterial activity will be enhanced when combined with trimethoprim the antibacterial synergist, are still commonly used antibacterial drugs for the advantages of broad antibacterial spectrum, enabled to be administered orally, more rapid absorption. Clarifying the mechanism of the action of sulfa drugs established anti-metabolic theory and opened up a new way for the development of new drugs. Currently there are sulfadiazine and sulfamethoxazole that are used most widely in clinical.

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Structure:
Chemical Name:
4-(5-BROMO-2-METHOXYBENZENESULPHONYL)MORPHOLINE
CAS:
325809-68-5
MF:
C11H14BrNO4S
Structure:
Chemical Name:
5-(N,N-DIMETHYLSULFAMOYL)-2-METHYLPHENYLBORONIC ACID
CAS:
871332-99-9
MF:
C9H14BNO4S
Structure:
Chemical Name:
4-BROMO-N-TERT-BUTYL-BENZENESULFONAMIDE
CAS:
93281-65-3
MF:
C10H14BrNO2S
Structure:
Chemical Name:
4-Bromo-N-isopropylbenzenesulfonamide
CAS:
1984-27-6
MF:
C9H12BrNO2S
Structure:
Chemical Name:
2-METHYL-5-(PIPERIDIN-1-YLSULFONYL)PHENYLBORONIC ACID
CAS:
871333-00-5
MF:
C12H18BNO4S
Structure:
Chemical Name:
1-(5-BROMO-2-METHOXYBENZENESULPHONYL)PIPERIDINE
CAS:
295360-83-7
MF:
C12H16BrNO3S
Structure:
Chemical Name:
2-Bromo-N,N-diethylbenzenesulphonamide
CAS:
65000-12-6
MF:
C10H14BrNO2S
Structure:
Chemical Name:
4-[(2-Bromophenyl)sulphonyl]morpholine
CAS:
688798-57-4
MF:
C10H12BrNO3S
Structure:
Chemical Name:
4-Methoxyphenyl mesylate, 4-[(Methylsulphonyl)oxy]anisole
CAS:
19013-30-0
MF:
C8H10O4S
Structure:
Chemical Name:
5-BROMO-N,N-DIMETHYL-2-METHOXYBENZENESULFONAMIDE
CAS:
871269-16-8
MF:
C9H12BrNO3S
Structure:
Chemical Name:
3-(TERT-BUTYLAMINOSULPHONYL)BENZENEBORONIC ACID
CAS:
221290-14-8
MF:
C10H16BNO4S
Structure:
Chemical Name:
3-(3-BROMOPHENYLSULPHONAMIDO)BENZENEBORONIC ACID 95
CAS:
913835-31-1
MF:
C12H11BBrNO4S
Structure:
Chemical Name:
3-(4-SULFAMOYL-PHENYL)-PROPIONIC ACID
CAS:
90610-69-8
MF:
C9H11NO4S
Structure:
Chemical Name:
4-(N-CYCLOHEXYLSULPHONAMIDO)BENZENEBORONIC ACID
CAS:
871329-66-7
MF:
C12H18BNO4S
Structure:
Chemical Name:
4-(1-PIPERIDINYLSULFONYL)PHENYLBORONIC ACID
CAS:
486422-58-6
MF:
C11H16BNO4S
Structure:
Chemical Name:
4-(N-THIOMORPHOLINYLSULFONYL)PHENYLBORONIC ACID
CAS:
871329-69-0
MF:
C10H14BNO4S2
Structure:
Chemical Name:
3-Bromo-N-propylbenzamide
CAS:
35306-74-2
MF:
C10H12BrNO
Structure:
Chemical Name:
N-BUTYL 3-NITROBENZENESULFONAMIDE
CAS:
89840-72-2
MF:
C10H14N2O4S
Structure:
Chemical Name:
4-(4-MORPHOLINYLSULFONYL)PHENYLBORONIC ACID
CAS:
486422-69-9
MF:
C14H24BN3O4S
Structure:
Chemical Name:
3-(N,N-DIETHYLSULPHONAMIDO)BENZENEBORONIC ACID
CAS:
871329-58-7
MF:
C10H16BNO4S
Structure:
Chemical Name:
Sulfisoxazole
CAS:
127-69-5
MF:
C11H13N3O3S
Structure:
Chemical Name:
Sulfaquinoxaline
CAS:
59-40-5
MF:
C14H12N4O2S
Structure:
Chemical Name:
5-BROMO-2-METHOXY-N-METHYLBENZENESULFONAMIDE
CAS:
871269-17-9
MF:
C8H10BrNO3S
Structure:
Chemical Name:
N-METHYL 3-NITROBENZENESULFONAMIDE
CAS:
58955-78-5
MF:
C7H8N2O4S
Structure:
Chemical Name:
1-(3-BROMOPHENYLSULFONYL)PIPERIDINE
CAS:
871269-12-4
MF:
C11H14BrNO2S
Structure:
Chemical Name:
4-(Pyridin-3-ylsulphonyl)morpholine
CAS:
26103-48-0
MF:
C9H12N2O3S
Structure:
Chemical Name:
2-Bromo-N-methylbenzenesulphonamide
CAS:
98192-14-4
MF:
C7H8BrNO2S
Structure:
Chemical Name:
1-Fluoro-4-(pyrrolidinosulfonyl)benzene
CAS:
157187-14-9
MF:
C10H12FNO2S
Structure:
Chemical Name:
N-Benzyl-2-bromobenzenesulfonamide
CAS:
321704-27-2
MF:
C13H12BrNO2S
Structure:
Chemical Name:
4-BROMO-N-BUTYLBENZENESULPHONAMIDE
CAS:
1984-28-7
MF:
C10H14BrNO2S
Structure:
Chemical Name:
4-BROMO-N-(2-HYDROXYETHYL)BENZENESULPHONAMIDE
CAS:
59724-43-5
MF:
C8H10BrNO3S
Structure:
Chemical Name:
5-BROMO-N-ETHYL-2-METHOXYBENZENESULPHONAMIDE
CAS:
717892-29-0
MF:
C9H12BrNO3S
Structure:
Chemical Name:
5-BROMOPYRIDINE-3-SULPHONAMIDE 98
CAS:
62009-33-0
MF:
C5H5BrN2O2S
Structure:
Chemical Name:
4-(4-BROMOBENZENESULFONYL)MORPHOLINE
CAS:
834-67-3
MF:
C10H12BrNO3S
Structure:
Chemical Name:
Sulfalen
CAS:
152-47-6
MF:
C11H12N4O3S
Structure:
Chemical Name:
Sulfameter
CAS:
651-06-9
MF:
C11H12N4O3S
Structure:
Chemical Name:
N-BENZYL 4-BROMOBENZENESULFONAMIDE
CAS:
3609-87-8
MF:
C13H12BrNO2S
Structure:
Chemical Name:
4-(N-(3-CHLOROPROPYL)SULFAMOYL)PHENYLBORONIC ACID
CAS:
874219-48-4
MF:
C9H13BClNO4S
Structure:
Chemical Name:
4-METHOXY-3-(PYRROLIDIN-1-YLSULPHONYL)BENZENEBORONIC ACID
CAS:
874219-52-0
MF:
C11H16BNO5S
Structure:
Chemical Name:
4-METHOXY-3-(N,N-DIETHYLSULFAMOYL)PHENYLBORONIC ACID
CAS:
871333-03-8
MF:
C11H18BNO5S
Structure:
Chemical Name:
2-METHYL-5-(PYRROLIDIN-1-YLSULFONYL)PHENYLBORONIC ACID
CAS:
871333-01-6
MF:
C11H16BNO4S
Structure:
Chemical Name:
5-(N-TERT-BUTYLSULFAMOYL)-2-METHYLPHENYLBORONIC ACID
CAS:
874219-47-3
MF:
C11H18BNO4S
Structure:
Chemical Name:
3-BROMO,N, N-DIMETHYLBENZENESULFONAMIDE
CAS:
153435-80-4
MF:
C8H10BrNO2S
Structure:
Chemical Name:
3-AMINO-N-ISOPROPYLBENZENESULFONAMIDE
CAS:
118837-66-4
MF:
C9H14N2O2S
Structure:
Chemical Name:
3-(Pyrrolidin-1-ylsulphonyl)pyridine
CAS:
26103-51-5
MF:
C9H12N2O2S
Structure:
Chemical Name:
1-(2-Boronophenylsulfonyl)piperidine
CAS:
957034-87-6
MF:
C11H16BNO4S
Structure:
Chemical Name:
4-BROMO-N,N-DIETHYLBENZENESULPHONAMIDE
CAS:
90944-62-0
MF:
C10H14BrNO2S
Structure:
Chemical Name:
3-(N-BENZYLSULFAMOYL)-4-METHOXYPHENYLBORONIC ACID
CAS:
874219-51-9
MF:
C13H14BNO5S
Structure:
Chemical Name:
4-(N-BENZYLSULPHONAMIDO)BENZENEBORONIC ACID
CAS:
548769-96-6
MF:
C13H14BNO4S
Structure:
Chemical Name:
4-(1-PYRROLIDINYLSULFONYL)PHENYLBORONIC ACID
CAS:
486422-57-5
MF:
C10H14BNO4S
Structure:
Chemical Name:
4-BROMO-N-CYCLOHEXYLBENZENESULPHONAMIDE
CAS:
7454-76-4
MF:
C12H16BrNO2S
Structure:
Chemical Name:
4-BROMO-2-(AMINOSULPHONYL)ANISOLE
CAS:
23095-14-9
MF:
C7H8BrNO3S
Structure:
Chemical Name:
3-AMINO-N-BUTYLBENZENESULFONAMIDE
CAS:
143173-93-7
MF:
C10H16N2O2S
Structure:
Chemical Name:
3-METHYLSULFAMOYLPHENYLBORONIC ACID
CAS:
871329-75-8
MF:
C7H10BNO4S
Structure:
Chemical Name:
2-Bromo-N-(fur-2-ylmethyl)benzenesulphonamide
CAS:
849056-66-2
MF:
C11H10BrNO3S
Structure:
Chemical Name:
3-Bromo-N-isopropyl-5-nitrobenzamide
CAS:
941294-16-2
MF:
C10H11BrN2O3
Structure:
Chemical Name:
5-(N,N-DIETHYLSULFAMOYL)-2-METHYLPHENYLBORONIC ACID
CAS:
871329-80-5
MF:
C11H18BNO4S
Structure:
Chemical Name:
1-(4-BORONOPHENYLSULFONYL)AZETIDINE
CAS:
871329-68-9
MF:
C9H12BNO4S
Structure:
Chemical Name:
3-N-BUTYLSULFAMOYLPHENYLBORONIC ACID
CAS:
871329-78-1
MF:
C10H16BNO4S
Structure:
Chemical Name:
N-Phenethyl 2-bromobenzenesulphonamide
CAS:
849141-69-1
MF:
C14H14BrNO2S
Structure:
Chemical Name:
1-(4-Bromophenylsulfonyl)piperidin-4-one
CAS:
929000-54-4
MF:
C11H12BrNO3S
Structure:
Chemical Name:
5-(N-BENZYLSULFAMOYL)-2-METHYLPHENYLBORONIC ACID
CAS:
871329-73-6
MF:
C14H16BNO4S
Structure:
Chemical Name:
4-METHOXY-3-(MORPHOLIN-4-YLSULPHONYL)BENZENEBORONIC ACID
CAS:
871333-02-7
MF:
C11H16BNO6S
Structure:
Chemical Name:
N-CYCLOPROPYL 3-NITROBENZENESULFONAMIDE
CAS:
401589-92-2
MF:
C9H10N2O4S
Structure:
Chemical Name:
3-BROMO-N,N-DIETHYLBENZENESULPHONAMIDE
CAS:
871269-11-3
MF:
C10H14BrNO2S
Structure:
Chemical Name:
1-(3-BROMO-4-METHYLPHENYLSULFONYL)MORPHOLINE
CAS:
850429-74-2
MF:
C11H14BrNO3S
Structure:
Chemical Name:
4-(N-ETHYLSULPHONAMIDO)BENZENEBORONIC ACID
CAS:
871329-65-6
MF:
C8H12BNO4S
Structure:
Chemical Name:
5-BROMO-N-BUTYL-2-METHOXYBENZENESULFONAMIDE
CAS:
871269-18-0
MF:
C11H16BrNO3S
Structure:
Chemical Name:
1-(3-NITROPHENYLSULFONYL)PIPERIDINE
CAS:
91619-31-7
MF:
C11H14N2O4S
Structure:
Chemical Name:
3-BROMO-N-(2-HYDROXYETHYL)BENZENESULPHONAMIDE 97
CAS:
911111-96-1
MF:
C8H10BrNO3S
Structure:
Chemical Name:
3-(2-(Pyrrolidin-1-yl)ethylcarbamoyl)phenylboronic acid, HCl
CAS:
957061-03-9
MF:
C13H20BClN2O3
Structure:
Chemical Name:
3-Ethylsulfamoylpyridine
CAS:
4810-40-6
MF:
C7H10N2O2S
Structure:
Chemical Name:
4-(3-NITROPHENYLSULFONYL)MORPHOLINE
CAS:
91619-33-9
MF:
C10H12N2O5S
Structure:
Chemical Name:
3-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE
CAS:
871269-08-8
MF:
C9H12BrNO2S
Structure:
Chemical Name:
3-(N-BENZYLSULFAMOYL)PHENYLBORONIC ACID
CAS:
690662-91-0
MF:
C13H14BNO4S
Structure:
Chemical Name:
5-BROMO-N-(2-HYDROXYETHYL)-2-METHOXYBENZENESULFONAMIDE
CAS:
871269-14-6
MF:
C9H12BrNO4S
Structure:
Chemical Name:
1,1,3-TRIOXO-TETRAHYDRO-2H-1,2-THIAZINE
CAS:
913836-20-1
MF:
C4H7NO3S
Structure:
Chemical Name:
3-Bromo-4-methylbenzenesulphonamide
CAS:
210824-69-4
MF:
C7H8BrNO2S
Structure:
Chemical Name:
3-AMINO-N-CYCLOHEXYLBENZENESULFONAMIDE
CAS:
61886-26-8
MF:
C12H18N2O2S
Structure:
Chemical Name:
3-(PIPERIDIN-1-YLSULFONYL)PHENYLBORONIC ACID
CAS:
690662-96-5
MF:
C11H16BNO4S
Structure:
Chemical Name:
2-Bromo-N,N-dipropylbenzenesulphonamide
CAS:
65000-11-5
MF:
C12H18BrNO2S
Structure:
Chemical Name:
Phenyl 4-bromobenzenesulphonate 98%
CAS:
5455-14-1
MF:
C12H9BrO3S
Structure:
Chemical Name:
1-(4-BROMOPHENYLSULFONYL)AZETIDINE
CAS:
530081-57-3
MF:
C9H10BrNO2S
Structure:
Chemical Name:
4-BROMO-N-[2-(TBDMSO)ETHYL]BENZENESULFONAMIDE
CAS:
850429-52-6
MF:
C14H24BrNO3SSi
Structure:
Chemical Name:
N-ISOPROPYL 3-NITROBENZENESULFONAMIDE
CAS:
28860-10-8
MF:
C9H12N2O4S
Structure:
Chemical Name:
N-(2,4-Dimethylphenyl) 2-bromobenzenesulfonamide
CAS:
941294-29-7
MF:
C14H14BrNO2S
Structure:
Chemical Name:
3-BROMO-N-BUTYLBENZENESULPHONAMIDE
CAS:
871269-09-9
MF:
C10H14BrNO2S
Structure:
Chemical Name:
4-(2-HYDROXYETHYLSULFAMOYL)PHENYLBORONIC ACID
CAS:
850568-77-3
MF:
C8H12BNO5S
Structure:
Chemical Name:
5-BROMO-N-CYCLOPROPYL-2-METHOXYBENZENESULPHONAMIDE 97
CAS:
914302-35-5
MF:
C10H12BrNO3S
Structure:
Chemical Name:
5-BROMO-N,N-DIETHYL-2-METHOXYBENZENESULFONAMIDE
CAS:
428471-30-1
MF:
C11H16BrNO3S
Structure:
Chemical Name:
N-ETHYL 3-NITROBENZENESULFONAMIDE
CAS:
28860-09-5
MF:
C8H10N2O4S
Structure:
Chemical Name:
1-(3-BROMO-4-METHYLPHENYLSULFONYL)PIPERIDINE
CAS:
850429-73-1
MF:
C12H16BrNO2S
Structure:
Chemical Name:
N,N-DIMETHYL 3-NITROBENZENESULFONAMIDE
CAS:
26199-83-7
MF:
C8H10N2O4S
Structure:
Chemical Name:
3-AMINO-N-BENZYLBENZENESULFONAMIDE
CAS:
303780-52-1
MF:
C13H14N2O2S
Structure:
Chemical Name:
3-AMINO-N-ETHYLBENZENESULFONAMIDE
CAS:
56445-08-0
MF:
C8H12N2O2S
Structure:
Chemical Name:
3-(N-ISOPROPYLSULFAMOYL)PHENYLBORONIC ACID
CAS:
871329-77-0
MF:
C9H14BNO4S
Structure:
Chemical Name:
N,N-Dimethyl 4-formyl-1H-imidazole-1-sulfonamide
CAS:
140174-48-7
MF:
C6H9N3O3S
Structure:
Chemical Name:
1-(5-BROMO-2-METHOXYBENZENESULPHONYL)PYRROLIDINE
CAS:
691381-10-9
MF:
C11H14BrNO3S
Structure:
Chemical Name:
N-BENZYL 3-BROMOBENZENESULFONAMIDE
CAS:
625470-36-2
MF:
C13H12BrNO2S
Structure:
Chemical Name:
4-Bromo-N,N,3-trimethylbenzenesulphonamide
CAS:
849532-31-6
MF:
C9H12BrNO2S