Sulfonamides and synergist
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Sulfa drugs developed rapidly in the 1930s, and there had been more than 20 species of the drugs for the clinical application. the status of sulfa drugs in chemotherapeutic agents declined after 1940s due to the occurrence of penicillin and other antibiotics. But sulfa drugs, whose antibacterial activity will be enhanced when combined with trimethoprim the antibacterial synergist, are still commonly used antibacterial drugs for the advantages of broad antibacterial spectrum, enabled to be administered orally, more rapid absorption. Clarifying the mechanism of the action of sulfa drugs established anti-metabolic theory and opened up a new way for the development of new drugs. Currently there are sulfadiazine and sulfamethoxazole that are used most widely in clinical.
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- Structure:
- Chemical Name:
- (S)-(-)-2-Methyl-2-propanesulfinamide
- CAS:
- 343338-28-3
- MF:
- C4H11NOS
- Structure:
- Chemical Name:
- 3-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID
- CAS:
- 148355-75-3
- MF:
- C7H10BNO4S
- Structure:
- Chemical Name:
- 3-Aminobenzenesulfonamide
- CAS:
- 98-18-0
- MF:
- C6H8N2O2S
- Structure:
- Chemical Name:
- 2-(Methanesulfonylamino)phenylboronic acid
- CAS:
- 756520-78-2
- MF:
- C7H10BNO4S
- Structure:
- Chemical Name:
- 3-CARBOXYPROPANESULFONAMIDE
- CAS:
- 175476-52-5
- MF:
- C4H9NO4S
- Structure:
- Chemical Name:
- Trimethoprim
- CAS:
- 738-70-5
- MF:
- C14H18N4O3
- Structure:
- Chemical Name:
- (R)-(+)-2-Methyl-2-propanesulfinamide
- CAS:
- 196929-78-9
- MF:
- C4H11NOS
- Structure:
- Chemical Name:
- 2-Bromobenzenesulphonyl chloride
- CAS:
- 2905-25-1
- MF:
- C6H4BrClO2S
- Structure:
- Chemical Name:
- 4-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID
- CAS:
- 380430-57-9
- MF:
- C7H10BNO4S
- Structure:
- Chemical Name:
- 3-BROMOBENZENESULFONAMIDE
- CAS:
- 89599-01-9
- MF:
- C6H6BrNO2S
- Structure:
- Chemical Name:
- 4-Bromobenzenesulfonamide
- CAS:
- 701-34-8
- MF:
- C6H6BrNO2S
- Structure:
- Chemical Name:
- Sulfadiazine
- CAS:
- 68-35-9
- MF:
- C10H10N4O2S
- Structure:
- Chemical Name:
- Silver sulfadiazine
- CAS:
- 22199-08-2
- MF:
- C10H9AgN4O2S
- Structure:
- Chemical Name:
- 2-(N,N-Dimethylsulphamoyl)phenylboronic acid
- CAS:
- 178432-25-2
- MF:
- C8H12BNO4S
- Structure:
- Chemical Name:
- 3-NITROBENZENESULFONAMIDE
- CAS:
- 121-52-8
- MF:
- C6H6N2O4S
- Structure:
- Chemical Name:
- Sulfanilamide
- CAS:
- 63-74-1
- MF:
- C6H8N2O2S
- Structure:
- Chemical Name:
- Sulfamethoxazole
- CAS:
- 723-46-6
- MF:
- C10H11N3O3S
- Structure:
- Chemical Name:
- 3-Cyanophenylboronic acid
- CAS:
- 150255-96-2
- MF:
- C7H6BNO2
- Structure:
- Chemical Name:
- Sulfasalazine
- CAS:
- 599-79-1
- MF:
- C18H14N4O5S
- Structure:
- Chemical Name:
- Sulfamerazine
- CAS:
- 127-79-7
- MF:
- C11H12N4O2S
- Structure:
- Chemical Name:
- Sulfacetamide sodium
- CAS:
- 127-56-0
- MF:
- C8H9N2NaO3S
- Structure:
- Chemical Name:
- Sulfamethoxypyridazine
- CAS:
- 80-35-3
- MF:
- C11H12N4O3S
- Structure:
- Chemical Name:
- 3-BROMO-N-TERT-BUTYLBENZENESULPHONAMIDE
- CAS:
- 308283-47-8
- MF:
- C10H14BrNO2S
- Chemical Name:
- Sulfamonomethoxine sodium
- MF:
- C11H11N4NaO3S
- Structure:
- Chemical Name:
- 2-(Morpholinosulfonyl)phenylboronic acid
- CAS:
- 957062-65-6
- MF:
- C10H14BNO5S
- Structure:
- Chemical Name:
- 2-METHANESULFONYLAMINOPHENYLBORONIC ACID, PINACOL ESTER
- CAS:
- 380430-60-4
- MF:
- C13H20BNO4S
- Structure:
- Chemical Name:
- Sulfamethazine sodium salt
- CAS:
- 1981-58-4
- MF:
- C12H15N4NaO2S
- Structure:
- Chemical Name:
- 4-(Aminosulfonyl)phenylboronic acid
- CAS:
- 613660-87-0
- MF:
- C6H8BNO4S
- Structure:
- Chemical Name:
- Phthalylsulfathiazole
- CAS:
- 85-73-4
- MF:
- C17H13N3O5S2
- Structure:
- Chemical Name:
- 3-AMINO-N,N-DIETHYL-BENZENESULFONAMIDE
- CAS:
- 10372-41-5
- MF:
- C10H16N2O2S
- Structure:
- Chemical Name:
- Mafenide hydrochloride
- CAS:
- 138-37-4
- MF:
- C7H11ClN2O2S
- Structure:
- Chemical Name:
- N-T-BUTYL 3-NITROBENZENESULFONAMIDE
- CAS:
- 424818-25-7
- MF:
- C10H14N2O4S
- Structure:
- Chemical Name:
- Succinylsulfathiazole
- CAS:
- 116-43-8
- MF:
- C13H13N3O5S2
- Structure:
- Chemical Name:
- (4-METHANESULFONYLAMINOMETHYL)PHENYL BORONIC ACID
- CAS:
- 850568-38-6
- MF:
- C8H12BNO4S
- Chemical Name:
- Policresulen
- CAS:
- 9011-02-3
- MF:
- (C15H16O8S2)n
- Structure:
- Chemical Name:
- 2-(PYRROLIDIN-1-YLSULPHONYL)BENZENEBORONIC ACID 97
- CAS:
- 913835-83-3
- MF:
- C10H14BNO4S
- Structure:
- Chemical Name:
- IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE
- CAS:
- 78162-58-0
- MF:
- C5H9N3O2S
- Structure:
- Chemical Name:
- P-CHLOROSULFONYLDIHYDROCINNAMIC ACID
- CAS:
- 63545-54-0
- MF:
- C9H9ClO4S
- Structure:
- Chemical Name:
- Sulfacetamide
- CAS:
- 144-80-9
- MF:
- C8H10N2O3S
- Structure:
- Chemical Name:
- SULFAMETHIZOLE
- CAS:
- 144-82-1
- MF:
- C9H10N4O2S2
- Structure:
- Chemical Name:
- 3-(PIPERIDINOSULFONYL)ANILINE
- CAS:
- 22184-99-2
- MF:
- C11H16N2O2S
- Structure:
- Chemical Name:
- 3-(1-PYRROLIDINYLSULFONYL)ANILINE
- CAS:
- 91619-38-4
- MF:
- C10H14N2O2S
- Structure:
- Chemical Name:
- Sulfadimethoxine sodium salt
- CAS:
- 1037-50-9
- MF:
- C12H15N4NaO4S
- Structure:
- Chemical Name:
- 3-AMINO-N-CYCLOPROPYLBENZENESULFONAMIDE
- CAS:
- 459434-39-0
- MF:
- C9H12N2O2S
- Structure:
- Chemical Name:
- Sodium sulfadiazine
- CAS:
- 547-32-0
- MF:
- C10H11N4NaO2S
- Structure:
- Chemical Name:
- (3-AMINOSULPHONYL)BENZENEBORONIC ACID
- CAS:
- 850568-74-0
- MF:
- C6H8BNO4S
- Structure:
- Chemical Name:
- Sulfathiazole
- CAS:
- 72-14-0
- MF:
- C9H9N3O2S2
- Structure:
- Chemical Name:
- Sulfaguanidine
- CAS:
- 57-67-0
- MF:
- C7H10N4O2S
- Structure:
- Chemical Name:
- Sulfadimethoxine
- CAS:
- 122-11-2
- MF:
- C12H14N4O4S
- Structure:
- Chemical Name:
- 3-(MORPHOLINOSULFONYL)ANILINE
- CAS:
- 22184-97-0
- MF:
- C10H14N2O3S
- Structure:
- Chemical Name:
- Sulfamethazine
- CAS:
- 57-68-1
- MF:
- C12H14N4O2S
- Structure:
- Chemical Name:
- N,N-DIMETHYL 4-IODO-1H-IMIDAZOLE-1-SULFONAMIDE
- CAS:
- 135773-25-0
- MF:
- C5H8IN3O2S
- Structure:
- Chemical Name:
- 4-BROMO-N,N-DIMETHYLBENZENESULFONAMIDE
- CAS:
- 707-60-8
- MF:
- C8H10BrNO2S
- Structure:
- Chemical Name:
- 4-(N,N-DIMETHYLSULPHONAMIDO)BENZENEBORONIC ACID
- CAS:
- 486422-59-7
- MF:
- C8H12BNO4S
- Structure:
- Chemical Name:
- 3-BROMO-N-ETHYLBENZENESULPHONAMIDE
- CAS:
- 871269-07-7
- MF:
- C8H10BrNO2S
- Structure:
- Chemical Name:
- 3-BROMO-N-METHYLBENZENESULPHONAMIDE
- CAS:
- 153435-79-1
- MF:
- C7H8BrNO2S
- Structure:
- Chemical Name:
- 4-BROMO-N-ETHYLBENZENESULPHONAMIDE
- CAS:
- 1984-25-4
- MF:
- C8H10BrNO2S
- Structure:
- Chemical Name:
- 1-(4-BROMOPHENYLSULFONYL)PYRROLIDINE
- CAS:
- 136350-52-2
- MF:
- C10H12BrNO2S
- Structure:
- Chemical Name:
- 3-(Piperidin-1-ylsulphonyl)pyridine
- CAS:
- 26103-49-1
- MF:
- C10H14N2O2S
- Structure:
- Chemical Name:
- 2-Bromo-N,N-dimethylbenzenesulphonamide
- CAS:
- 65000-13-7
- MF:
- C8H10BrNO2S
- Structure:
- Chemical Name:
- 5-Bromo-N,N-diethylpyridine-3-sulphonamide
- CAS:
- 62009-37-4
- MF:
- C9H13BrN2O2S
- Structure:
- Chemical Name:
- 2-Bromo-N-ethylbenzenesulphonamide
- CAS:
- 169189-80-4
- MF:
- C8H10BrNO2S
- Structure:
- Chemical Name:
- Sulfathiazole sodium
- CAS:
- 144-74-1
- MF:
- C9H10N3NaO2S2
- Structure:
- Chemical Name:
- N-BENZYL 5-BROMO-2-METHOXYBENZENESULFONAMIDE
- CAS:
- 446308-82-3
- MF:
- C14H14BrNO3S
- Structure:
- Chemical Name:
- 2-([(4-BROMOPHENYL)SULFONYL]AMINO)ACETIC ACID
- CAS:
- 13029-73-7
- MF:
- C8H8BrNO4S
- Structure:
- Chemical Name:
- 4-BROMO-N-METHYL-BENZENESULFONAMIDE
- CAS:
- 703-12-8
- MF:
- C7H8BrNO2S
- Structure:
- Chemical Name:
- 3-BROMO-N-PYRROLIDIN-1-YLBENZENESULPHONAMIDE
- CAS:
- 214210-14-7
- MF:
- C10H12BrNO2S
- Structure:
- Chemical Name:
- 3-(N-MORPHOLINYLSULPHONAMIDO)BENZENEBORONIC ACID
- CAS:
- 871329-60-1
- MF:
- C10H14BNO5S
- Structure:
- Chemical Name:
- (4-METHYLAMINOSULPHONYL)BENZENE BORONIC ACID
- CAS:
- 226396-31-2
- MF:
- C7H10BNO4S
- Structure:
- Chemical Name:
- SULFISOMIDINE
- CAS:
- 515-64-0
- MF:
- C12H14N4O2S
- Structure:
- Chemical Name:
- N-BENZYL 3-BROMO-4-METHYLBENZENESULFONAMIDE
- CAS:
- 850429-67-3
- MF:
- C14H14BrNO2S
- Structure:
- Chemical Name:
- 4-METHOXY-3-(PIPERIDIN-1-YLSULPHONYL)BENZENEBORONIC ACID
- CAS:
- 874219-18-8
- MF:
- C12H18BNO5S
- Structure:
- Chemical Name:
- N,N-DIMETHYL 4,5-DIIODO-1H-IMIDAZOLE-1-SULFONAMIDE
- CAS:
- 198127-92-3
- MF:
- C5H7I2N3O2S
- Structure:
- Chemical Name:
- 2-Bromo-N-(4-fluoroBenzyl)Benzenesulphonamide
- CAS:
- 321705-40-2
- MF:
- C13H11BrFNO2S
- Structure:
- Chemical Name:
- 4-(N-BUTYLSULPHONAMIDO)BENZENEBORONIC ACID
- CAS:
- 850589-32-1
- MF:
- C10H16BNO4S
- Structure:
- Chemical Name:
- 1-(4-BROMOPHENYLSULFONYL)PIPERIDINE
- CAS:
- 834-66-2
- MF:
- C11H14BrNO2S
- Structure:
- Chemical Name:
- 3-(N,N-DIMETHYLSULPHONAMIDO)BENZENEBORONIC ACID
- CAS:
- 871329-59-8
- MF:
- C8H12BNO4S
- Structure:
- Chemical Name:
- 4-Bromo-N-(4-methoxybenzyl)benzenesulfonamide
- CAS:
- 329939-43-7
- MF:
- C14H14BrNO3S
- Structure:
- Chemical Name:
- 4-(N,N-DIETHYLSULPHONAMIDO)BENZENEBORONIC ACID
- CAS:
- 850568-76-2
- MF:
- C10H16BNO4S
- Structure:
- Chemical Name:
- Sulfabenzamide
- CAS:
- 127-71-9
- MF:
- C13H12N2O3S
- Structure:
- Chemical Name:
- 4-(TERT-BUTYLAMINOSULPHONYL)BENZENEBORONIC ACID
- CAS:
- 208516-15-8
- MF:
- C10H16BNO4S
- Structure:
- Chemical Name:
- 4-(AMINOMETHYL)BENZENESULFONAMIDE
- CAS:
- 138-39-6
- MF:
- C7H10N2O2S
- Structure:
- Chemical Name:
- N-(2-AMINOETHYL) 4-BROMOBENZENESULFONAMIDE
- CAS:
- 90002-56-5
- MF:
- C8H11BrN2O2S
- Structure:
- Chemical Name:
- 1,4-BUTANESULTAM
- CAS:
- 37441-50-2
- MF:
- C4H9NO2S
- Structure:
- Chemical Name:
- Mafenide acetate
- CAS:
- 13009-99-9
- MF:
- C9H14N2O4S
- Structure:
- Chemical Name:
- 4-BROMO-N-(3-CHLOROPROPYL)BENZENESULPHONAMIDE
- CAS:
- 98768-71-9
- MF:
- C9H11BrClNO2S
- Structure:
- Chemical Name:
- 2-Bromo-N-(tert-butyl)benzenesulphonamide
- CAS:
- 138733-50-3
- MF:
- C10H14BrNO2S
- Structure:
- Chemical Name:
- 4-Bromo-N-butylbenzamide
- CAS:
- 78080-34-9
- MF:
- C11H14BrNO
- Structure:
- Chemical Name:
- N-Isopropyl 2-bromobenzenesulfonamide
- CAS:
- 951883-94-6
- MF:
- C9H12BrNO2S
- Structure:
- Chemical Name:
- 4-BROMO-N-CYCLOPROPYLBENZENESULPHONAMIDE
- CAS:
- 331950-30-2
- MF:
- C9H10BrNO2S
- Structure:
- Chemical Name:
- 2-METHYL-5-(N-MORPHOLINYLSULFONYL)PHENYLBORONIC ACID
- CAS:
- 871329-74-7
- MF:
- C11H16BNO5S
- Structure:
- Chemical Name:
- (3-METHANESULFONYLAMINOMETHYL)BENZENEBORONIC ACID
- CAS:
- 850568-39-7
- MF:
- C8H12BNO4S
- Structure:
- Chemical Name:
- 3-AMINO-N-(TERT-BUTYL)BENZENESULFONAMIDE
- CAS:
- 608523-94-0
- MF:
- C10H16N2O2S
- Structure:
- Chemical Name:
- Sulfamonomethoxine
- CAS:
- 1220-83-3
- MF:
- C11H12N4O3S
- Structure:
- Chemical Name:
- 2-(N,N-diethylsulfamoyl)phenylboronic acid
- CAS:
- 957061-16-4
- MF:
- C10H16BNO4S
- Structure:
- Chemical Name:
- 3-(PYRROLIDIN-1-YLSULFONYL)PHENYLBORONIC ACID
- CAS:
- 871329-61-2
- MF:
- C10H14BNO4S
- Structure:
- Chemical Name:
- 4-(N-ISOPROPYLSULFAMOYL)PHENYLBORONIC ACID
- CAS:
- 850589-31-0
- MF:
- C9H14BNO4S
- Structure:
- Chemical Name:
- 3-AMINO-N-METHYLBENZENESULFONAMIDE
- CAS:
- 459434-40-3
- MF:
- C7H10N2O2S
- Structure:
- Chemical Name:
- 4-(N-CYCLOPROPYLSULPHONAMIDO)BENZENEBORONIC ACID
- CAS:
- 871329-67-8
- MF:
- C9H12BNO4S
- Structure:
- Chemical Name:
- 3-(N-CYCLOPROPYLSULPHAMOYL)BENZENEBORONIC ACID 98
- CAS:
- 913835-28-6
- MF:
- C9H12BNO4S