TRIMETHYLENE DI(THIOTOSYLATE) Chemical Properties

Melting point:

64-67 °C

Boiling point:

592.3±60.0 °C(Predicted)

Density 

1.340±0.06 g/cm3(Predicted)

form 

powder to crystal

color 

White to Almost white

BRN 

2020157

CAS DataBase Reference

3866-79-3

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

2930.90.2900

MSDS

• Language:English Provider:SigmaAldrich

TRIMETHYLENE DI(THIOTOSYLATE) Usage And Synthesis

Uses

Trimethylene Di(thiotosylate) is used as a reactant in the enantioselective total synthesis of (-)-O-methylpallidinine, which is a naturally occurring morphinan alkaloid.

Reactions

1,3-Propanedithiol Bis(p-toluenesulfonate) could be used in the below reactions:
dithianylation and dithiolanylation of methylene groups adjacent to carbonyl; α,α-dithianyl cycloalkanones undergo oxidative ring scission; oxidation of ketones to 1,2-diketones can be achieved by α,α-dithianylation or dithiolanation of ketones followed by hydrolysis.

Synthesis

Treatment of potassium thiotosylate, itself made by the reaction of p-Toluenesulfonyl Chloride with Potassium Hydrogen Sulfide, with 1,3-dibromopropane or 1,2-dibromoethane in the presence of Potassium Iodide affords 1,3-propanedithiol bis(p-toluenesulfonate) and 1,2-ethanedithiol bis(p-toluenesulfonate), respectively.

TRIMETHYLENE DI(THIOTOSYLATE)(3866-79-3)Related Product Information

• Styrene
• Methyl propyl disulfide
• methyl methanethiosulfinate
• Propyl Methanethiosulfonate
• S-METHYL 4-METHYLBENZENETHIOSULFONATE
• TRIMETHYLENE DI(THIOTOSYLATE)
• 1,3-Propanediyl Bismethanethiosulfonate
• ETHYL METHANETHIOSULFONATE
• S-Methyl methanethiolsulfonate
• METHYL PHENYL DISULFIDE
• PHENYLETHYLDISULFIDE
• 1,3-Dimercaptopropane