2-BENZYL-1,3-DIOXOLANE Chemical Properties

Boiling point:

115 °C

Density 

1.085

refractive index 

n20/D 1.522(lit.)

Flash point:

108 °C

solubility 

Practically insoluble in water, soluble in alcohol and oils

form 

Liquid

color 

Clear colorless to pale yellow

Odor

Clean and mild, fresh-rosy, leafy odor

Odor Type

green

LogP

1.588 (est)

CAS DataBase Reference

101-49-5

EPA Substance Registry System

1,3-Dioxolane, 2-(phenylmethyl)- (101-49-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

RTECS 

JH6768000

HS Code 

29329990

Toxicity

LD50 orl-rat: 2200 mg/kg FCTXAV 14,827,76

2-BENZYL-1,3-DIOXOLANE Usage And Synthesis

Chemical Properties

Clear colorless to pale yellow liquid

Occurrence

Has apparently not been reported to occur in nature.

Preparation

By condensation of phenylacetaldehyde and ethylene glycol (Arctander, 1969).

Safety Profile

Moderately toxic by ingestion andskin contact. When heated to decomposition it emits acridsmoke and irritating fumes.

Metabolism

Phenylacetaldehyde ethyleneglycol acetal is presumably capable of being hydrolysed to form phenylacetaldehyde and ethylene glycol (Fassett, 1963).

Purification Methods

Dissolve 2-benzyl-1,3-dioxolane in CH2Cl2, wash well with 1M NaOH, dry over K2CO3, filter, evaporate and distil it through a short path still (Kügelrohr). It has also been purified by preparative gas chromatography. [Raber & Guida Synthesis 808 1974, Lloyd & Luberoff J Org Chem 34 3949 1969, Beilstein 19 III/IV 220.]

2-BENZYL-1,3-DIOXOLANE(101-49-5)Related Product Information

• 2-BENZYL-1,3-DIOXOLANE
• RESINIFERATOXIN
• 4-METHYL-2-(1-PHENYLETHYL)-1,3-DIOXOLANE
• 1,3-DIOXOLANE, 2-(1-PHENYLETHYL)
• FEMA 2877
• Phenylacetaldehyde
• 1-BROMO-2-(1,3-DIOXOLAN-2-YLMETHYL)BENZENE
• 4-(1,3-DIOXOLAN-2-YLMETHYL)TOLUENE
• 1-CHLORO-2-(1,3-DIOXOLAN-2-YLMETHYL)BENZENE
• 1,4-DIFLUORO-2-(1,3-DIOXOLAN-2-YLMETHYL)BENZENE
• 1-CHLORO-3-FLUORO-2-(1,3-DIOXOLAN-2-YLMETHYL)BENZENE
• 1,2-DICHLORO-4-(1,3-DIOXOLAN-2-YLMETHYL)BENZENE
• 1-BROMO-3-(1,3-DIOXOLAN-2-YLMETHYL)BENZENE
• 2-(1,3-DIOXOLAN-2-YLMETHYL)-1,4-DIMETHOXYBENZENE
• 1,3-DIFLUORO-4-(1,3-DIOXOLAN-2-YLMETHYL)BENZENE
• ROPA
• 4-(1,3-DIOXOLAN-2-YLMETHYL)-1,2-DIMETHOXYBENZENE
• 1-CHLORO-3-(1,3-DIOXOLAN-2-YLMETHYL)BENZENE