Bapotulimab
Bapotulimab Basic information
- Product Name:
- Bapotulimab
- Synonyms:
-
- Bapotulimab
- Research Grade Bapotulimab (DHB96301)
- Research Grade Bapotulimab
- Bapotulimab (anti-ILDR2)
- CAS:
- 2359413-58-2
- MW:
- 0
- Mol File:
- Mol File
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Bapotulimab Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
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Bapotulimab Usage And Synthesis
Uses
Bapotulimab (BAY-1905254) is a fully human IgG2 antibody targeting immunoglobulin-like domain containing receptor 2 (ILDR2). Bapotulimab has antitumor and immunosuppressive effects[1].
in vivo
Bapotulimab (BAY-1905254; 10 mg/kg; i.p.; on days 1 and 4) shows significantly increased antigen-specific T-cell proliferation and cytotoxicity[1].
| Animal Model: | 8- to 12-week-old CD45.1-expressing C57BL/6 wild-type mice injected with OT-I transgenic T cells[1] |
| Dosage: | 10 mg/kg |
| Administration: | i.p.; on days 1 and 4 |
| Result: | Showed significantly increased antigen-specific T-cell proliferation and cytotoxicity. |
References
[1] Julia Huetter, et al. Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2). Cancer Immunol Res. 2020 Jul;8(7):895-911. DOI:10.1158/2326-6066.CIR-19-0321
BapotulimabSupplier
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
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ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
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Guangzhou Hongyuan Chemical Co.,Ltd
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- 15817493340
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Wuhan Chemstan Biotechnology Co., Ltd.
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- 027-65317797 15926423062
- 422450190@qq.com
Biolab Reagents
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