A20FMDV2 Chemical Properties

Density 

1.47±0.1 g/cm3(Predicted)

form 

Solid

color 

White to off-white

Sequence

Asn-Ala-Val-Pro-Asn-Leu-Arg-Gly-Asp-Leu-Gln-Val-Leu-Ala-Gln-Lys-Val-Ala-Arg-Thr

A20FMDV2 Usage And Synthesis

Uses

A20FMDV2 is a selective αvβ6 integrin inhibitor (IC50: 3 nM), with an activity 1,000-fold more selective for αvβ6 than for other RGD-directed integrins (αvβ3, αvβ5, and α5β1). A20FMDV2 can be derived from the foot-and-mouth disease virus. A20FMDV2 can be radiolabeled for the PET imaging of αvβ6 integrin-positive tumors[1].

References

[1] Hausner SH, et al. Use of a peptide derived from foot-and-mouth disease virus for the noninvasive imaging of human cancer: generation and evaluation of 4-[18F]fluorobenzoyl A20FMDV2 for in vivo imaging of integrin alphavbeta6 expression with positron emission tomography. Cancer Res. 2007 Aug 15;67(16):7833-40. DOI:10.1158/0008-5472.CAN-07-1026

A20FMDV2(932699-03-1)Related Product Information

• Peptide T
• Val-cit-PAB-OH
• Peptide synthesis
• Peptide impurity
• peptide CRO
• OGP (Ostegenic Growth Peptide)
• Peptide phosphorylation marker
• Peptide fluorescent modification
• GMP peptide CMO