2-Hydroxy-5-methyl-3-nitropyridine Chemical Properties

Melting point:

179 °C (dec.) (lit.)

Boiling point:

353.3±35.0 °C(Predicted)

Density 

1.24 g/mL at 25 °C(lit.)

Flash point:

179 °C

storage temp. 

2-8°C

solubility 

soluble in Dimethylformamide

form 

powder to crystal

pka

8.78±0.10(Predicted)

color 

White to Yellow

CAS DataBase Reference

7464-14-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

2933399990

MSDS

• Language:English Provider:SigmaAldrich

2-Hydroxy-5-methyl-3-nitropyridine Usage And Synthesis

Description

2-Hydroxy-5-methyl-3-nitropyridine (HMPN) is an organosynthetic compound that can be used as a feedstock for the synthesis of other compounds or as a biological inhibitor, such as in the preparation of 2-chloro-5-methyl-3-nitropyridine and transglutaminase 2 (tg2) inhibitors. It reacts with molybdenum and chloride. It is able to react with molybdenum and chloride, and it is able to increase the reaction yield and time. It is also used to explain its reactivity with xylene.

Chemical Properties

Powder or crystalline

Uses

2-Hydroxy-5-methyl-3-nitropyridine may be used in the preparation of 2-chloro-5-methyl-3-nitropyridine via chlorination, using thionyl chloride. It may also be used is preparing proteasome inhibitors containing 5-methylpyridin-2(1H)-one moiety.

2-Hydroxy-5-methyl-3-nitropyridine(7464-14-4)Related Product Information

• 2,4,6-Collidine
• Tribenuron methyl
• METSULFURON METHYL
• 2-Hydroxy-5-nitropyridine
• 3-Nitro-2-pyridinol
• Methylparaben
• CHLOROPHOSPHONAZO III
• Methyl salicylate
• Methyl acrylate
• Methanol
• 4-Methylpyridine
• 2-Hydroxy-5-methylpyridine
• 2,6-Lutidine
• Methyl propyl carbonate
• Kresoxim-methyl
• 4-Hydroxy-3-nitropyridine
• Basic Violet 1
• 2-Methyl-3-nitropyridine