6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone
6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Basic information
- Product Name:
- 6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone
- Synonyms:
-
- LEVOSIMENDAN DAZINONES INTERMEDIATES
- 6-(4-AMINOPHENYL)-4,5-DIHYDRO-5-METHYL-3(2H)PYRIDAZINONE
- 6-(4-AMINO-PHENYL)-5-METHYL-4,5-DIHYDRO-2H-PYRIDAZIN-3-ONE
- 6-(4''-AMINOPHENYL)-4,5-DIHYDRO-5-METHYLPYRIDAZIN-3-ONE
- ICI 109,081
- 6-(p-Aminophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone
- 6-(4-AMINOPHENYL)-5-METHYLPYRIDAZIN-3(2H)ONE, 98+%
- 1,4-Dihydro-4-methyl-3-(4-aminophenyl)pyridazine-6(5H)-one
- CAS:
- 36725-28-7
- MF:
- C11H13N3O
- MW:
- 203.24
- Product Categories:
-
- (intermediate of levosimendan)
- Mol File:
- 36725-28-7.mol
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6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Chemical Properties
- Melting point:
- 194.0 to 198.0 °C
- Density
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- 13.90±0.60(Predicted)
- color
- Pale Yellow to Brown
- InChI
- InChI=1S/C11H13N3O/c1-7-6-10(15)13-14-11(7)8-2-4-9(12)5-3-8/h2-5,7H,6,12H2,1H3,(H,13,15)
- InChIKey
- NWUOGOISBQCNKQ-UHFFFAOYSA-N
- SMILES
- C1(=O)NN=C(C2=CC=C(N)C=C2)C(C)C1
- CAS DataBase Reference
- 36725-28-7(CAS DataBase Reference)
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6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Usage And Synthesis
Uses
AMDP3 (4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one) acts as a cardiac troponin effecter, resulting in activation of cardiac muscle contractions. It’s an analogue to Levosimendan (L378000), positive inotropic agent with vasodilating activity.
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6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone(36725-28-7)Related Product Information
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- (R)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone