Basic information Safety Supplier Related

6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

Basic information Safety Supplier Related

6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Basic information

Product Name:
6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone
Synonyms:
  • LEVOSIMENDAN DAZINONES INTERMEDIATES
  • 6-(4-AMINOPHENYL)-4,5-DIHYDRO-5-METHYL-3(2H)PYRIDAZINONE
  • 6-(4-AMINO-PHENYL)-5-METHYL-4,5-DIHYDRO-2H-PYRIDAZIN-3-ONE
  • 6-(4''-AMINOPHENYL)-4,5-DIHYDRO-5-METHYLPYRIDAZIN-3-ONE
  • ICI 109,081
  • 6-(p-Aminophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone
  • 6-(4-AMINOPHENYL)-5-METHYLPYRIDAZIN-3(2H)ONE, 98+%
  • 1,4-Dihydro-4-methyl-3-(4-aminophenyl)pyridazine-6(5H)-one
CAS:
36725-28-7
MF:
C11H13N3O
MW:
203.24
Product Categories:
  • (intermediate of levosimendan)
Mol File:
36725-28-7.mol
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6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Chemical Properties

Melting point:
194.0 to 198.0 °C
Density 
1.30±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
13.90±0.60(Predicted)
color 
Pale Yellow to Brown
InChI
InChI=1S/C11H13N3O/c1-7-6-10(15)13-14-11(7)8-2-4-9(12)5-3-8/h2-5,7H,6,12H2,1H3,(H,13,15)
InChIKey
NWUOGOISBQCNKQ-UHFFFAOYSA-N
SMILES
C1(=O)NN=C(C2=CC=C(N)C=C2)C(C)C1
CAS DataBase Reference
36725-28-7(CAS DataBase Reference)
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Safety Information

HS Code 
2933.99.8290
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6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Usage And Synthesis

Uses

AMDP3 (4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one) acts as a cardiac troponin effecter, resulting in activation of cardiac muscle contractions. It’s an analogue to Levosimendan (L378000), positive inotropic agent with vasodilating activity.

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