Basic information Safety Supplier Related

8-Nitro-D-guanosine

Basic information Safety Supplier Related

8-Nitro-D-guanosine Basic information

Product Name:
8-Nitro-D-guanosine
Synonyms:
  • 8-Nitro-D-guanosine
  • Guanosine, 8-nitro-
  • 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-nitro-1H-purin-6-one
  • 8-nirtoGuanosine
CAS:
337536-53-5
MF:
C10H12N6O7
MW:
328.24
Product Categories:
  • Amines
  • Bases & Related Reagents
  • Heterocycles
  • Mutagenesis Research Chemicals
  • Nucleotides
Mol File:
337536-53-5.mol
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8-Nitro-D-guanosine Chemical Properties

Boiling point:
841.0±75.0 °C(Predicted)
Density 
2.50±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol(Slightly), Water (Slightly, Heated, Sonicated)
pka
12.90±0.70(Predicted)
form 
Solid
color 
Orange to Dark Orange
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8-Nitro-D-guanosine Usage And Synthesis

Chemical Properties

Orange Solid

Uses

A highly reactive redox-active nucleic acid derivative that is formed in cellular RNA as biomarker of exposure to reactive nitrogen species. Recent studies suggest that it might contribute to the pathogenesis of inflammation-associated carcinogenesis.

Uses

A highly reactive redox-active nucleic acid derivative that is is formed in cellular RNA as biomarker of exposure to reactive nitrogen species. Recent studies suggest that it might contribute to the p athogenesis of inflammation-associated carcinogenesis.

Definition

ChEBI: Guanosine substituted at the purine 8-position by a nitro group.

8-Nitro-D-guanosineSupplier

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