CHLORODIBROMOMETHANE Chemical Properties

Melting point:

−22 °C(lit.)

Boiling point:

119-120 °C748 mm Hg(lit.)

Density 

2.451 g/mL at 25 °C(lit.)

vapor pressure 

76 at 20 °C (Schwille, 1988)

refractive index 

n20/D 1.547(lit.)

Flash point:

115-118°C

storage temp. 

2-8°C

solubility 

acetone: soluble

color 

Clear, colorless to pale yellow, heavy liquid

Water Solubility 

Not miscible or difficult to mix in water.

Sensitive 

Moisture & Light Sensitive

Merck 

14,2135

BRN 

1731046

Henry's Law Constant

In seawater (salinity 30.4‰): 2.78, 5.56, and 10.13 at 0, 10, and 20 °C, respectively (Moore et al., 1995)

CAS DataBase Reference

124-48-1(CAS DataBase Reference)

IARC

3 (Vol. 52, 71) 1999

EPA Substance Registry System

Chlorodibromomethane (124-48-1)

Safety Information

Hazard Codes 

Xn,Xi,T,F

Risk Statements 

22-39/23/24/25-23/24/25-11

Safety Statements 

45-36/37/39-26-36/37-16-7

RIDADR 

2810

WGK Germany 

3

RTECS 

PA6360000

F 

8-10-21

TSCA 

T

HazardClass 

IRRITANT

PackingGroup 

III

HS Code 

29034980

Hazardous Substances Data

124-48-1(Hazardous Substances Data)

Toxicity

LD50 in male, female rats (mg/kg): 370, 760 orally (Aida); in male, female mice (mg/kg): 800, 1200 by gavage (Bowman)

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

CHLORODIBROMOMETHANE Usage And Synthesis

Description

Dibromochloromethane is a clear colorlessliquid. Molecular weight = 208.29; Boiling point =119-120℃; Freezing/Melting point = 222℃. Alsoreported as #20℃.

Chemical Properties

clear light yellow to orange liquid

Chemical Properties

Dibromochloromethane is a clear colorless liq- uid.

Uses

A volatile halogenated methane present in trace amounts in drinking water as a result of the water treatment process. It is useful as chain transfer agents in PVC polymerization.

Uses

One of four common trihalomethanes formed after chlorination of water supplies; in the past used to make fire extinguisher fluids,spray can propellants, refrigerator fluids, and pesticides; only small amounts currently produced for laboratory use

Uses

Chemical reagent/intermediate in organic synthesis.

Definition

ChEBI: Chlorodibromomethane is an organochlorine compound.

General Description

Clear colorless to yellow-orange liquid. Density 2.451 g / cm3. No flash point.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

CHLORODIBROMOMETHANE is incompatible with strong bases, strong oxidizing agents and magnesium

Health Hazard

Chlorodibromomethane is a central nervous system (CNS) depressant at extremely high concentrations; it is toxic to the liver and kidneys of rodents and induces hepatocellular tumors in mice after long-term exposure.
In animal studies, the oral LD50 typically ranges between 800 and 1200 mg/kg.1,2 Acute signs of intoxication include sedation, flaccid muscle tone, ataxia, and prostration; death is due to CNS depression. In cases in which death does not occur until several days after acute exposure, hepatic and renal injury may be the cause of death.

Fire Hazard

CHLORODIBROMOMETHANE is probably combustible.

Safety Profile

Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic data. Human mutation data reported. Compounds of this type are generally irritating and narcotic. See also BROMOFORM and CHLOROFORM. When heated to decomposition it emits toxic fumes of Cland Br-.

Potential Exposure

Dibromochloromethane is used as a chemical intermediate in the manufacture of fire extinguishing agents; aerosol propellants; refrigerants, and pesticides. Dibromochloromethane has been detected in drinking water in the United States. It is believed to be formed by the haloform reaction that may occur during

First aid

Skin Contact: Flood all areas of body thathave contacted the substance with water. Do not wait toremove contaminated clothing; do it under the water stream.Use soap to help assure removal. Isolate contaminatedclothing when removed to prevent contact by others.Eye Contact: Remove any contact lenses at once. Flusheyes well with copious quantities of water or normal salinefor at least 2030 min. Seek medical attention.Inhalation: Leave contaminated area immediately; breathefresh air. Proper respiratory protection must be supplied toany rescuers. If coughing, difficult breathing or any othersymptoms develop, seek medical attention at once, even ifsymptoms develop many hours after exposure.Ingestion: If convulsions are not present, give a glass ortwo of water or milk to dilute the substance. Assure that theperson’s airway is unobstructed and contact a hospital orpoison center immediately for advice on whether or not toinduce vomiting

Environmental Fate

Biological. Dibromochloromethane showed significant degradation with gradual adaptation in a static-culture flask-screening test (settled domestic wastewater inoculum) conducted at 25 °C. At concentrations of 5 and 10 mg/L, percent losses after 4 wk of incubation were 39 and 25, respectively. At a substrate concentration of 5 mg/L, 16% was lost due to volatilization after 10 d (Tabak et al., 1981).
Surface Water. The estimated volatilization half-life of dibromochloromethane from rivers and streams is 45.9 h (Kaczmar et al., 1984).
Photolytic. Water containing 2,000 ng/μL of dibromochloromethane and colloidal platinum catalyst was irradiated with UV light. After 20 h, dibromochloromethane degraded to 80 ng/μL bromochloromethane, 22 ng/μL methyl chloride, and 1,050 ng/μL methane. A duplicate experiment was performed but 1 g zinc was added. After about 1 h, total degradation was achieved. Presumed transformation products include methane, bromide, and chloride ions (Wang and Tan, 1988).
Chemical/Physical. The estimated hydrolysis half-life in water at 25 °C and pH 7 is 274 yr (Mabey and Mill, 1978). Hydrogen gas was bubbled in an aqueous solution containing 18.8 μmol dibromochloromethane. After 24 h, only 18% of the dibromochloromethane reacted to form methane and minor traces of ethane. In the presence of colloidal platinum catalyst, the reaction proceeded at a much faster rate forming the same end products (Wang et al., 1988).

storage

Color Code—Green: General storage may be used.Prior to working with this chemical you should be trainedon its proper handling and storage. Store in tightly closedcontainers under an inert atmosphere, away from light, in arefrigerator. Where possible, automatically pump liquidfrom drums or other storage containers to process containers. A regulated, marked area should be established wherethis chemical is handled, used, or stored in compliance withOSHA Standard 1910.1045.

Shipping

UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explo- sions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, and magnesium.

Waste Disposal

May be destroyed by high- temperature incinerator equipped with an HCl scrubber.

CHLORODIBROMOMETHANE(124-48-1)Related Product Information

• Triethyl phosphate
• Dichloroethane
• Acetaldehyde
• 4'-tert-Butylacetophenone
• ETHYLENE
• Phosphorus pentoxide
• CHLORODIBROMOMETHANE
• 1-CHLORO-1,1-DIBROMO-2,2,2-TRIFLUOROETHANE
• Dibromomethane
• Bromochloromethane
• Methyl bromide
• DIBROMODICHLOROMETHANE
• CHLORODIBROMOACETIC ACID
• CHLORODIBROMOFLUOROMETHANE
• METHYL CHLORODIBROMOACETATE
• TRIBROMOCHLOROMETHANE
• CHLORODIBROMOACETIC ACID-1-13C
• TRIHALOMETHANE