Basic information Safety Supplier Related

YM17E

Basic information Safety Supplier Related

YM17E Basic information

Product Name:
YM17E
Synonyms:
  • YM17E
  • Urea, N,N''-[1,3-phenylenebis(methylene)]bis[N-cycloheptyl-N'-[4-(dimethylamino)phenyl]- (9CI)
  • Diglyceride acyltransferase,Inhibitor,acyl-CoA:cholesterol acyltransferase,inhibit,YM17E,Acyltransferase,Diacylglycerol acyltransferase,mono- acylglycerol acyltransferase,YM-17E
  • 1,1'-(1,3-Phenylenebis(methylene))bis(1-cycloheptyl-3-(4-(dimethylamino)phenyl)urea)
  • 1,1'-(1,3-Phenylenebis(methylene))bis(1-cycloheptyl-3-(4-(dimethylamino)phenyl)urea)
CAS:
124900-72-7
MF:
C40H56N6O2
MW:
652.93
Mol File:
124900-72-7.mol
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YM17E Chemical Properties

Boiling point:
862.7±65.0 °C(Predicted)
Density 
1.16±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
14.03±0.70(Predicted)
color 
White to off-white
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YM17E Usage And Synthesis

Biological Activity

YM17E is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) with IC50 of 44 nM in vitro in rabbit liver microsomes.

in vitro

YM17E is as potent in inhibiting ACAT activity in the liver as in the intestine, with IC 50 values of 45 and 34 nM, respectively.

target

IC50: 44 nM (ACAT in rabbit liver microsomes)

YM17ESupplier

Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Email
klq@cw-bio.com
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Email
sales@regentsciences.com
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Email
sales@chemegen.com