ETHYL 2-AMINO-5-ETHYLTHIOPHENE-3-CARBOXYLATE Chemical Properties

Melting point:

73°C

Boiling point:

312.7±42.0 °C(Predicted)

Density 

1.183±0.06 g/cm3(Predicted)

pka

0.39±0.10(Predicted)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HazardClass 

IRRITANT

HS Code 

29349990

ETHYL 2-AMINO-5-ETHYLTHIOPHENE-3-CARBOXYLATE Usage And Synthesis

Chemical Properties

Light yellow solid

Uses

Ethyl 2-Amino-5-ethylthiophene-3-carboxylate is used as a reagent in the synthesis of 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as antitumor agents. Also used as a reagent in the synthesis of the necroptosis inhibitor, Necrostatin-5 (Nec-5).

ETHYL 2-AMINO-5-ETHYLTHIOPHENE-3-CARBOXYLATE(4507-13-5)Related Product Information

• ETHYL 2-AMINO-5-ETHYLTHIOPHENE-3-CARBOXYLATE
• Ethyl thiophene-3-carboxylate
• 2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER
• 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
• ETHYL 2-ACETAMIDO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE
• ETHYL 2-[(2-CHLOROACETYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXYLATE
• ethyl 5-acetyl-2-amino-4-methyl-thiophene-3-carboxylate
• 5-ETHYL-3-THIOPHENECARBOXYLIC ACID
• ETHYL 2-((THIOXO((4-(TRIFLUOROMETHOXY)PHENYL)AMINO)METHYL)AMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE
• AURORA 3766
• AKOS AUF1322
• BUTTPARK 128\48-16
• ETHYL 2-(((1,3-DIOXOINDAN-2-YLIDENE)METHYL)AMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE
• AKOS 93369
• ETHYL 2-(((4-(TRIFLUOROMETHOXY)PHENYL)AMINO)CARBONYLAMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE
• ETHYL 2-[2-(2,4-DICHLOROPHENOXY)ACETAMIDO]-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE
• BUTTPARK 123\48-20
• ETHYL 2-(((4-CHLOROPHENYL)AMINO)CARBONYLAMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE