2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]BENZOIC ACID Chemical Properties

Melting point:

198-199 °C

Boiling point:

507.0±60.0 °C(Predicted)

Density 

1.319±0.06 g/cm3(Predicted)

vapor pressure 

0Pa at 10.6℃

form 

Crystalline

pka

3.79±0.10(Predicted)

LogP

-2.37 at 20℃

Surface tension

71.8mN/m at 1g/L and 16.5℃

2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]BENZOIC ACID Usage And Synthesis

Uses

2-Ethoxy-5-(4-methyl-1-piperazinylsulfonyl)benzoic Acid is used as a reactant in the synthesis of Sildenafil Citrate (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.

Definition

ChEBI: 2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylbenzoic acid is a 4-ethoxy-3-carboxybenzenesulfonamide in which the sulfonamide nitrogen is a member of a piperazine ring. It is a sulfonamide and a member of piperazines. It is functionally related to a benzoic acid.

2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]BENZOIC ACID(194602-23-8)Related Product Information

• Cichoric acid
• N,N-Dimethylallylamine
• 2-Ethoxybenzoyl chloride
• N-Des[2-(1-methyl-2-pyrrolidinyl)ethyl] Udenafil
• 1H-Pyrazolo[4,3-d]pyriMidine, 3-(2-Methylpropyl)-
• 5-DIMETHOXYMETHYL-BENZO[1,3]DIOXOLE
• 5-(2-ETHOXYPHENYL)-1-METHYL-3-N-PROPYL-1,6-DIHYDRO-7H-PYRAZOLO[4,3-D]-7-PYRIMIDINONE
• 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide
• Propoxyphenyl ThiohoMosidenafil
• 1-METHYL-4-NITRO-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
• 5-chloro-2-ethoxybenzoyl chloride
• 4-(2-Ethoxy benzamido)-1-methyl-3-n-propyl pyrazole-5-carboxamide.
• Sildenafil Chlorosulfonyl
• Sulfosalicylic acid
• Sildenafil Impurity F
• 5-chloro-2-ethoxybenzoic acid
• KF31327
• Desethyl Carbodenafil